PCB 3023 Cell Bio Exam 3 questions and answers
graded A+ latest update
1. Chapter 3 &4
2. Be able to ex- *One end of the polypeptide chain has a free amino group, while the
plain the differ- opposite end has a free carboxyl group. (N-TERMINUs is teh single
ent kinds of amino end) and the (C-TERMINUS is the single cayboxyl end).
func- tions that
-The term POLYPEPTIDE is not synonymous with the term PROTEIN
pro- teins may
-A functional PROTEIN is not just a polypeptide chain but is one or more
per-
polypep-
form with one ex- tides precisely twisted, folded, and coiled into a molecule of a unique
shape.
ample of -Functions of proteins are completely dependent on the structure of the
each protein.
(A feature common to all protein function:)
-all proteins bind to other molecules
Ligand/substrate can be
-a small molecule (organic/inorganic)
-a macromolecule
-metal ion....
Two most important aspects of binding:
1. Binding strength/aflnity
2. Specificity
Functions of Proteins:
-Structural proteins, Eg. collagen
-Motor proteins, Eg. kinesin
-Transport proteins, Eg. potassium channel- Storage proteins, Eg. ferritin
-Hormonal proteins, Eg. insulin
-Immune proteins, Eg. immunoglobulin
1/
42
,PCB 3023 Cell Bio Exam 3 questions and answers
graded A+ latest update
Proteins are the
main building
blocks of cells from
which cells are
assembled and
they constitute
most of the cells
dry mass. execute
all myriad
functions.
ENZYMES promote
intracellular
chemical reactions
by providing
molecular sur-
faces.
2/
42
,PCB 3023 Cell Bio Exam 3 questions and answers
graded A+ latest update
The many FUNCTIONS of proteins are due to the many ditterent shapes
they adopt.
ENZYMES catalyze covalent bond breakage or formation
STRUCTURAL PROTEINS provide mechanical support to cells and tissues
TRANSPORT PROTEINS carry small molecules or ions
MOTOR PROTEINS generate movement within the
cell STORAGE PROTEIN store amino acids or ions
SIGNAL PROTEIN carry extracellular signals from cell to cell
RECEPTOR PROTEINS detect signals and transmit them to the cells
response ma- chinery
GENE REGULATORY PROTEINS bind to DNA to switch genes on and ott.
3. Be able to explain Ligand/substrate can be
the term Ligand -a small molecule (organic/inorganic)
for proteins -a macromolecule
-metal ion....
ALL PROTEINS BIND TO OTHER MOLECULES
4. What are theTwo most important aspects of binding:
two features 1. Binding strength/aflnity
that
2. Specificity
characterize
the Binding strength/aflnity
interaction of - tells us how strongly a protein binds its
a protein with ligand Kon
its ligand?
+ B AB
Kott
Assume that the rate of the association reaction can be written as Ron = kon
[A] [B] (first-order with respect to each reactant)and the rate of the
3/
42
, PCB 3023 Cell Bio Exam 3 questions and answers
graded A+ latest update
dissociation reaction can be
written as Rott = kott [AB]
(also first-order with
respect to the reactant)
4/
42
graded A+ latest update
1. Chapter 3 &4
2. Be able to ex- *One end of the polypeptide chain has a free amino group, while the
plain the differ- opposite end has a free carboxyl group. (N-TERMINUs is teh single
ent kinds of amino end) and the (C-TERMINUS is the single cayboxyl end).
func- tions that
-The term POLYPEPTIDE is not synonymous with the term PROTEIN
pro- teins may
-A functional PROTEIN is not just a polypeptide chain but is one or more
per-
polypep-
form with one ex- tides precisely twisted, folded, and coiled into a molecule of a unique
shape.
ample of -Functions of proteins are completely dependent on the structure of the
each protein.
(A feature common to all protein function:)
-all proteins bind to other molecules
Ligand/substrate can be
-a small molecule (organic/inorganic)
-a macromolecule
-metal ion....
Two most important aspects of binding:
1. Binding strength/aflnity
2. Specificity
Functions of Proteins:
-Structural proteins, Eg. collagen
-Motor proteins, Eg. kinesin
-Transport proteins, Eg. potassium channel- Storage proteins, Eg. ferritin
-Hormonal proteins, Eg. insulin
-Immune proteins, Eg. immunoglobulin
1/
42
,PCB 3023 Cell Bio Exam 3 questions and answers
graded A+ latest update
Proteins are the
main building
blocks of cells from
which cells are
assembled and
they constitute
most of the cells
dry mass. execute
all myriad
functions.
ENZYMES promote
intracellular
chemical reactions
by providing
molecular sur-
faces.
2/
42
,PCB 3023 Cell Bio Exam 3 questions and answers
graded A+ latest update
The many FUNCTIONS of proteins are due to the many ditterent shapes
they adopt.
ENZYMES catalyze covalent bond breakage or formation
STRUCTURAL PROTEINS provide mechanical support to cells and tissues
TRANSPORT PROTEINS carry small molecules or ions
MOTOR PROTEINS generate movement within the
cell STORAGE PROTEIN store amino acids or ions
SIGNAL PROTEIN carry extracellular signals from cell to cell
RECEPTOR PROTEINS detect signals and transmit them to the cells
response ma- chinery
GENE REGULATORY PROTEINS bind to DNA to switch genes on and ott.
3. Be able to explain Ligand/substrate can be
the term Ligand -a small molecule (organic/inorganic)
for proteins -a macromolecule
-metal ion....
ALL PROTEINS BIND TO OTHER MOLECULES
4. What are theTwo most important aspects of binding:
two features 1. Binding strength/aflnity
that
2. Specificity
characterize
the Binding strength/aflnity
interaction of - tells us how strongly a protein binds its
a protein with ligand Kon
its ligand?
+ B AB
Kott
Assume that the rate of the association reaction can be written as Ron = kon
[A] [B] (first-order with respect to each reactant)and the rate of the
3/
42
, PCB 3023 Cell Bio Exam 3 questions and answers
graded A+ latest update
dissociation reaction can be
written as Rott = kott [AB]
(also first-order with
respect to the reactant)
4/
42
