CPJE CLINICAL QUESTIONS LATEST WITH QUESTIONS AND CORRECT
ANSWERS|A+GRADE
Rotigotine -(answer)Neupro patch: do not heat/ use during MRI
HLA b1502 -(answer)Test in Asians. Rash for carbamazepine (tegretol), phenytoin (Dilantin), fos
phenytoin (cerebyx)
Trastuzumab -(answer)Herceptin, her/Neu- ado-trastuzunab (kadcyla), lapatinib (tykerb) pertuzumab
(perjeta)
Hla- b 5701 -(answer)Don't give abacavir (ziagen), epzicom, trizivir
Not cross reactive a/ opioid allergy -(answer)Fentanyl, meperidine (Demerol), methadone (dolophine),
tramadol (ultram), tapentadol (nucynta)
Inducers -(answer)Ps porcs (phenytoin, smoking, phenobarbital, oxcarbazepine, rifampin,
carbamazepine, St. John's wort)
Inhibitors -(answer)Gpacman (grapefruit, pi's, azoles, cimetidine/cyclosporine, macrolides-
erytho/clarithro, amiodarone, non dihydro (dilt, verapamil)
If on amiodarone, decrease these drugs by 30-50% -(answer)Digoxin, warfarin, quinidine, procainanide,
statins
Statins with high risk of inhibition -(answer)Las (lova, atorva, simva)
,CPJE CLINICAL QUESTIONS LATEST WITH QUESTIONS AND CORRECT
ANSWERS|A+GRADE
Entecavir -(answer)Baraclude. Empty stomach for hep B that fail lamivudime and adefovir- se: peripheral
edema, nephrotoxic
Ribavirin -(answer)Copegus. W/ food bid for hep c, hepatotoxic, hemolytic anemia, preg x, psych
disorders, ci: renal disfxn
Glipizide -(answer)Glucotrol 30 min before break & dinner
Glimeprimide -(answer)Amaryl 1-2 mg qd w/ 1st meal
Glyburide -(answer)Diabeta, + metformin = glucovance, do not use w/ renal failure 2.5-5mg qd
Rosiglitazone -(answer)Avandia 4-8mg qd (tzd, exacerbate hf, liver damage, increases hdl, decreases
tg/total cholesterol) similar: pioglitazone (actos)
Repaglinide -(answer)Prandin 0.5-2mg TID 15-30 min before a meal, hypoglycemia- do not take with su's
Nateglinide -(answer)Starlix injection- 15-30 min before meals
Acarbose -(answer)Precose- w/ 1st bite of meal and water
Miglitol -(answer)Glyset w/ 1st bite of meal and water
Linagliptan -(answer)Tradjenta- 5 mg qd in morning with or without food, no renal adjustment
, CPJE CLINICAL QUESTIONS LATEST WITH QUESTIONS AND CORRECT
ANSWERS|A+GRADE
Saxagliptin -(answer)OnglyZa 2.5-5mg qd
Canaglifozin -(answer)Invokana 100mg qd before first meal of day for DM. Se: female genital mycotic
infxn, increased urination, hyperkalemia, can increase dig levels, ci: renal dx
Exenatide -(answer)Byetta 30-60 min before am & pm meals,medguide, pancreatitis, thyroid c-cell
carcinoma xr= bydureon
Liraglutide -(answer)Victoza QD thyroid c-cell carcinoma, more weight loss, less pancreatitis
Pramlintide -(answer)Symlin - injection, skip if no meals, weight loss
Insulin aspart -(answer)Novolog rapid
Insulin glulisine -(answer)Apidra rapid
Insulin lispro -(answer)Humalog rapid
Detemir -(answer)Levemir long acting
Insulin glargine -(answer)Lantus long acting
ANSWERS|A+GRADE
Rotigotine -(answer)Neupro patch: do not heat/ use during MRI
HLA b1502 -(answer)Test in Asians. Rash for carbamazepine (tegretol), phenytoin (Dilantin), fos
phenytoin (cerebyx)
Trastuzumab -(answer)Herceptin, her/Neu- ado-trastuzunab (kadcyla), lapatinib (tykerb) pertuzumab
(perjeta)
Hla- b 5701 -(answer)Don't give abacavir (ziagen), epzicom, trizivir
Not cross reactive a/ opioid allergy -(answer)Fentanyl, meperidine (Demerol), methadone (dolophine),
tramadol (ultram), tapentadol (nucynta)
Inducers -(answer)Ps porcs (phenytoin, smoking, phenobarbital, oxcarbazepine, rifampin,
carbamazepine, St. John's wort)
Inhibitors -(answer)Gpacman (grapefruit, pi's, azoles, cimetidine/cyclosporine, macrolides-
erytho/clarithro, amiodarone, non dihydro (dilt, verapamil)
If on amiodarone, decrease these drugs by 30-50% -(answer)Digoxin, warfarin, quinidine, procainanide,
statins
Statins with high risk of inhibition -(answer)Las (lova, atorva, simva)
,CPJE CLINICAL QUESTIONS LATEST WITH QUESTIONS AND CORRECT
ANSWERS|A+GRADE
Entecavir -(answer)Baraclude. Empty stomach for hep B that fail lamivudime and adefovir- se: peripheral
edema, nephrotoxic
Ribavirin -(answer)Copegus. W/ food bid for hep c, hepatotoxic, hemolytic anemia, preg x, psych
disorders, ci: renal disfxn
Glipizide -(answer)Glucotrol 30 min before break & dinner
Glimeprimide -(answer)Amaryl 1-2 mg qd w/ 1st meal
Glyburide -(answer)Diabeta, + metformin = glucovance, do not use w/ renal failure 2.5-5mg qd
Rosiglitazone -(answer)Avandia 4-8mg qd (tzd, exacerbate hf, liver damage, increases hdl, decreases
tg/total cholesterol) similar: pioglitazone (actos)
Repaglinide -(answer)Prandin 0.5-2mg TID 15-30 min before a meal, hypoglycemia- do not take with su's
Nateglinide -(answer)Starlix injection- 15-30 min before meals
Acarbose -(answer)Precose- w/ 1st bite of meal and water
Miglitol -(answer)Glyset w/ 1st bite of meal and water
Linagliptan -(answer)Tradjenta- 5 mg qd in morning with or without food, no renal adjustment
, CPJE CLINICAL QUESTIONS LATEST WITH QUESTIONS AND CORRECT
ANSWERS|A+GRADE
Saxagliptin -(answer)OnglyZa 2.5-5mg qd
Canaglifozin -(answer)Invokana 100mg qd before first meal of day for DM. Se: female genital mycotic
infxn, increased urination, hyperkalemia, can increase dig levels, ci: renal dx
Exenatide -(answer)Byetta 30-60 min before am & pm meals,medguide, pancreatitis, thyroid c-cell
carcinoma xr= bydureon
Liraglutide -(answer)Victoza QD thyroid c-cell carcinoma, more weight loss, less pancreatitis
Pramlintide -(answer)Symlin - injection, skip if no meals, weight loss
Insulin aspart -(answer)Novolog rapid
Insulin glulisine -(answer)Apidra rapid
Insulin lispro -(answer)Humalog rapid
Detemir -(answer)Levemir long acting
Insulin glargine -(answer)Lantus long acting
