Peptic Ulcer Disease (PUD) UPDATED
Exam Questions and CORRECT Answers
what are the 2 cells of the Gastric Gland? - CORRECT ANSWER - Parietal cells
Mucoid cells
What do parietal cells do? - CORRECT ANSWER - Produce and secrete HCl
Primary site of action for many acid-controller drugs
What do mucoid cells do? - CORRECT ANSWER - Mucus-secreting cells (surface epithelial
cells)
Provide a protective mucous coat
Protect against self-digestion by HCl
What is Hydrochloric Acid (HCl) Secretion stimulated by? - CORRECT ANSWER - Large
fatty meals
Excessive amounts of alcohol
Emotional stress
Why is stomach acid good? - CORRECT ANSWER - High acidity helps absorption and is
antimicrobial
Helps stimulate digestive enzymes
Helps absorb iron and B12
KILLs bacteria thats ingested
Why is stomach acid bad? - CORRECT ANSWER - If it splashes up the esophagus it can
cause
Heartburn pain/ Decrease QOL
Can damage the lining of the esophagus
, Heartburn
Esophagitis
Barrets esophogus
Stricures (scar tissue)
dental erosion
What are risk factors of PUD? - CORRECT ANSWER - Infection w H. Pyolri
Meds: Steroids, NSAIDS
Lifestyle: Stress/Smoking / ETOH
Family hx
What are some Non-Endoscopic test for H.Pylori? - CORRECT ANSWER - 1) Urea breath
test
Stop PPIs 2 weeks before test
2) Stool fecal antigen test
What are some tx options for H.Pylori? - CORRECT ANSWER - Infection will remain active
if not treated / high reoccurrence rate of ulcers
Acid-reducing medications have to little to no effect
1) Antibiotics, 2+
2) Proton pump inhibitor (PPI)
3) Bismuth compounds
How will the RN know the Peptic ulcers are getting worse? - CORRECT ANSWER -
bleeding ulcers= loss conciousness, vomit blood, pale, decrease BP, tachycardia
Bleeeding into peritoneal cavity= increase WBC count, vomit bile
What are the Treatment goals of PUD? - CORRECT ANSWER - Combination of lifestyle
changes and pharmacotherapy
Exam Questions and CORRECT Answers
what are the 2 cells of the Gastric Gland? - CORRECT ANSWER - Parietal cells
Mucoid cells
What do parietal cells do? - CORRECT ANSWER - Produce and secrete HCl
Primary site of action for many acid-controller drugs
What do mucoid cells do? - CORRECT ANSWER - Mucus-secreting cells (surface epithelial
cells)
Provide a protective mucous coat
Protect against self-digestion by HCl
What is Hydrochloric Acid (HCl) Secretion stimulated by? - CORRECT ANSWER - Large
fatty meals
Excessive amounts of alcohol
Emotional stress
Why is stomach acid good? - CORRECT ANSWER - High acidity helps absorption and is
antimicrobial
Helps stimulate digestive enzymes
Helps absorb iron and B12
KILLs bacteria thats ingested
Why is stomach acid bad? - CORRECT ANSWER - If it splashes up the esophagus it can
cause
Heartburn pain/ Decrease QOL
Can damage the lining of the esophagus
, Heartburn
Esophagitis
Barrets esophogus
Stricures (scar tissue)
dental erosion
What are risk factors of PUD? - CORRECT ANSWER - Infection w H. Pyolri
Meds: Steroids, NSAIDS
Lifestyle: Stress/Smoking / ETOH
Family hx
What are some Non-Endoscopic test for H.Pylori? - CORRECT ANSWER - 1) Urea breath
test
Stop PPIs 2 weeks before test
2) Stool fecal antigen test
What are some tx options for H.Pylori? - CORRECT ANSWER - Infection will remain active
if not treated / high reoccurrence rate of ulcers
Acid-reducing medications have to little to no effect
1) Antibiotics, 2+
2) Proton pump inhibitor (PPI)
3) Bismuth compounds
How will the RN know the Peptic ulcers are getting worse? - CORRECT ANSWER -
bleeding ulcers= loss conciousness, vomit blood, pale, decrease BP, tachycardia
Bleeeding into peritoneal cavity= increase WBC count, vomit bile
What are the Treatment goals of PUD? - CORRECT ANSWER - Combination of lifestyle
changes and pharmacotherapy
