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Test bank for Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, 8th Edition by Nader Rifai, PhD Chapters 1 - 49

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Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8 th Edition Test Bank Table of contents: I. Principles Of Laboratory Medicine Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques Chapter 3. Clinical Evaluation of Methods Chapter 4. Evidence-Based Laboratory Medicine Chapter 5. Establishment and Use of Reference Values Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables Chapter 7. Quality Management II. Analytical Techniques And Instrumentation Chapter 8. Principles of Basic Techniques and Laboratory Safety Chapter 9. Optical Techniques Chapter 10. Electrochemistry and Chemical Sensors Chapter 11. Electrophoresis Chapter 12. Chromatography Chapter 13. Mass Spectrometry Chapter 14. Enzyme and Rate Analyses Chapter 15. Immunochemical Techniques Chapter 16 Automation Chapter 17. Point-of-Care Instrumentation III. Analytes Chapter 18. Amino Acids, Peptides, and Proteins Chapter 19. Serum Enzymes Chapter 20. Tumor Markers and Cancer Genes Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid Chapter 22. Carbohydrates Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors Chapter 24. Electrolytes and Blood Gases Chapter 25. Hormones Chapter 26. Catecholamines and Serotonin Chapter 27. Vitamins, Trace Elements, Nutritional Assessment Chapter 28. Hemoglobin, Iron, and Bilirubin Chapter 29. Porphyrins and Porphyrias Chapter 30. Therapeutic Drugs and Their Management Chapter 31. Clinical Toxicology Chapter 32. Toxic Metals IV. Pathophysiology Chapter 33. Diabetes Chapter 34. Cardiovascular Disease Chapter 35. Kidney Disease Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism Chapter 37. Liver Disease Chapter 38. Gastrointestinal and Pancreatic Diseases Chapter 39. Disorders of Bone and Mineral Metabolism Chapter 40. Disorders of the Pituitary Gland Chapter 41. Disorders of the Adrenal Cortex Chapter 42. Thyroid Disorders Chapter 43. Reproduction-Related Disorders Chapter 44. Pregnancy and Prenatal Testing Chapter 45. Newborn Screening and Inborn Errors of Metabolism Chapter 46. Pharmacogenetics V. Molecular Diagnostics Chapter 47. Principles of Molecular Biology Chapter 48. Nucleic Acid Techniques and Applications Chapter 49. Genomes and Nucleic Acid Alterations Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine TestBank MULTIPLE CHOICE 1. An individual working in a clinical chemistry laboratory is married to a sales representative who works for a company that sells chemistry laboratory supplies. When the laboratory manager requests a list of needed supplies, cost of supplies, and vendors, this individual only recommends the spouse’s company as the vendor. This is considered to be a(n): a. accounting issue. b. possible conflict of interest. c. maintenance of confidentiality issue. d. problem with resource allocation. ANS: B Concern has been raised over the interrelationships between practitioners in the medical field and commercial suppliers of drugs, devices, equipment, etc., to the medical profession. Similarly, relationships have been scrutinized between clinical laboratorians and manufacturers and providers of diagnostic equipment and supplies. These concerns led the National Institutes of Health (NIH) in 1995 to require official institutional review of financial disclosure by researchers and management of situations in which disclosure indicates potential conflicts of interest. DIF: 1 REF: Page 4-5 OBJ: 6 | 7

Content preview

Test bank for Tietz Fundamentals of Clinical Chemistry
and Molecular Diagnostics,
8th Edition by Nader Rifai, PhD
Chapters 1 - 49

,TietzeFundamentalseofeClinicaleChemistryeandeMoleculareDiagnosticse8the EditioneTesteBank
Tableeofecontents:
I.ePrincipleseOfeLaboratoryeMedicine
Chaptere1.eClinicaleChemistry,eMoleculareDiagnostics,eandeLaboratoryeMedicine
Chaptere2.eSelectioneandeAnalyticaleEvaluationeofeMethodse—eWitheStatisticaleTechniques
Chaptere3.eClinicaleEvaluationeofeMethods
Chaptere4.eEvidence-BasedeLaboratoryeMedicine
Chaptere5.eEstablishmenteandeUseeofeReferenceeValues
Chaptere6.eSpecimeneCollection,eProcessing,eandeOtherePreanalyticaleVariables
Chaptere7.eQualityeManagement
II.eAnalyticaleTechniqueseAndeInstrumentation
Chaptere8.ePrincipleseofeBasiceTechniqueseandeLaboratoryeSafety
Chaptere9.eOpticaleTechniques
Chaptere10.eElectrochemistryeandeChemicaleSensors
Chaptere11.eElectrophoresis
Chaptere12.eChromatography
Chaptere13.eMasseSpectrometry
Chaptere14.eEnzymeeandeRateeAnalyses
Chaptere15.eImmunochemicaleTechniques
Chaptere16eAutomation
Chaptere17.ePoint-of-CareeInstrumentation
III.e Analytes
Chaptere18.eAminoeAcids,ePeptides,eandeProteins
Chaptere19.eSerumeEnzymes
Chaptere20.eTumoreMarkerseandeCancereGenes
Chaptere21.eKidneyeFunctioneTestse—eCreatinine,eGFR,eUrea,eandeUriceAcid
Chaptere22.eCarbohydrates
Chaptere23.eLipids,eLipoproteins,eApolipoproteins,eandeOthereCardiaceRiskeFactors
Chaptere24.eElectrolyteseandeBloodeGases
Chaptere25.eHormones
Chaptere26.e CatecholamineseandeSerotonin
Chaptere27.e Vitamins,eTraceeElements,eNutritionaleAssessment
Chaptere28.eHemoglobin,eIron,eandeBilirubin
Chaptere29.ePorphyrinseandePorphyrias
Chaptere30.eTherapeuticeDrugseandeTheireManagement
Chaptere31.eClinicaleToxicology
Chaptere32.e ToxiceMetals
IV.e Pathophysiology
Chaptere33.eDiabetes

,Chaptere34.e CardiovasculareDisease
Chaptere35.eKidneyeDisease
Chaptere36.e PhysiologyeandeDisorderseofeWater,eElectrolyte,eandeAcid-BaseeMetabolism
Chaptere37.e LivereDisease
Chaptere38.e GastrointestinaleandePancreaticeDiseases
Chaptere39.e DisorderseofeBoneeandeMineraleMetabolism
Chaptere40.e DisorderseofetheePituitaryeGland
Chaptere41.e DisorderseofetheeAdrenaleCortex
Chaptere42.e ThyroideDisorders
Chaptere43.e Reproduction-RelatedeDisorders
Chaptere44.e PregnancyeandePrenataleTesting
Chaptere45.e NewborneScreeningeandeInborneErrorseofeMetabolism
Chaptere46.ePharmacogenetics
V.e MoleculareDiagnostics
Chaptere47.ePrincipleseofeMoleculareBiology
Chaptere48.eNucleiceAcideTechniqueseandeApplications
Chaptere49.eGenomeseandeNucleiceAcideAlterations

, Chaptere01:eClinicaleChemistry,eMoleculareDiagnostics,eandeLaboratoryeMedicineeTesteBank


MULTIPLEeCHOICE

1. Aneindividualeworkingeineaeclinicalechemistryelaboratoryeisemarriedetoeaesaleserepresentativeew
hoeworkseforeaecompanyethatesellsechemistryelaboratoryesupplies.eWhenetheelaboratoryemaneager
erequestseaelisteofeneededesupplies,ecosteofesupplies,eandevendors,ethiseindividualeonlyrecoemmen

dsetheespouse’secompanyeasetheevendor.eThiseiseconsideredetoebeea(n):
a. accountingeissue.
b. possibleeconflicteofeinterest.
c. maintenanceeofeconfidentialityeissue.
d. problemewitheresourceeallocation.
ANS:e B
Concernehasebeeneraisedeoveretheeinterrelationshipsebetweenepractitionerseinetheemedicalefieldean
decommercialesupplierseofedrugs,edevices,eequipment,eetc.,etoetheemedicaleprofession.
Similarly,erelationshipsehaveebeenescrutinizedebetweeneclinicalelaboratorianseandemanufacturerese
andeproviderseofediagnosticeequipmenteandesupplies.eTheseeconcernseledetheeNationaleInstituteeseo
feHealthe(NIH)eine1995etoerequireeofficialeinstitutionalerevieweofefinancialedisclosureebyereseearche
rseandemanagementeofesituationseinewhichedisclosureSindicatesepotentialconflictseofeintereest.

DIF: 1 REF:e e Pagee4-5 OBJ:e 6e|e7

2. Aepatientevisitseherephysicianestatingethatehereprescribedepainkillereisenoteworkingetoereduceetehee
painefollowingehererecentesurgery.eAefriendeofetheSpatienteclaimsethatetheesameepainkiller“ework
edewonders”etoereduceeherepaineafteretheesameesurgery.eTheephysicianestatesethatetheedifeferencee
inetheeeffecteofetheedrugemightebeecausedeby
,ewhicheisestudiedeinepharmacogenetics.
a. epidemiology
b. aneinheritededisease
c. aeconflicteofeinterest
d. aegeneticevariationeinedrug-metabolizingeenzymes
ANS:e D
Pharmacogeneticseisetheestudyeofetheegeneticevariationeofedrugemetabolismebetweeniendividual
s.

DIF: 1 REF:e e Pagee3 OBJ:e 1

3. Johneworkseineaemolecularediagnosticselaboratoryeandereceiveseaebloodesampleethatehasetheenea
meeofeaecloseefriendeprintedSonetheebar-
codedelabel.eTheegeneticetestethateiseorderedeonethefriend’sesampleewouldeprovideediagnosticeinfor
mationeabouteaedisorderethatehaseaepooreprognosis,eandetheetesteiseusuallyeperformedebyeJohn.eHeea
skseaefelloweemployeeetoeanalyzetheesampleeforehimeandenotedivulgeetheeresults.eThiseethicaleissu
eSconcerns:
a. confidentialityeofepatientegeneticeandemedicaleinformation.
b. aeconflicteofeinterest.
c. resourceeallocation.
d. diagnosticeaccuracy.

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