NBME high yield Exam Questions And
Answers |Latest 2025 | Guaranteed Pass
Pts with sickle cell are susceptible to infections by encapsulated bacteria such as... - Answer✔-
encapsulated bacteria: Strep pneumo, N. meningitidis, H. flu
- salmonella osteomyelitis
achondroplasia is inherited in a _____ pattern - Answer✔autosomal DOMINANT (50%
inheritance)
granuloma is formed & maintained by... - Answer✔- Th1 CD4+ T cells
- IL2: proliferation of T cells
- IFNg: recruitment of macrophages
- TNFa: leukocyte recruitment & maintenance
hip flexor + knee extender which functions to provide stability & control during ambulation,
DECELERATION (landing a jump) & rapid changes in movement (cutting in SOCCER) -
Answer✔rectus femoris
sartorius - Answer✔OBLIQUE orientation around anterior thigh
- hip flexion, external rotation, ABduction & knee flexion
- sitting in a CROSS LEGGED position
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LVOT & harsh systolic murmur in hypertrophic cardiomyopathy is caused by - Answer✔mitral
valve & interventricular septum
Gs subunit - Answer✔stimulatory G protein → adenyl cyclase → cAMP → PROTEIN KINASE A
- glucagon, TSH and PTH
nitrates - Answer✔stable angina tx
- VENODILATION → reduced venous return to heart
- decreased LVEDV & myocardial O2 demand
malrotation - Answer✔defect in normal rotation of midgut around SMA → volvulus
- BILIOUS vomiting
- hemodynamic instability
pyloric stenosis - Answer✔- abnormal growth of smooth muscle
- projectile NONbilious emesis
- palpable, olive shaped mass & visible peristalsis
- metabolic alkalosis & unconjugated hyperbilirubinemia
systemic mastocytosis - Answer✔mutation in KIT (CD 117)
- excessive histamine → flushing, pruritus, urticaria
- GASTRIC HYPERSECRETION
mitral regurgitation - Answer✔reflux of blood from LV into LA during systole
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- S3 gallop
- holosystolic murmur heard over cardiac APEX
- afterload decrease
- preload increase
- ejection fraction INCREASE bc SV increases
- SV = EDV-ESV
- EF = SV/EDV
mitral stenosis - Answer✔OPENING SNAP followed by rumbling diastolic murmur over cardiac
APEX
giant cell arteritis - Answer✔transmural granulomatous inflammation w/ fragmentation of
elastic fibers
- adults >50
- HEADACHES & jaw claudication
- ischemic optic neuropathy
- polymyalgia rheumatica
eosinophilic granulomatosis w/ polyangiitis (Churg Strauss) - Answer✔perivascular necrotizing
granulomas (epithelioid histiocytes) w/ eosinophilic infiltration
- p-ANCA (+)
- ASTHMA symptoms
- later: RPGN, skin symptoms
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