AGACNP BOARD REVIEW: Infectious
Disease & Fever
#1 MOST COMMON BACTERIAL STI - ANSCHLAMYDIA
#1 MOST COMMON VIRAL STI - ANSHPV - extended rx of cervical most cancers
ADVERSE EFFECTS OF ABX - ANS1. Linezolid
-Thrombocytopenia
2. Daptomycin
-Myopathy & inc. CPK
3. Imipenem
-Seizures
4.
ADVERSE EFFECTS OF ANTIVIRALS - ANS1.Valganciclovir/Ganciclovir
-Neutropenia & BM sup.
2. Ribavirin
-Anemia
three. Foscarnet
-Renal tox
ANAEROBES ABX - ANS1. GI (bacteroides):
-Flagyl * exceptional
-Carbapenems, Zosyn
2. Respiratory (anaerobic strep)
-Clindamycin *fine
three. Meds with NO anaerobic coverage:
-Amingoglcyosides
-Aztreonam
-Flouroquinolones
-Oxacillin/nafcillin
-All cephalasporins besides cefoxitin/cefotetan (2G ceph)
ANTIBIOTICS SAFE IN PREGNANCY - ANS1. Penicillins
2. Cephalasporins
three. Aztrenam (monobactam)
three. Erythmycin/Azithromycin (Macrolide)
ANTIFUNGAL AGENTS - ANS1. Fluconazole
-Candida, cryptococcus
2. Itraconazole
-same as fluconazole
, three. Voriconazole
-Covers all Candida
-Best initial agent for
Aspergillus
four. Posaconzole:
-mucomycosis
five. Echinocandins
-caspofungin, micafungin, anidulfungin
-*neutropenic (caspofungin) fever
-does NOT cover cryptococcus
6. Amphotericin
-Covers all Candida, cryptococcus & aspergillus
7
ANTIVIRAL AGENTS - ANS1.Acyclovir/Valacyclovir/Famciclovir:
-HSV, varicella
2. Valganciclovir/ganciclovir/foscarnet:
-CMV, HSV, varicella
3.Telaprevir/boceprevir/simprevir/sofosbuvir:
-Chronic hepaitits C
4. Oseltamivir/Zanamivir:
-Influenza A/B
5. Ribavirin:
-Hep C (in blend w/ interferon), RSV
6.Lamivudine/Interferon/Adefovir/Tenofovir/Entercavir/Telbivudine
-Chronic hep b
BETA-LACTAM ABX (4-instructions) - ANS1. Penicillin
2. Cephalosporins
3. Carbapenem
four. Monobactam (aztreonam)
C.DIFF: Classification & Treatment
-Moderate sickness - ANS-Pt. An be treat w/PO
-WBC>15
->50% boom in Cr
* Vancomycin a hundred twenty five mg PO QID x10-14 days
C.DIFF: Classification & Treatment
-Mild ailment - ANS-Pt. May be dealt with w/ PO
-WBC<15
-No increase in Cr
*Flagyl 500 mg PO TID x10-14 days
C.DIFF: Classification & Treatment
-Severe disease - ANS-Post operative
* Flagyl 500 mg IV Q6H + Vanco 500 mg PO Q6H
-Toxic Megacolon
Disease & Fever
#1 MOST COMMON BACTERIAL STI - ANSCHLAMYDIA
#1 MOST COMMON VIRAL STI - ANSHPV - extended rx of cervical most cancers
ADVERSE EFFECTS OF ABX - ANS1. Linezolid
-Thrombocytopenia
2. Daptomycin
-Myopathy & inc. CPK
3. Imipenem
-Seizures
4.
ADVERSE EFFECTS OF ANTIVIRALS - ANS1.Valganciclovir/Ganciclovir
-Neutropenia & BM sup.
2. Ribavirin
-Anemia
three. Foscarnet
-Renal tox
ANAEROBES ABX - ANS1. GI (bacteroides):
-Flagyl * exceptional
-Carbapenems, Zosyn
2. Respiratory (anaerobic strep)
-Clindamycin *fine
three. Meds with NO anaerobic coverage:
-Amingoglcyosides
-Aztreonam
-Flouroquinolones
-Oxacillin/nafcillin
-All cephalasporins besides cefoxitin/cefotetan (2G ceph)
ANTIBIOTICS SAFE IN PREGNANCY - ANS1. Penicillins
2. Cephalasporins
three. Aztrenam (monobactam)
three. Erythmycin/Azithromycin (Macrolide)
ANTIFUNGAL AGENTS - ANS1. Fluconazole
-Candida, cryptococcus
2. Itraconazole
-same as fluconazole
, three. Voriconazole
-Covers all Candida
-Best initial agent for
Aspergillus
four. Posaconzole:
-mucomycosis
five. Echinocandins
-caspofungin, micafungin, anidulfungin
-*neutropenic (caspofungin) fever
-does NOT cover cryptococcus
6. Amphotericin
-Covers all Candida, cryptococcus & aspergillus
7
ANTIVIRAL AGENTS - ANS1.Acyclovir/Valacyclovir/Famciclovir:
-HSV, varicella
2. Valganciclovir/ganciclovir/foscarnet:
-CMV, HSV, varicella
3.Telaprevir/boceprevir/simprevir/sofosbuvir:
-Chronic hepaitits C
4. Oseltamivir/Zanamivir:
-Influenza A/B
5. Ribavirin:
-Hep C (in blend w/ interferon), RSV
6.Lamivudine/Interferon/Adefovir/Tenofovir/Entercavir/Telbivudine
-Chronic hep b
BETA-LACTAM ABX (4-instructions) - ANS1. Penicillin
2. Cephalosporins
3. Carbapenem
four. Monobactam (aztreonam)
C.DIFF: Classification & Treatment
-Moderate sickness - ANS-Pt. An be treat w/PO
-WBC>15
->50% boom in Cr
* Vancomycin a hundred twenty five mg PO QID x10-14 days
C.DIFF: Classification & Treatment
-Mild ailment - ANS-Pt. May be dealt with w/ PO
-WBC<15
-No increase in Cr
*Flagyl 500 mg PO TID x10-14 days
C.DIFF: Classification & Treatment
-Severe disease - ANS-Post operative
* Flagyl 500 mg IV Q6H + Vanco 500 mg PO Q6H
-Toxic Megacolon
