GMS 6474 University Of Florida -GMS 6474 lecture 2
- lecture 38 Questions |2025 | Guaranteed Pass !!
Lecture 2-ANSWER
Muscles can either be ____ or ____?-ANSWER1. Voluntary
2. Involuntary
What is one question to ask when comparing voluntary to involuntary muscles?-
ANSWERHow is the underlying tissue metabolized?
Cardiac functional syncytial vs smooth muscle functional syncytial?-
ANSWERCardiac - pacemaker cells cause contractions
Smooth - vasodilation/vasoconstriction
True/False: Smooth muscle has striations?-ANSWERFALSE!
what two factors determine the force production at the sarcomere level?-
ANSWERIf they are arranged in parallel or series!
True/False: skeletal muscle cells contain many nuclei and very long-
ANSWERTRUE!
Myofibrils are responsible for what 3 things?-ANSWER1. tension generation
2. force production
,3. shortening of muscle
What is a sarcomere?-ANSWERBasic unit of muscle that extends from Z-disc to
Z-disc
Sliding filament theory?-ANSWERThe thick/thin filaments do not change but the
overlap does!
H zone?-ANSWERH for "heal" aka "light" only tails of myosin molecules
*** THIS COULD DISAPPEAR DUE BC OF CONTRACTIONS**
A-band?-ANSWERboth thick and thin
I band?-ANSWERonly thin - extends both sides of the z-disc
***THIS WILL SHORTEN IF THE MUSCLE CONTRACTS***
What is a triad?-ANSWERSR, T Tubule, SR
Why is T-Tubule important?-ANSWERmuscle cells are really long so there needs
to be something that connects the outside with the inside
**allows for better communication system**
** action potentials would not reach the myofibrils if it werent for the T-tubules***
True/False: SR keeps Ca levels low?-ANSWERTRUE!
,Lecture 3-ANSWER
What are the 3 parts of the thick filament?-ANSWER1. tail
2. hinge aka neck
3. head
Which part is responsible for the ATP activity? Aka the binding and splitting of
ATP?-ANSWERHead
Specifically?-ANSWERMyosin heavy chains
The myosin light chains are responsible for what?-ANSWERModulating the ATP
activity in cardiac/skeletal muscle
When inidividual myosin molecules are placed in a ionic and salt solution, what
happens?-ANSWERThe myosin heads will join together and tails will dimerize to
form one thick cross bridge filament
another reminder....what part of the myosin is responsible for the ATP activity?-
ANSWERThe myosin heavy chains on the myosin heads
what protein is responsible for in participating in the bipolar arrangement and
packing into sarcomere?-ANSWERMyomicin C protein
Which protein holds the myosin heads together, instead of leaving them in space?-
ANSWERtitin
, (attaches myosin to z disc)
thin filament is what?-ANSWERactin
heavy chains of myosin are going to act upon what?-ANSWERTHE ACTIN!
G actin vs F actin?-ANSWERGlomerular vs filamentous
What protein strand hides the active site on the actin?-ANSWERTropomyosin
Which part of troponin is acted upon Ca?-ANSWERC
which two proteins anchor the thin filament to the Z-disc?-ANSWER1. alpha-
actinin
2. capZ
Z disc is made up of which two proteins-ANSWERalpha actinin and CapZ
Which component attaches the sarcolemma to the outside filaments/collagen?-
ANSWERDystrophin Associated Complex
_________ links the DAC with the extracellular matrix?-ANSWERLaminin-2
(attaches to alpha/beta dystroglycans)
- lecture 38 Questions |2025 | Guaranteed Pass !!
Lecture 2-ANSWER
Muscles can either be ____ or ____?-ANSWER1. Voluntary
2. Involuntary
What is one question to ask when comparing voluntary to involuntary muscles?-
ANSWERHow is the underlying tissue metabolized?
Cardiac functional syncytial vs smooth muscle functional syncytial?-
ANSWERCardiac - pacemaker cells cause contractions
Smooth - vasodilation/vasoconstriction
True/False: Smooth muscle has striations?-ANSWERFALSE!
what two factors determine the force production at the sarcomere level?-
ANSWERIf they are arranged in parallel or series!
True/False: skeletal muscle cells contain many nuclei and very long-
ANSWERTRUE!
Myofibrils are responsible for what 3 things?-ANSWER1. tension generation
2. force production
,3. shortening of muscle
What is a sarcomere?-ANSWERBasic unit of muscle that extends from Z-disc to
Z-disc
Sliding filament theory?-ANSWERThe thick/thin filaments do not change but the
overlap does!
H zone?-ANSWERH for "heal" aka "light" only tails of myosin molecules
*** THIS COULD DISAPPEAR DUE BC OF CONTRACTIONS**
A-band?-ANSWERboth thick and thin
I band?-ANSWERonly thin - extends both sides of the z-disc
***THIS WILL SHORTEN IF THE MUSCLE CONTRACTS***
What is a triad?-ANSWERSR, T Tubule, SR
Why is T-Tubule important?-ANSWERmuscle cells are really long so there needs
to be something that connects the outside with the inside
**allows for better communication system**
** action potentials would not reach the myofibrils if it werent for the T-tubules***
True/False: SR keeps Ca levels low?-ANSWERTRUE!
,Lecture 3-ANSWER
What are the 3 parts of the thick filament?-ANSWER1. tail
2. hinge aka neck
3. head
Which part is responsible for the ATP activity? Aka the binding and splitting of
ATP?-ANSWERHead
Specifically?-ANSWERMyosin heavy chains
The myosin light chains are responsible for what?-ANSWERModulating the ATP
activity in cardiac/skeletal muscle
When inidividual myosin molecules are placed in a ionic and salt solution, what
happens?-ANSWERThe myosin heads will join together and tails will dimerize to
form one thick cross bridge filament
another reminder....what part of the myosin is responsible for the ATP activity?-
ANSWERThe myosin heavy chains on the myosin heads
what protein is responsible for in participating in the bipolar arrangement and
packing into sarcomere?-ANSWERMyomicin C protein
Which protein holds the myosin heads together, instead of leaving them in space?-
ANSWERtitin
, (attaches myosin to z disc)
thin filament is what?-ANSWERactin
heavy chains of myosin are going to act upon what?-ANSWERTHE ACTIN!
G actin vs F actin?-ANSWERGlomerular vs filamentous
What protein strand hides the active site on the actin?-ANSWERTropomyosin
Which part of troponin is acted upon Ca?-ANSWERC
which two proteins anchor the thin filament to the Z-disc?-ANSWER1. alpha-
actinin
2. capZ
Z disc is made up of which two proteins-ANSWERalpha actinin and CapZ
Which component attaches the sarcolemma to the outside filaments/collagen?-
ANSWERDystrophin Associated Complex
_________ links the DAC with the extracellular matrix?-ANSWERLaminin-2
(attaches to alpha/beta dystroglycans)
