AACN CMC QUESTIONS AND ANSWERS
LATEST 2025-2026 EXAM UPDATE
What is the role of the kidney is heart failure? - Answer-
Juxtaglomerular cells on the afferent arteriole release renin when renal
blood flow is reduced
What are the effects of ACE and ARBs? - Answer-preload and afterload
reduction due to venous and arterial vasodilation
What is the aldosterone blocker? What are the unwanted side effects? -
Answer-spironolactone -- indicated for HF and HTN
Potassium sparing diuretic
effect androgen and progesterone so it can cause sexual dysfunction,
gynecomastia, menstrual problems and breast pain
eplerenone -- most selective aldosterone blocker that does not have
unwanted side effects as above
What are the P2Y12 inhibitors? What are their indications? - Answer-
Clopidogrel (Plavix) -- Recent MI or Stroke. STEMI, UA, NSTEMI
managed medically or PCI or with CABG
, Prasugrel (Effient) -- STEMI, UA, or NSTEMI managed with PCI..
NOT for medical management
Ticagrelor (Brilinta) -- STEMI, UA, NSTEMI managed medically or
with PCI
GPII/IIIa inhibitors - Answer-Abciximab (Reopro)
Eptifibatide (Integrillin)
Tirofiban (Aggrastat)
ONLY IV
What is the contraindication of Prasugrel (Effient)? - Answer-History of
TIA or Stroke
How long is a platelets lifespan? - Answer-10 days
What drug decreases effect of Clopidogrel (Plavix) - Answer-PPIs -
inhibit enzyme that converts plavix
Direct Xa Inhibitors -- Anticoagulants - Answer-apixaban (Eliquis)
rivaroxaban (Xeralto)
edoxaban (Savaysa)
LATEST 2025-2026 EXAM UPDATE
What is the role of the kidney is heart failure? - Answer-
Juxtaglomerular cells on the afferent arteriole release renin when renal
blood flow is reduced
What are the effects of ACE and ARBs? - Answer-preload and afterload
reduction due to venous and arterial vasodilation
What is the aldosterone blocker? What are the unwanted side effects? -
Answer-spironolactone -- indicated for HF and HTN
Potassium sparing diuretic
effect androgen and progesterone so it can cause sexual dysfunction,
gynecomastia, menstrual problems and breast pain
eplerenone -- most selective aldosterone blocker that does not have
unwanted side effects as above
What are the P2Y12 inhibitors? What are their indications? - Answer-
Clopidogrel (Plavix) -- Recent MI or Stroke. STEMI, UA, NSTEMI
managed medically or PCI or with CABG
, Prasugrel (Effient) -- STEMI, UA, or NSTEMI managed with PCI..
NOT for medical management
Ticagrelor (Brilinta) -- STEMI, UA, NSTEMI managed medically or
with PCI
GPII/IIIa inhibitors - Answer-Abciximab (Reopro)
Eptifibatide (Integrillin)
Tirofiban (Aggrastat)
ONLY IV
What is the contraindication of Prasugrel (Effient)? - Answer-History of
TIA or Stroke
How long is a platelets lifespan? - Answer-10 days
What drug decreases effect of Clopidogrel (Plavix) - Answer-PPIs -
inhibit enzyme that converts plavix
Direct Xa Inhibitors -- Anticoagulants - Answer-apixaban (Eliquis)
rivaroxaban (Xeralto)
edoxaban (Savaysa)
