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Exam (elaborations)

MSN 622 Week 5 – Rheumatoid exam with verified answers

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MSN 622 Week 5 – Rheumatoid exam with verified answers

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MSN 622 Week 5 – Rheumatoid exam
with verified answers

A 72-year-old man presents to the clinic for pre-operative evaluation. The patient says he is feeling
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well, remembers many years ago, was diagnosed with some joint condition, and was advised to
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take medications for which he would have to do blood tests regularly. He was not interested in
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doing regular blood tests and seeing a clinician regularly; hence he never took treatment for the
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disease. On examination, he has bilateral ulnar deviation and subluxation of the |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




metacarpophalangeal (MCP) joints. Hand X-ray shows erosions of MCP and proximal |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




interphalangeal (PIP) joints. Rheumatoid factor (RF) and anti-CCP antibodies are positive. Which of |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




the following is the next best step in managing this patient? - correct answer ✔Cervical spine
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radiographs



A 47-year-old woman presents to the clinic with swelling in both knees, morning stiffness lasting
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more than an hour, and pain with walking. Further history reveals bilateral hand and wrist pain.
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These symptoms have been present for about three months and have gradually progressed. The
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patient has tried over-the-counter acetaminophen without relief from the symptoms. For the past
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couple of months, she has felt tired and had a low-grade fever. She denies rashes, oral ulcers, chest
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pain, and difficulty breathing. On examinations, she has synovitis of both knees,
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metacarpophalangeal (MCP), and proximal interphalangeal (PIP) joints bilaterally. X-rays of the |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




hands do not show joint damage. Lab results for rheumatoid factor (RF), anti-CCP, and ANA are
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negative. What is the most likely diagnosis? - correct answer ✔Rheumatoid arthritis |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




A 54-year-old man with a history of rheumatoid arthritis presents to the clinic for a regular follow-
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up appointment. He has remained stable on methotrexate 15 mg every week, folic acid 1 mg daily,
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and etanercept 50 mg every week. His examination is unremarkable, with no joint tenderness or
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swelling. Routine labs are within normal limits. The patient does mention some pain along his |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




spine. Involvement of which of the following spinal segments is associated with the worst
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morbidity in this patient? - correct answer ✔Cervical spine |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




A 54-year-old female presented for evaluation at the outpatient clinic. She was diagnosed with
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rheumatoid arthritis two years ago. She has been closely followed up and found to have low-level |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




disease activity. Currently, she is managed with NSAIDs and has never received disease-modifying
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antirheumatic drugs (DMARDs). In patients with established disease, the American College of |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||

, Rheumatology recommends what type of treatment? - correct answer ✔Start monotherapy with a |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




DMARD



A 65-year-old female patient complains of joint stiffness and swelling in both hands. The stiffness
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worsens upon waking up in the morning and gradually improves after two to three hours. She
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further reports having had more trouble opening her pill bottles in the past few weeks. Which one
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of the following is going to be the most specific for reaching a diagnosis in this patient? - correct
|||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




answer ✔Anti-citrullinated protein antibodies (ACPA) |||||| |||||| |||||| ||||||




32-year-old woman presents to the healthcare provider with six months of fatigue. She also reports |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




joint pains, chest pain, and a 3 kg weight loss ever since the fatigue started. She denies recent
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travel, fever, or new sexual partners. She has no past medical history and takes no medications.
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She is sexually active with her husband of five years. Her mother has rheumatoid arthritis. Vitals
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include a blood pressure of 123/80 mmHg, a heart rate of 81/min, a respiratory rate of 18/min, and
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oxygen saturation of 99% on room air. On examination, she has a rash over her nose and an ulcer
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on her hard palate. The chest examination reveals decreased air entry in her right lung base. Her
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abdomen is soft, and there is no hepatosplenomegaly. Neurological examination is within normal |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




limits. Which of the following antibody titers most likely correlates with the disease activity in this
|||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




patient? - correct answer ✔Anti-double-stranded DNA antibodies |||||| |||||| |||||| |||||| |||||| ||||||




A 24-year-old woman presents with diffuse aching and stiffness, worsened by cold weather and
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stress. Her history is significant for Lyme disease 2 years ago treated with doxycycline 100 mg twice
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a day for 4 weeks. Her joints show no tenderness or synovitis, but she is tender over points
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bilaterally at the occiput, trapezius, lateral epicondyle, gluteals, and knee. What is the most |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




probable diagnosis? - correct answer ✔Fibromyalgia |||||| |||||| |||||| |||||| ||||||




30-year-old woman presents with widespread musculoskeletal pain, which is bilateral and involves |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




both upper and lower parts of the body for the past 4 months. She has normal laboratory findings,
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and imaging studies are unremarkable. Which of the following is a first-line medication used to
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treat this condition? - correct answer ✔Duloxetine
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40-year-old patient presented with fatigue and difficulty concentrating at work for almost a year. |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




She also complains of pain all over her body but mainly in the shoulder and neck. She has had
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multiple ED visits but all the labs came back within normal limits. What is the best initial therapy
|||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| |||||| ||||||




for this patient? - correct answer ✔Aerobic exercise
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A 40-year-old female patient presents with fatigue and insomnia for six months. She also complains
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of feeling pain all over. Her inflammatory markers came back within normal limits. There are many
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