Indication MOA Adverse Effects Nursing Concerns
Cyclosporine Used to prevent transplant Decreases immune response by Decreased immune response, Physical assessment focused on
(Sandimmune) rejection or quiet an decreasing WBC (T Lymphocyte) very high infection risk, renal function: BUN, Creatinine,
overactive immune system Leukopenia, sore throat, joint urinary function and weight; Liver
(e.g. RA) pain, fever, chills function: labs should be
Immunosuppressant performed/documented before,
Teach pt. to report fever, chills, during and after treatment; hand
sore throat, tremors, bleeding washing with antibacterial soap;
gums and increased BP; avoid invasive procedures; protect
discontinue if urinating dark skin; avoid tampons and rectal
urine, jaundice or light-colored temperature route and
stools occur suppositories; oral care and hygiene;
avoid crowds; wear shoes; dressing
and bandages need to be changed
daily and when soiled; keep supplies
away from other patients; avoid
fresh fruits, veggies and uncooked
foods; prophylactic antibiotics
before surgery
Phenylephrine Nasal congestion, Activate Alpha 1 Adrenergic Headache, Restlessness, ALPHA AGONISTS SPECIFIC
(Neosynephrine) hypotension, or to produce Receptors Insomnia, Euphoria, Other examples: Pseudoephedrine
mydriasis during eye exams Palpitations/Tachycardia, (Sudafed) for nasal use and
(Sudafed & Visine) Dysrhythmias, Hypertension, Tetrahydrozoline (Visine) for ocular
Alpha 1 Adrenergic Pulmonary edema, Cardiac use; Monitor cardiac and respiratory
Agonist arrest status; Baseline Vitals; I&O;
Underlying problem/preexisting
conditions; Examine IV sites
frequently; Remove contact
lenses/dark eye protection after eye
use; Limit use to 3-5 days intranasal
Carbamazepine (Tegretol) Drug of choice for tonic Inhibits sodium channels blocking Many adverse effects (skin Used with phenytoin in patients
clonic and partial seizures repetitive sustained firing of problems, aplastic anemia, requiring polytherapy; complete
Anticonvulsant neurons; other mechanisms likely hypersensitivity) Do not eat or neurological assessment including
but not completely understood drink grapefruit juice when pupil response, LOC, orientation,
, taking this cognition, motor and verbal
THINK SODIUM response; baseline history; previous
med reactions; vitals; CBC;
, electrolytes; monitor seizure activity
and ensure environmental safety;
assess drug serum levels; MONITOR
FOR BLOOD DYSCRASIAS!
Sympathomimetic Adrenergics, or General Adverse Effects Assess for underlying problems and
Decongestants sympathomimetics, are Headache preexisting conditions
(Adrenergics) used in the treatment of a Restlessness Establish a baseline of vital signs
wide variety of illnesses and Insomnia Monitor respiratory status
conditions. Euphoria Use cardiac/resuscitation monitor
Palpitations including BP
Dysrhythmias Inform prescriber changes of I/O
Hypertension ALPHA AGONISTS SPECIFIC
Pulmonary edema Examine IV sites frequently
Remove contact lenses and dark eye
protection after ophthalmic use
Use in limited 3-5 days for intranasal
decongestion
Mebendazole (Vermox) Ascariasis (roundworm); Rapidly kills and eliminates Important to identify causative
Enterobiasis (pinworm); parasite worm; ensure compliance to
Antiparasitic Hookworm; Tapeworm; treatment regimen; Labs including
Rapidly kills and eliminates CBC and hemoglobin
parasites
Metronidazole (Flagyl) Caused by intestinal Kills organisms by binding to DNA May cause metallic taste and Educate patient the drug may cause
parasites acquired through and RNA affecting DNA repair and dark urine metallic taste and dark urine
Antibiotic contaminated water and RNA synthesis
food; it can also be used
for C. Diff; Good for
protozoas: amebiasis,
giardiasis, and
cryptosporidiosis
Steroid inhalers Fluticasone (Flovent); Inhaled Corticosteroids MOA Fluticasone (Flovent): most
Budesonide (Pulmicort); Reduces inflammation and prescribed, cost effective inhaled
Beclomethasone (Qvar) immune response thus reducing corticosteroid
frequency of asthma attacks Budesonide (Pulmicort): expensive
corticosteroid with nebulizer
Epoetin alpha (Epogen) chemotherapy induced stimulate RBC production and
anemia decrease duration of
, Colony Stimulating Factor chemotherapy induced anemia
Atenolol (Tenormin) Used for hypertension, Block beta 1 receptor; selective Fewer side effects than Fewer side effects than nonselective
angina, heart failure nonselective; OK to use in OK to use in COPD and asthma