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Bio 1A03 - Theme 4 Study Set Exam Questions Fully Solved.

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How is the process of prokaryotic cell division initiated? - Answer - DNA attaches to the inside of the plasma membrane by proteins - replication begins along an origin of replication region of the bacterial chromosome stem cells - Answer - undifferentiated cells - can reproduce indefinitely - are able to differentiate into specialized cells (under appropriate conditions) - adult stem cells are able to replace non-reproducing specialized cells What happens when muscle cells undergo injury? - Answer 1. quiescent satellite stem cells are activated (begin to divide to enable muscle regeneration) 2. activation leads to proliferation 3. leads to commitment to differentiation 4. leads to fusion of myoblasts 5. maturation into myofibre Interphase: S phase - Answer DNA synthesis - exact copies of every chromosome are created - newly synthesized molecules is associated with the histones and other chromosomal proteins that allow for tight compaction Interphase: G1 - Answer prep for DNA synthesis Interphase: G2 - Answer prep for mitosis Interphase: G0 - Answer pauses cell cycle - cells in this phase permanently are non-dividing cells prophase - Answer POLES - each chromosome appears as identical sister chromatids joined @ centromere - chromosomes CONDENSE - centrosomes radiate microtubules and migrate to opposite POLES

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Bio 1A03 - Theme 4 Study Set Exam
Questions Fully Solved.
How is the process of prokaryotic cell division initiated? - Answer - DNA attaches to the inside
of the plasma membrane by proteins

- replication begins along an origin of replication region of the bacterial chromosome



stem cells - Answer - undifferentiated cells

- can reproduce indefinitely

- are able to differentiate into specialized cells (under appropriate conditions)

- adult stem cells are able to replace non-reproducing specialized cells



What happens when muscle cells undergo injury? - Answer 1. quiescent satellite stem cells are
activated (begin to divide to enable muscle regeneration)

2. activation leads to proliferation

3. leads to commitment to differentiation

4. leads to fusion of myoblasts

5. maturation into myofibre



Interphase: S phase - Answer DNA synthesis

- exact copies of every chromosome are created

- newly synthesized molecules is associated with the histones and other chromosomal proteins
that allow for tight compaction



Interphase: G1 - Answer prep for DNA synthesis



Interphase: G2 - Answer prep for mitosis



Interphase: G0 - Answer pauses cell cycle

- cells in this phase permanently are non-dividing cells



prophase - Answer POLES

, pro-metaphase - Answer POLAR MICROTUBULES

- nuclear envelope starts to break down

- microtubules attach to chromosomes



metaphase - Answer MIDDLE

- chromosomes align at the middle

- kinetochore microtubules facilitate the alignment



anaphase - Answer APART

- sister chromatids separate and travel to opposite poles

- kinetochore microtubules begin to shorten

- polar microtubules help elongate the cell



telophase - Answer TWO NEW DAUGHTER CELLS

- nuclear envelope reforms

- chromosomes DEcondense

- spindle microtubules are broken down



cytokinesis - Answer CLEAVAGE

- contractile ring forms (made up of motor proteins)

- defined cleavage furrow forms



cyclin - Answer - increases and decreases with each subsequent cell division

- cyclin levels are highest in metaphase, decrease in telophase



cyclin-CDK - Answer - control the progression of the cell cycle

- phosphorylate target proteins involved in promoting cell division



G1/S cyclin-CDK complex - Answer - prepares cell for DNA replication

- increases the expression of histone proteins

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