COMLEX LEVEL 1 (ACTUAL 2025/2026) QUESTIONS WITH
VERIFIED 100% CORRECT ANSWERS GRADED A+
Atovaquone/Proguanil -----Answers---traditionally used to
treat babesia, it is also an alternative treatment for malaria if
first line agents fail
Chloroquine -----Answers---considered the drug of choice
for the treatment of the erythrocytic forms of all non-
falciparum species of plasmodium but there is a high rate of
*resistance* so other meds should be considered first
Mefloquine -----Answers---used for prophylaxis and
treatment for all susceptible malaria species
associated with sleep disturbances and not effective against
hypnozoites
quinidine -----Answers---class Ia antiarythmic and
antimalarial used IV for severe forms
*Vd=dose/Co*, A high Vd means a smaller percent remains in
the plasma (small Co) and thus is less likely to be bound to
plasma -----Answers---what does a drug with a high Volume
distribution mean?
,illness anxiety disorder (hypochondriasis) -----Answers---a
disorder in which a person interprets normal physical
sensations as symptoms of a disease
Generally SOMATIC SYMPTOMS ARE NOT PRESENT
Delusional disorder, somatic type -----Answers---delusions
that the person has some physical defect or general medical
condition for at least 1 month
DOES NOT FOCUS ON A CONCRETE ILLNESS
hypercapneic respiratory failure secondary to status
asthmaticus---> Will see an elevated serum hydrogen
concentration due to failure to blow off CO2 due to respiratory
muscle weakening -----Answers---patient with a history of
asthma presents with diaphragm flattening, a rib somatic
dysfunction and viserosomatic changes as well as increased
breathing rate, high BP, fast HR and decreased O2 sat on room
air.
What is this patient suffering from
Churg-Strauss Syndrome -----Answers---aka allergic
granulomatous angiitis,
,necrotizing vasculitis, variant of polyarteritis nodosa, involves
*pulmonary vasculature,* peripheral eosinophilia*, and asthma
p128
Characterized by increased ESR, neuropathy and associated
with p-ANCA
calcium gluconate -----Answers---Antidote for magnesium
sulfate
Loss of deep tendon reflexes -----Answers---Signs of
magnesium toxicity include respiratory paralysis, coma and
_______
*It is important to test for this once Mg Sulfate is administered
to patients with eclampsia*
croup -----Answers---most common infectious cause of
stridor in children younger than 3 years of age. Commonly
caused by parainfluenza virus and radiographs show the
classic steeple sign which is caused by laryngotracheal edema
LABA (salmeterol, formoterol) -----Answers---Patient
presents with difficulties controlling her daily asthma
symptoms of coughing and wheezing. Her SABA and low dose
corticosteroid are not working, what is the next medication
that should be tried in order to control her symptoms
, Asthmatic bronchospasm due to ASA sensitivity and treatment
is *zafrilukast* -----Answers---a child presents with poorly
controlled asthma, recent illness with fever and UR symptoms
as well as nasal polyps. She has also been given Aspirin today
to help with her myalgias
what is going on and what is the treatment?
imipenem -----Answers---beta-lactamase resistant cell wall
inhibitor
Cilastatin, inhibitor of renal dehydropeptidase I -----Answers-
--What is Imipenem always administered with?
WeCner's Granulomatosis aka granulomatosis w/polyangiitis
and c-ANCA -----Answers---mucosal ulcers, sinusitis and
rapidly progressive findings are classic findings of what
vasculitis? What is the associated finding?
Crohn's disease -----Answers---type of inflammatory bowel
disease that presents with watery diarrhea, arthritis, skin
rashes, uveitis and abdominal pain
*postitive for ASCA antibodies*
There is a compensatory increase in sodium reabsorption in
the distal tubule and chloride follows sodium so this causes
hyperchloremia -----Answers---acetazolamide prevents
VERIFIED 100% CORRECT ANSWERS GRADED A+
Atovaquone/Proguanil -----Answers---traditionally used to
treat babesia, it is also an alternative treatment for malaria if
first line agents fail
Chloroquine -----Answers---considered the drug of choice
for the treatment of the erythrocytic forms of all non-
falciparum species of plasmodium but there is a high rate of
*resistance* so other meds should be considered first
Mefloquine -----Answers---used for prophylaxis and
treatment for all susceptible malaria species
associated with sleep disturbances and not effective against
hypnozoites
quinidine -----Answers---class Ia antiarythmic and
antimalarial used IV for severe forms
*Vd=dose/Co*, A high Vd means a smaller percent remains in
the plasma (small Co) and thus is less likely to be bound to
plasma -----Answers---what does a drug with a high Volume
distribution mean?
,illness anxiety disorder (hypochondriasis) -----Answers---a
disorder in which a person interprets normal physical
sensations as symptoms of a disease
Generally SOMATIC SYMPTOMS ARE NOT PRESENT
Delusional disorder, somatic type -----Answers---delusions
that the person has some physical defect or general medical
condition for at least 1 month
DOES NOT FOCUS ON A CONCRETE ILLNESS
hypercapneic respiratory failure secondary to status
asthmaticus---> Will see an elevated serum hydrogen
concentration due to failure to blow off CO2 due to respiratory
muscle weakening -----Answers---patient with a history of
asthma presents with diaphragm flattening, a rib somatic
dysfunction and viserosomatic changes as well as increased
breathing rate, high BP, fast HR and decreased O2 sat on room
air.
What is this patient suffering from
Churg-Strauss Syndrome -----Answers---aka allergic
granulomatous angiitis,
,necrotizing vasculitis, variant of polyarteritis nodosa, involves
*pulmonary vasculature,* peripheral eosinophilia*, and asthma
p128
Characterized by increased ESR, neuropathy and associated
with p-ANCA
calcium gluconate -----Answers---Antidote for magnesium
sulfate
Loss of deep tendon reflexes -----Answers---Signs of
magnesium toxicity include respiratory paralysis, coma and
_______
*It is important to test for this once Mg Sulfate is administered
to patients with eclampsia*
croup -----Answers---most common infectious cause of
stridor in children younger than 3 years of age. Commonly
caused by parainfluenza virus and radiographs show the
classic steeple sign which is caused by laryngotracheal edema
LABA (salmeterol, formoterol) -----Answers---Patient
presents with difficulties controlling her daily asthma
symptoms of coughing and wheezing. Her SABA and low dose
corticosteroid are not working, what is the next medication
that should be tried in order to control her symptoms
, Asthmatic bronchospasm due to ASA sensitivity and treatment
is *zafrilukast* -----Answers---a child presents with poorly
controlled asthma, recent illness with fever and UR symptoms
as well as nasal polyps. She has also been given Aspirin today
to help with her myalgias
what is going on and what is the treatment?
imipenem -----Answers---beta-lactamase resistant cell wall
inhibitor
Cilastatin, inhibitor of renal dehydropeptidase I -----Answers-
--What is Imipenem always administered with?
WeCner's Granulomatosis aka granulomatosis w/polyangiitis
and c-ANCA -----Answers---mucosal ulcers, sinusitis and
rapidly progressive findings are classic findings of what
vasculitis? What is the associated finding?
Crohn's disease -----Answers---type of inflammatory bowel
disease that presents with watery diarrhea, arthritis, skin
rashes, uveitis and abdominal pain
*postitive for ASCA antibodies*
There is a compensatory increase in sodium reabsorption in
the distal tubule and chloride follows sodium so this causes
hyperchloremia -----Answers---acetazolamide prevents
