ATI Pharmacology RN Exam Questions
and Answers(A+ Solution guide) 2025
New Update
Digoxin (lanoxin) SE - Answers -✔✔ blurred/double vision
Guaifenesin SE - Answers -✔✔ can cause drowsiness
Estrogen (premarin) SE - Answers -✔✔ ↑ risk of Thromboembolism with s/s: SOB,
severe headache, vomiting, sudden acute pain in the calves, legs, chest, abdomen.
Doxepin (Sinequan) [anticholinergic] SE - Answers -✔✔ urinary retension, constipation,
drying of nasal/oral secretons, ↑HR
Albuterol (Proventil) [sympathomimetic/ adrenergic beta-2 agonist] Contraindicated -
Answers -✔✔ with MAOIs (can↑ action of albuterol and → HTN crisis); β-blockers can
inhibit the therapeutic effects Use: invert canister, shake before use, rinse mouth after
use, w/new inhaler perform test spray
Levothryoxine (T4) Indication - Answers -✔✔ hypothyroidism RT dysfxn of
hypothalamus, pituitary, or thyroid gland
Cephalosporins (Keflex) - Answers -✔✔ allergy to cephalosporins is considered a
precaution for taking penicillins
Phenobarbital [Barbiturates]; interventions for anticonvulsant therapy - Answers -✔✔
assess for resp. depression, excess sedation from toxic effects, IV at < 50mg/min, avoid
extravasation (alkaline→skin damage)
Sumatriptan (Imitrex) use - Answers -✔✔ when migraine symptoms appear and again in
1 hr if symptoms persist
Route—fastest/most effective - Answers -✔✔ intravenous
Narcan [opioid antagonist] - Answers -✔✔ therapeutic action: improvement of
respiratory rate
Baclofen (Lioresal) Therapeutic action - Answers -✔✔ ↓ frequency & severity of muscle
spasms
Erythromycin (Erythrocin) [macrolide] SE - Answers -✔✔ liver toxicity
, What do need to avoid when taking Spironolactone (Aldactone) [K sparing diuretic] -
Answers -✔✔ foods w/ ↑ K such as salt substitutes
Chloroquine phosphate (Aralen): Indication - Answers -✔✔ malaria prevention; Use:
take weekly starting 1 week before departure and continued for 4 weeks after return.
Heparin (anticoagulant) Use - Answers -✔✔ w/alteplase for acute MI
Warfarin (Coumadin) Use - Answers -✔✔ long-term prophylaxis of thrombosis
[antidote—Vit K]
Clopidogrel (Plavix) Use - Answers -✔✔ reduce long-term risk of clotting w/
atherosclerosis and recent MI of CVA
Alteplase (Activase) [antithrombolytic] Use - Answers -✔✔ Acute MI/CVA (has short
half-life)
Methylphenidate (Concerta) Use - Answers -✔✔ marcolepsy Precaution: avoid caffeine
use
Testosterone IM use - Answers -✔✔ If use to correct delayed puberty→assess bone
maturation with bi-annual x-rays of hand and wrist; monitor liver function (can ↑
hypoglycemia, potentiate sleep apnea, exacerbate heart failure due to fluid retention.
Diphenoxylate & Atropine (Lomotil) Caution - Answers -✔✔ With Renal impairment ↓
elimination of atropine → ↑ anticholinergic effects of atropine like confusion
Loperamide (Imodium) use - Answers -✔✔ anti-diarrheal (poorly absorbed from GI tract;
difficulty crossing the blood-brain barrier)
Methylcellulose (Citrucel) use - Answers -✔✔ bulk-forming agent with minimal Side
Effects (SE)
Psyllium (Metamucil) use - Answers -✔✔ bulk-forming agent with minimal Side Effects
(SE)
Acetazolamide (Diamox) [diuretic] indication - Answers -✔✔ edema, epilepsy, acute
mountain sickness, glaucoma (↓ intraocular pressure by ↓ amount of aqueous humor in
the eye) Contra: allergy to sulfonamides
Metoprolol (Lopressor) [β-blocker] use and side effects - Answers -✔✔ Hold dose for
dyspnea (sign of exacerbation of CHF) Propanolol (Inderal) Use. Dysrhythmia, HTN,
angina; SE: bronchoconstriction/bronchospasm; can block glyconeogenesis
and Answers(A+ Solution guide) 2025
New Update
Digoxin (lanoxin) SE - Answers -✔✔ blurred/double vision
Guaifenesin SE - Answers -✔✔ can cause drowsiness
Estrogen (premarin) SE - Answers -✔✔ ↑ risk of Thromboembolism with s/s: SOB,
severe headache, vomiting, sudden acute pain in the calves, legs, chest, abdomen.
Doxepin (Sinequan) [anticholinergic] SE - Answers -✔✔ urinary retension, constipation,
drying of nasal/oral secretons, ↑HR
Albuterol (Proventil) [sympathomimetic/ adrenergic beta-2 agonist] Contraindicated -
Answers -✔✔ with MAOIs (can↑ action of albuterol and → HTN crisis); β-blockers can
inhibit the therapeutic effects Use: invert canister, shake before use, rinse mouth after
use, w/new inhaler perform test spray
Levothryoxine (T4) Indication - Answers -✔✔ hypothyroidism RT dysfxn of
hypothalamus, pituitary, or thyroid gland
Cephalosporins (Keflex) - Answers -✔✔ allergy to cephalosporins is considered a
precaution for taking penicillins
Phenobarbital [Barbiturates]; interventions for anticonvulsant therapy - Answers -✔✔
assess for resp. depression, excess sedation from toxic effects, IV at < 50mg/min, avoid
extravasation (alkaline→skin damage)
Sumatriptan (Imitrex) use - Answers -✔✔ when migraine symptoms appear and again in
1 hr if symptoms persist
Route—fastest/most effective - Answers -✔✔ intravenous
Narcan [opioid antagonist] - Answers -✔✔ therapeutic action: improvement of
respiratory rate
Baclofen (Lioresal) Therapeutic action - Answers -✔✔ ↓ frequency & severity of muscle
spasms
Erythromycin (Erythrocin) [macrolide] SE - Answers -✔✔ liver toxicity
, What do need to avoid when taking Spironolactone (Aldactone) [K sparing diuretic] -
Answers -✔✔ foods w/ ↑ K such as salt substitutes
Chloroquine phosphate (Aralen): Indication - Answers -✔✔ malaria prevention; Use:
take weekly starting 1 week before departure and continued for 4 weeks after return.
Heparin (anticoagulant) Use - Answers -✔✔ w/alteplase for acute MI
Warfarin (Coumadin) Use - Answers -✔✔ long-term prophylaxis of thrombosis
[antidote—Vit K]
Clopidogrel (Plavix) Use - Answers -✔✔ reduce long-term risk of clotting w/
atherosclerosis and recent MI of CVA
Alteplase (Activase) [antithrombolytic] Use - Answers -✔✔ Acute MI/CVA (has short
half-life)
Methylphenidate (Concerta) Use - Answers -✔✔ marcolepsy Precaution: avoid caffeine
use
Testosterone IM use - Answers -✔✔ If use to correct delayed puberty→assess bone
maturation with bi-annual x-rays of hand and wrist; monitor liver function (can ↑
hypoglycemia, potentiate sleep apnea, exacerbate heart failure due to fluid retention.
Diphenoxylate & Atropine (Lomotil) Caution - Answers -✔✔ With Renal impairment ↓
elimination of atropine → ↑ anticholinergic effects of atropine like confusion
Loperamide (Imodium) use - Answers -✔✔ anti-diarrheal (poorly absorbed from GI tract;
difficulty crossing the blood-brain barrier)
Methylcellulose (Citrucel) use - Answers -✔✔ bulk-forming agent with minimal Side
Effects (SE)
Psyllium (Metamucil) use - Answers -✔✔ bulk-forming agent with minimal Side Effects
(SE)
Acetazolamide (Diamox) [diuretic] indication - Answers -✔✔ edema, epilepsy, acute
mountain sickness, glaucoma (↓ intraocular pressure by ↓ amount of aqueous humor in
the eye) Contra: allergy to sulfonamides
Metoprolol (Lopressor) [β-blocker] use and side effects - Answers -✔✔ Hold dose for
dyspnea (sign of exacerbation of CHF) Propanolol (Inderal) Use. Dysrhythmia, HTN,
angina; SE: bronchoconstriction/bronchospasm; can block glyconeogenesis
