NURS 5334 Antimicrobial Review
Study online at https://quizlet.com/_ad2tjf
1. Gram positive organisms Staph, Strep, Enterococcus
2. 1st line Treatment of Gram Penicillins
positive
3. 2nd line treatment of Cephalosporins: 3rd generation (cefdinir, cefuroxime) Macrolides:
Gram positive with Peni- if anaphylactic (azithromycin, clarithromycin)
cillin Allergy
4. AOM and sinusitis organ- Haemophilus influenzas, Moraxella catarrhalis, Streptococcus
isms pheumoniae
5. 1st line tx for AOM high dose amoxicillin 5-10 days
6. AOM pain Ibuprofen, acetaminophen
7. for Antibiotic resistant amoxicillin- clavulanate or ceftriaxone
AOM
8. AE with clavulante diarrhea
9. Renders PCNs G and V in- beta-lactamases
active
10. to Tx Step and AOM Ampicillin, amoxicillin
11. DOC for PCN allergies Macrolides
12. Narrow spectrum PCNs re- Oxacillin, Nafcillin, dicloxacillin,
sistant to penicillinase en-
zymes
13. extended spectrum an- Piperacillin/tazobactam
tipseudomonal PCN
, NURS 5334 Antimicrobial Review
Study online at https://quizlet.com/_ad2tjf
14. Not affected by beta lacta- oxacillin, nafcillin, dicloxacillin
mase bacteria
15. Piperacillin (given with effective against pseudomonas, Enterobacter, Bacteroides fragilis
tazobactam)=Zosyn and klebsiella. is not given alone.
16. Beta lactamase inhibitors never given alone: clavulanic acid, tazobactam, sulbactam no MRSA
coverage
17. piperacillin/tazobactam effective against pseudomonas
18. amoxicillin/clavulanic acid ears, lungs, sinus, skin, and urinary tract. used to treat infections
caused by beta-lactamase producing organisms.
19. Beta lactamase inhibitors ampicillin/sulbactam; amoxicillin/clavulanic acid;
combined drugs Piperacillin/tazobactam NO:MRSA coverage
20. Cephalosporins most widely used, has a beta lactam ring
21. 1st generation presurgical prophylaxis, gram-positive,
Cephalosporins
22. 2nd generation mostly gram-positive. cefoxitin-(anaerobic Bacteroides fragilis),ce-
cephalosporins furoxime (URI, pneumonia from h flu, pneumococci and staph)
some beta-lactamase cover
23. 3rd generation meningitis=penetrates the CSF. good Gram negative aerobe cover-
cephalosporins age. no pseudomonas or enterococcus activity.
24. 4th generation pseudomonas and hospital acquired infections; Cef-
cephalosporins taolozane/tazobactam; cefepime
25. 5th generation
cephalosporins
Study online at https://quizlet.com/_ad2tjf
1. Gram positive organisms Staph, Strep, Enterococcus
2. 1st line Treatment of Gram Penicillins
positive
3. 2nd line treatment of Cephalosporins: 3rd generation (cefdinir, cefuroxime) Macrolides:
Gram positive with Peni- if anaphylactic (azithromycin, clarithromycin)
cillin Allergy
4. AOM and sinusitis organ- Haemophilus influenzas, Moraxella catarrhalis, Streptococcus
isms pheumoniae
5. 1st line tx for AOM high dose amoxicillin 5-10 days
6. AOM pain Ibuprofen, acetaminophen
7. for Antibiotic resistant amoxicillin- clavulanate or ceftriaxone
AOM
8. AE with clavulante diarrhea
9. Renders PCNs G and V in- beta-lactamases
active
10. to Tx Step and AOM Ampicillin, amoxicillin
11. DOC for PCN allergies Macrolides
12. Narrow spectrum PCNs re- Oxacillin, Nafcillin, dicloxacillin,
sistant to penicillinase en-
zymes
13. extended spectrum an- Piperacillin/tazobactam
tipseudomonal PCN
, NURS 5334 Antimicrobial Review
Study online at https://quizlet.com/_ad2tjf
14. Not affected by beta lacta- oxacillin, nafcillin, dicloxacillin
mase bacteria
15. Piperacillin (given with effective against pseudomonas, Enterobacter, Bacteroides fragilis
tazobactam)=Zosyn and klebsiella. is not given alone.
16. Beta lactamase inhibitors never given alone: clavulanic acid, tazobactam, sulbactam no MRSA
coverage
17. piperacillin/tazobactam effective against pseudomonas
18. amoxicillin/clavulanic acid ears, lungs, sinus, skin, and urinary tract. used to treat infections
caused by beta-lactamase producing organisms.
19. Beta lactamase inhibitors ampicillin/sulbactam; amoxicillin/clavulanic acid;
combined drugs Piperacillin/tazobactam NO:MRSA coverage
20. Cephalosporins most widely used, has a beta lactam ring
21. 1st generation presurgical prophylaxis, gram-positive,
Cephalosporins
22. 2nd generation mostly gram-positive. cefoxitin-(anaerobic Bacteroides fragilis),ce-
cephalosporins furoxime (URI, pneumonia from h flu, pneumococci and staph)
some beta-lactamase cover
23. 3rd generation meningitis=penetrates the CSF. good Gram negative aerobe cover-
cephalosporins age. no pseudomonas or enterococcus activity.
24. 4th generation pseudomonas and hospital acquired infections; Cef-
cephalosporins taolozane/tazobactam; cefepime
25. 5th generation
cephalosporins
