TESTBANK 7
RUBIN'S PATHOLOGY: CLIN
7 7
ICOPATHOLOGIC FOUNDATI 7
ONS OF MEDICINE 7 7
7th Edition By David S. Strayer, Emanuel Rubin
7 7 7 7 7 7 7
TESTBANK 7
,Test7Bank7Rubin's7Pathology:7Clinicopathologic7Foundations7of7Medicine77th7 Edition
Table7of7Contents:
Chapter71:7Cell7Adaptation,7Injury7and7Death
Chapter72:7Inflammation
Chapter73:7Repair,7Regeneration7and7Fibrosis
Chapter74:7Immunopathology
Chapter75:7Neoplasia
Chapter76:7Developmental7and7Genetic7Diseases
Chapter77:7Hemodynamic7Disorders
Chapter78:7Environmental7and7Nutritional7Pathology
Chapter79:7Infectious7and7Parasitic7Diseases
Section7II:7Pathogenesis7of7Systemic7Conditions7Expandable7section
Chapter710:7Aging
Chapter711:7Systemic7Autoimmune7Diseases
Chapter712:7Sepsis
Chapter713:7Obesity7and7Diabetes7Mellitus
Chapter714:7The7Pathology7of7Pregnancy
Chapter715:7The7Amyloidoses
Section7III:7Diseases7of7Individual7Organ7SystemsExpandable7section
Chapter716:7Blood7Vessels
Chapter717:7The7Heart
Chapter718:7The7Respiratory7System
Chapter719:7The7Gastrointestinal7Tract
Chapter720:7The7Liver7and7Biliary7System
Chapter721:7The7Pancreas
Chapter722:7The7Kidney
Chapter723:7The7Lower7Urinary7Tract7and7Male7Reproductive7System
Chapter724:7The7Female7Reproductive7System7and7Peritoneum
Chapter725:7The7Breast
Chapter726:7Hematopathology
Chapter727:7The7Endocrine7System
Chapter728:7The7Skin
Chapter729:7The7Head7and7Neck
Chapter730:7Bones,7Joints7and7Soft7Tissue
Chapter731:7Skeletal7Muscle7and7Peripheral7Nervous7System
Chapter732:7The7Central7Nervous7System
Chapter733:7The7Eye
Chapter734:7Forensic7Pathology
,Rubin's7Pathology:7Clinicopathologic7Foundations7of7Medicine7Chapte
r71:7Cell7Adaptation,7Injury7and7Death
Ischemia7and7other7toxic7injuries7increase7the7accumulation7of7intracellular7calcium7as7a7result7of:
1.
A) release7of7stored7calcium7from7the7mitochondria.
B) improved7intracellular7volume7regulation.
C) decreased7influx7across7the7cell7membrane.
D) attraction7of7calcium7to7fatty7infiltrates.
The7patient7is7found7to7have7liver7disease,7resulting7in7the7removal7of7a7lobe7of7his7liver.7Adapt
2. ation7to7the7reduced7size7of7the7liver7leads7to7_ of7the7remaining7liver7cells.
A) metaplasia
B) organ7atrophy
C) compensatory7hyperplasia
D) physiologic7hypertrophy
A7person7eating7peanuts7starts7choking7and7collapses.7His7airway7obstruction7is7partially7cl
eared,7but7he7remains7hypoxic7until7he7reaches7the7hospital.7The7prolonged7cell7hypoxia7ca
3. used7a7cerebral7infarction7and7resulting _7in7the7brain.
A) caspase7activation
B) coagulation7necrosis
C) rapid7phagocytosis
D) protein7p537deficiency
Bacteria7and7viruses7cause7cell7damage7by
4. ,7which7is7unique7from7the7intracellular7
damage7caused7by7other7injurious7agents.
A) disrupting7the7sodium/potassium7ATPase7pump
B) interrupting7oxidative7metabolism7processes
C) replicating7and7producing7continued7injury
D) decreasing7protein7synthesis7and7function
The7patient7has7a7prolonged7interruption7in7arterial7blood7flow7to7his7left7kidney,7causing7hypoxic
5. 7cell7injury7and7the7release7of7free7radicals.7Free7radicals7damage7cells7by:
A) destroying7phospholipids7in7the7cell7membrane.
B) altering7the7immune7response7of7the7cell.
C) disrupting7calcium7storage7in7the7cell.
, D) inactivation7of7enzymes7and7mitochondria.
6. Injured7cells7have7impaired7flow7of7substances7through7the7cell7membrane7as7a7result7of:
A) increased7fat7load.
B) altered7permeability.
C) altered7glucose7utilization.
D) increased7surface7receptors.
7. Reversible7adaptive7intracellular7responses7are7initiated7by:
A) stimulus7overload.
B) genetic7mutations.
C) chemical7messengers.
D) mitochondrial7DNA.
8. Injured7cells7become7very7swollen7as7a7result7of:
A) increased7cell7protein7synthesis.
B) altered7cell7volume7regulation.
C) passive7entry7of7potassium7into7the7cell.
D) bleb7formation7in7the7plasma7membrane.
A7diabetic7patient7has7impaired7sensation,7circulation,7and7oxygenation7of7his7feet.7He7steps7on7a7
piece7of7glass,7the7wound7does7not7heal,7and7the7area7tissue7becomes7necrotic.7The7necrotic7cell7
9. death7is7characterized7by:
A) rapid7apoptosis.
B) cellular7rupture.
C) shrinkage7and7collapse.
D) chronic7inflammation.
A799-year-
10. old7woman7has7experienced7the7decline7of7cell7function7associated7with7age.7A7group7of7theorie
s7of7cellular7aging7focus7on7programmed:
A) changes7with7genetic7influences.
B) elimination7of7cell7receptor7sites.
C) insufficient7telomerase7enzyme.
D) DNA7mutation7or7faulty7repair.
An789-year-
old7female7patient7has7experienced7significant7decreases7in7her7mobility7and7stamina7during7a73
-
11. week7hospital7stay7for7the7treatment7of7a7femoral7head7fracture.7Which7of7the7following7phenom
ena7most7likely7accounts7for7the7patients7decrease7in7muscle7function7that7underlies7her7reduced
RUBIN'S PATHOLOGY: CLIN
7 7
ICOPATHOLOGIC FOUNDATI 7
ONS OF MEDICINE 7 7
7th Edition By David S. Strayer, Emanuel Rubin
7 7 7 7 7 7 7
TESTBANK 7
,Test7Bank7Rubin's7Pathology:7Clinicopathologic7Foundations7of7Medicine77th7 Edition
Table7of7Contents:
Chapter71:7Cell7Adaptation,7Injury7and7Death
Chapter72:7Inflammation
Chapter73:7Repair,7Regeneration7and7Fibrosis
Chapter74:7Immunopathology
Chapter75:7Neoplasia
Chapter76:7Developmental7and7Genetic7Diseases
Chapter77:7Hemodynamic7Disorders
Chapter78:7Environmental7and7Nutritional7Pathology
Chapter79:7Infectious7and7Parasitic7Diseases
Section7II:7Pathogenesis7of7Systemic7Conditions7Expandable7section
Chapter710:7Aging
Chapter711:7Systemic7Autoimmune7Diseases
Chapter712:7Sepsis
Chapter713:7Obesity7and7Diabetes7Mellitus
Chapter714:7The7Pathology7of7Pregnancy
Chapter715:7The7Amyloidoses
Section7III:7Diseases7of7Individual7Organ7SystemsExpandable7section
Chapter716:7Blood7Vessels
Chapter717:7The7Heart
Chapter718:7The7Respiratory7System
Chapter719:7The7Gastrointestinal7Tract
Chapter720:7The7Liver7and7Biliary7System
Chapter721:7The7Pancreas
Chapter722:7The7Kidney
Chapter723:7The7Lower7Urinary7Tract7and7Male7Reproductive7System
Chapter724:7The7Female7Reproductive7System7and7Peritoneum
Chapter725:7The7Breast
Chapter726:7Hematopathology
Chapter727:7The7Endocrine7System
Chapter728:7The7Skin
Chapter729:7The7Head7and7Neck
Chapter730:7Bones,7Joints7and7Soft7Tissue
Chapter731:7Skeletal7Muscle7and7Peripheral7Nervous7System
Chapter732:7The7Central7Nervous7System
Chapter733:7The7Eye
Chapter734:7Forensic7Pathology
,Rubin's7Pathology:7Clinicopathologic7Foundations7of7Medicine7Chapte
r71:7Cell7Adaptation,7Injury7and7Death
Ischemia7and7other7toxic7injuries7increase7the7accumulation7of7intracellular7calcium7as7a7result7of:
1.
A) release7of7stored7calcium7from7the7mitochondria.
B) improved7intracellular7volume7regulation.
C) decreased7influx7across7the7cell7membrane.
D) attraction7of7calcium7to7fatty7infiltrates.
The7patient7is7found7to7have7liver7disease,7resulting7in7the7removal7of7a7lobe7of7his7liver.7Adapt
2. ation7to7the7reduced7size7of7the7liver7leads7to7_ of7the7remaining7liver7cells.
A) metaplasia
B) organ7atrophy
C) compensatory7hyperplasia
D) physiologic7hypertrophy
A7person7eating7peanuts7starts7choking7and7collapses.7His7airway7obstruction7is7partially7cl
eared,7but7he7remains7hypoxic7until7he7reaches7the7hospital.7The7prolonged7cell7hypoxia7ca
3. used7a7cerebral7infarction7and7resulting _7in7the7brain.
A) caspase7activation
B) coagulation7necrosis
C) rapid7phagocytosis
D) protein7p537deficiency
Bacteria7and7viruses7cause7cell7damage7by
4. ,7which7is7unique7from7the7intracellular7
damage7caused7by7other7injurious7agents.
A) disrupting7the7sodium/potassium7ATPase7pump
B) interrupting7oxidative7metabolism7processes
C) replicating7and7producing7continued7injury
D) decreasing7protein7synthesis7and7function
The7patient7has7a7prolonged7interruption7in7arterial7blood7flow7to7his7left7kidney,7causing7hypoxic
5. 7cell7injury7and7the7release7of7free7radicals.7Free7radicals7damage7cells7by:
A) destroying7phospholipids7in7the7cell7membrane.
B) altering7the7immune7response7of7the7cell.
C) disrupting7calcium7storage7in7the7cell.
, D) inactivation7of7enzymes7and7mitochondria.
6. Injured7cells7have7impaired7flow7of7substances7through7the7cell7membrane7as7a7result7of:
A) increased7fat7load.
B) altered7permeability.
C) altered7glucose7utilization.
D) increased7surface7receptors.
7. Reversible7adaptive7intracellular7responses7are7initiated7by:
A) stimulus7overload.
B) genetic7mutations.
C) chemical7messengers.
D) mitochondrial7DNA.
8. Injured7cells7become7very7swollen7as7a7result7of:
A) increased7cell7protein7synthesis.
B) altered7cell7volume7regulation.
C) passive7entry7of7potassium7into7the7cell.
D) bleb7formation7in7the7plasma7membrane.
A7diabetic7patient7has7impaired7sensation,7circulation,7and7oxygenation7of7his7feet.7He7steps7on7a7
piece7of7glass,7the7wound7does7not7heal,7and7the7area7tissue7becomes7necrotic.7The7necrotic7cell7
9. death7is7characterized7by:
A) rapid7apoptosis.
B) cellular7rupture.
C) shrinkage7and7collapse.
D) chronic7inflammation.
A799-year-
10. old7woman7has7experienced7the7decline7of7cell7function7associated7with7age.7A7group7of7theorie
s7of7cellular7aging7focus7on7programmed:
A) changes7with7genetic7influences.
B) elimination7of7cell7receptor7sites.
C) insufficient7telomerase7enzyme.
D) DNA7mutation7or7faulty7repair.
An789-year-
old7female7patient7has7experienced7significant7decreases7in7her7mobility7and7stamina7during7a73
-
11. week7hospital7stay7for7the7treatment7of7a7femoral7head7fracture.7Which7of7the7following7phenom
ena7most7likely7accounts7for7the7patients7decrease7in7muscle7function7that7underlies7her7reduced