Pharmacology zIllustrated z Reviews z8th zEdition zWhalen zTest zBank
TABLE zOF zCONTENT
z
Chapter z 1: z Pharmacokinetics
Chapter z2: zDrug–Receptor zInteractions zand zPharmacodynamics
z Chapter z3: z The z Autonomic zNervous zSystem
Chapter z4: zCholinergic zAgonists
zChapter z5: zCholinergic
zAntagonists zChapter z6:
zAdrenergic zAgonists zChapter z7:
zAdrenergic zAntagonists
Chapter z8: zDrugs zfor zNeurodegenerative zDiseases
zChapter z9: zAnxiolytic zand zHypnotic zDrugs
Chapter z10: zAntidepressants
zChapter z11: zAntipsychotic zDrugs
zChapter z12: zDrugs zfor zEpilepsy
zChapter z13: zAnesthetics
Chapter z 14: z Opioids
Chapter z15: zDrugs zof zAbuse
zChapter z16: zCNS zStimulants
zChapter z17: zAntihypertensives
zChapter z18: zDiuretics
Chapter z 19: z Heart z Failure
Chapter z20: zAntiarrhythmics
zChapter z21: zAntianginal zDrugs
Chapter z22: zAnticoagulants zand zAntiplatelet zAgents
z Chapter z23: zDrugs zfor zHyperlipidemia
Chapter z24: zPituitary zand zThyroid
zChapter z25: zDrugs zfor zDiabetes
Chapter z26: zEstrogens zand zAndrogens
zChapter z27: zAdrenal zHormones
Chapter z 28: z Drugs z for z Obesity
Chapter z29: zDrugs zfor zDisorders zof zthe zRespiratory zSystem
z Chapter z30: zAntihistamines
Chapter z31: zGastrointestinal zand zAntiemetic zDrugs
zChapter z32: zDrugs zfor zUrologic z Disorders
Chapter z 33: z Drugs z for z Anemia
Chapter z34: zDrugs zfor zDermatologic zDisorders
zChapter z35: zDrugs zfor zBone zDisorders
Chapter z36: zAnti-inflammatory, zAntipyretic, zand z Analgesic zAgents
z Chapter z37: z Principles zof z Antimicrobial z Therapy
Chapter z 38: z Cell z Wall z Inhibitors
Chapter z 39: z Protein z Synthesis z Inhibitors
Chapter z40: zQuinolones, zFolic zAcid z Antagonists, z and z Urinary z Tract zAntiseptics
zChapter z41: zAntimycobacterial zDrugs
Chapter z42: zAntifungal zDrugs
zChapter z43: zAntiprotozoal zDrugs
zChapter z44: zAnthelmintic zDrugs
zChapter z45: zAntiviral zDrugs
Chapter z 46: z Anticancer z Drugs
Chapter z47: zImmunosuppressants
zChapter z48: zClinical zToxicology
,
,
, 3. The znurse zis zteaching za zpatient zwho zwill zbe zdischarged zhome zwithza zprescription zfor zan
enteric- zcoated ztablet. zWhich zstatement zby zthe zpatient z indicates zunderstanding zof zthe
z
teaching?
z
a. Izmay zcrush zthe ztablet zand zput zit zin zapplesauce zto zimprove zabsorption.
b. I zshould z consume zacidic zfoodszto zenhance zabsorption zof zthis zmedication.
c. I z should z expect z a zdelay zin zonset z of zthe zdrugs zeffects zafter ztaking zthe ztablet.
d. I zshould ztake zthis zmedication zwithzhigh-fat zfoodszto zimprove zits
action. zANS: zC
z
Enteric-coated ztablets zresist zdisintegration zin zthe zacidic zenvironment zof zthe zstomach zand
disintegrate zwhen zthey zreach zthe zsmall zintestine. zThere zis zusually zsome zdelay zin zonset zof
z
actions zafter ztaking zthese zmedications. zEnteric-coated ztablets zshould znot zbe zcrushed zor
z
chewed, zwhich zwould zalter zthe ztime zand zlocation zof zabsorption. zAcidic zfoods zwill znot
z
enhance zthe zabsorption zof zthe zmedication. zThe zpatient zshould znot zto zeat zhigh-fat zfood
z
before zingesting zan zenteric-coated ztablet, zbecause zhigh-fat zfoods zdecrease zthe zabsorption
z
rate.
z
DIF:zCOGNITIVE zLEVEL: zApplying z(Application) zREF: zdm z3
TOP: zNURSING zPROCESS: zNursing zIntervention
z
MSC:zNCLEX: zPhysiological zIntegrity: zPharmacological zand zParenteralzTherapies
4. A zpatient zwho zis znewly zdiagnosed zwith ztype z1 zdiabetes zmellitus zasks zwhy zinsulin
must zbe zgiven zby zsubcutaneous zinjection zinstead zof zbyzmouth. zThe znurse zwillzexplain zthat
z
this zis zbecause
z
a. absorption zis z diminished z byzthe zfirst-pass zeffects zin zthe zliver.
b. absorption zis zfaster zwhen zinsulin zis zgiven zsubcutaneously.
c. digestive zenzymes zin zthe zgastrointestinalztract zprevent zabsorption.
d. the zoral zformzis zless zpredictablezwith zmore zadverse
effects. zANS: zC
z
Insulin, zgrowth zhormones, zand zother zprotein-based zdrugs zare zdestroyed zin zthe zsmall
intestine zby zdigestive zenzymes zand zmust zbe zgiven zparenterally. zBecause zinsulin zis
z
destroyed zby zdigestive zenzymes, zit zwould znot zmake zit zto zthe zliver zfor zmetabolism zwithza
z
first-pass zeffect.zSubcutaneous ztissue zhas zfewer zblood zvessels, zso zabsorption zis zslower zin
z
such ztissue. zInsulin zis zgiven zsubcutaneously zbecause zit zis zdesirable zto zhave zit zabsorb
z
slowly.
z
DIF:zCOGNITIVE zLEVEL:zUnderstanding z(Comprehension) zREF: zdm z3
TABLE zOF zCONTENT
z
Chapter z 1: z Pharmacokinetics
Chapter z2: zDrug–Receptor zInteractions zand zPharmacodynamics
z Chapter z3: z The z Autonomic zNervous zSystem
Chapter z4: zCholinergic zAgonists
zChapter z5: zCholinergic
zAntagonists zChapter z6:
zAdrenergic zAgonists zChapter z7:
zAdrenergic zAntagonists
Chapter z8: zDrugs zfor zNeurodegenerative zDiseases
zChapter z9: zAnxiolytic zand zHypnotic zDrugs
Chapter z10: zAntidepressants
zChapter z11: zAntipsychotic zDrugs
zChapter z12: zDrugs zfor zEpilepsy
zChapter z13: zAnesthetics
Chapter z 14: z Opioids
Chapter z15: zDrugs zof zAbuse
zChapter z16: zCNS zStimulants
zChapter z17: zAntihypertensives
zChapter z18: zDiuretics
Chapter z 19: z Heart z Failure
Chapter z20: zAntiarrhythmics
zChapter z21: zAntianginal zDrugs
Chapter z22: zAnticoagulants zand zAntiplatelet zAgents
z Chapter z23: zDrugs zfor zHyperlipidemia
Chapter z24: zPituitary zand zThyroid
zChapter z25: zDrugs zfor zDiabetes
Chapter z26: zEstrogens zand zAndrogens
zChapter z27: zAdrenal zHormones
Chapter z 28: z Drugs z for z Obesity
Chapter z29: zDrugs zfor zDisorders zof zthe zRespiratory zSystem
z Chapter z30: zAntihistamines
Chapter z31: zGastrointestinal zand zAntiemetic zDrugs
zChapter z32: zDrugs zfor zUrologic z Disorders
Chapter z 33: z Drugs z for z Anemia
Chapter z34: zDrugs zfor zDermatologic zDisorders
zChapter z35: zDrugs zfor zBone zDisorders
Chapter z36: zAnti-inflammatory, zAntipyretic, zand z Analgesic zAgents
z Chapter z37: z Principles zof z Antimicrobial z Therapy
Chapter z 38: z Cell z Wall z Inhibitors
Chapter z 39: z Protein z Synthesis z Inhibitors
Chapter z40: zQuinolones, zFolic zAcid z Antagonists, z and z Urinary z Tract zAntiseptics
zChapter z41: zAntimycobacterial zDrugs
Chapter z42: zAntifungal zDrugs
zChapter z43: zAntiprotozoal zDrugs
zChapter z44: zAnthelmintic zDrugs
zChapter z45: zAntiviral zDrugs
Chapter z 46: z Anticancer z Drugs
Chapter z47: zImmunosuppressants
zChapter z48: zClinical zToxicology
,
,
, 3. The znurse zis zteaching za zpatient zwho zwill zbe zdischarged zhome zwithza zprescription zfor zan
enteric- zcoated ztablet. zWhich zstatement zby zthe zpatient z indicates zunderstanding zof zthe
z
teaching?
z
a. Izmay zcrush zthe ztablet zand zput zit zin zapplesauce zto zimprove zabsorption.
b. I zshould z consume zacidic zfoodszto zenhance zabsorption zof zthis zmedication.
c. I z should z expect z a zdelay zin zonset z of zthe zdrugs zeffects zafter ztaking zthe ztablet.
d. I zshould ztake zthis zmedication zwithzhigh-fat zfoodszto zimprove zits
action. zANS: zC
z
Enteric-coated ztablets zresist zdisintegration zin zthe zacidic zenvironment zof zthe zstomach zand
disintegrate zwhen zthey zreach zthe zsmall zintestine. zThere zis zusually zsome zdelay zin zonset zof
z
actions zafter ztaking zthese zmedications. zEnteric-coated ztablets zshould znot zbe zcrushed zor
z
chewed, zwhich zwould zalter zthe ztime zand zlocation zof zabsorption. zAcidic zfoods zwill znot
z
enhance zthe zabsorption zof zthe zmedication. zThe zpatient zshould znot zto zeat zhigh-fat zfood
z
before zingesting zan zenteric-coated ztablet, zbecause zhigh-fat zfoods zdecrease zthe zabsorption
z
rate.
z
DIF:zCOGNITIVE zLEVEL: zApplying z(Application) zREF: zdm z3
TOP: zNURSING zPROCESS: zNursing zIntervention
z
MSC:zNCLEX: zPhysiological zIntegrity: zPharmacological zand zParenteralzTherapies
4. A zpatient zwho zis znewly zdiagnosed zwith ztype z1 zdiabetes zmellitus zasks zwhy zinsulin
must zbe zgiven zby zsubcutaneous zinjection zinstead zof zbyzmouth. zThe znurse zwillzexplain zthat
z
this zis zbecause
z
a. absorption zis z diminished z byzthe zfirst-pass zeffects zin zthe zliver.
b. absorption zis zfaster zwhen zinsulin zis zgiven zsubcutaneously.
c. digestive zenzymes zin zthe zgastrointestinalztract zprevent zabsorption.
d. the zoral zformzis zless zpredictablezwith zmore zadverse
effects. zANS: zC
z
Insulin, zgrowth zhormones, zand zother zprotein-based zdrugs zare zdestroyed zin zthe zsmall
intestine zby zdigestive zenzymes zand zmust zbe zgiven zparenterally. zBecause zinsulin zis
z
destroyed zby zdigestive zenzymes, zit zwould znot zmake zit zto zthe zliver zfor zmetabolism zwithza
z
first-pass zeffect.zSubcutaneous ztissue zhas zfewer zblood zvessels, zso zabsorption zis zslower zin
z
such ztissue. zInsulin zis zgiven zsubcutaneously zbecause zit zis zdesirable zto zhave zit zabsorb
z
slowly.
z
DIF:zCOGNITIVE zLEVEL:zUnderstanding z(Comprehension) zREF: zdm z3
