Forensic Toxicology Final Exam 115
complete solutions.
Forensic Toxicology Final Exam 115
complete solutions.
Jean Stas - ANSWER Isolated nicotine from organ tissues
Robert Borkenstein - ANSWER With Rolla Harger, developed the drunkometer. The precursor to the
breathalyzer
Matthieu Orfila - ANSWER Father of toxicology; attempted to categorize poisons in "Traite de Poisons"
Paracelsus - ANSWER "The dose determines the poison"
James March - ANSWER Inventor of the test for arsenic
Alexander Gettler - ANSWER Father of American Toxicology
Peripheral blood - ANSWER This sample will give better (more interpretable) results
What is the biggest problem for DFSA (drug facilitated sexual assault cases) - ANSWER 24-48 hour cutoff
True or False: toxicological postmortem case analysis is very different than in DUI cases - ANSWER False
Tox Lab A uses predominantly LLE to confirm positive cases (not SPE). What could be two positive
reasons for its decision? - ANSWER Cheaper and wide variety choice of solvents
Tox Lab B uses predominately SPE to confirm positive cases (not LLE). What could be two positive
reasons for its decision? - ANSWER More selective and better recovery
, Forensic Toxicology Final Exam 115
complete solutions.
What is a DRE officer? - ANSWER a police officer with special training to detect a class of drugs
2 examples of phase 1 metabolism - ANSWER hydroxylation and hydrolysis
A compound that exhibits zero order kinetics - ANSWER alcohol
Acetylation is an example of a phase_______ process - ANSWER 2
As an acidic drug travels down the length of the small intestine, the amount of drug in the non-ionized
form would be expected to... - ANSWER decrease
low volume of distribution - ANSWER the amount of fluid that a drug would distribute into if all stayed in
the blood
intravenous - ANSWER entire dose get absorbed into the bloodstream
epoxide formation of a drug is an example of phase _____ metabolism - ANSWER 1
morphine glucuronide - ANSWER has an active metabolite
Constant fraction of the dose eliminated over time - ANSWER 1st order kinetics
codeine - ANSWER could produce a positive test for morphine
lipophilic drugs - ANSWER higher volume of distribution than a hydrophilic one
4 phases of pharmacokinetics - ANSWER absorption, distribution, metabolism, elimination
complete solutions.
Forensic Toxicology Final Exam 115
complete solutions.
Jean Stas - ANSWER Isolated nicotine from organ tissues
Robert Borkenstein - ANSWER With Rolla Harger, developed the drunkometer. The precursor to the
breathalyzer
Matthieu Orfila - ANSWER Father of toxicology; attempted to categorize poisons in "Traite de Poisons"
Paracelsus - ANSWER "The dose determines the poison"
James March - ANSWER Inventor of the test for arsenic
Alexander Gettler - ANSWER Father of American Toxicology
Peripheral blood - ANSWER This sample will give better (more interpretable) results
What is the biggest problem for DFSA (drug facilitated sexual assault cases) - ANSWER 24-48 hour cutoff
True or False: toxicological postmortem case analysis is very different than in DUI cases - ANSWER False
Tox Lab A uses predominantly LLE to confirm positive cases (not SPE). What could be two positive
reasons for its decision? - ANSWER Cheaper and wide variety choice of solvents
Tox Lab B uses predominately SPE to confirm positive cases (not LLE). What could be two positive
reasons for its decision? - ANSWER More selective and better recovery
, Forensic Toxicology Final Exam 115
complete solutions.
What is a DRE officer? - ANSWER a police officer with special training to detect a class of drugs
2 examples of phase 1 metabolism - ANSWER hydroxylation and hydrolysis
A compound that exhibits zero order kinetics - ANSWER alcohol
Acetylation is an example of a phase_______ process - ANSWER 2
As an acidic drug travels down the length of the small intestine, the amount of drug in the non-ionized
form would be expected to... - ANSWER decrease
low volume of distribution - ANSWER the amount of fluid that a drug would distribute into if all stayed in
the blood
intravenous - ANSWER entire dose get absorbed into the bloodstream
epoxide formation of a drug is an example of phase _____ metabolism - ANSWER 1
morphine glucuronide - ANSWER has an active metabolite
Constant fraction of the dose eliminated over time - ANSWER 1st order kinetics
codeine - ANSWER could produce a positive test for morphine
lipophilic drugs - ANSWER higher volume of distribution than a hydrophilic one
4 phases of pharmacokinetics - ANSWER absorption, distribution, metabolism, elimination
