MPP Final Exam Correct Complete
Solutions GRADED A+.
MPP Final Exam Correct Complete
Solutions GRADED A+.
What is the name of the glucose transporters found on skeletal muscle and fat cells? (Pre Lab 1) -
ANSWER GLUT4
What is the name of the polymer which is the stored form of glucose? (Pre Lab 1) - ANSWER glycogen
The endocrine portion of the pancreas is made up of alpha cells and beta cells. What hormone is
produced and released by the beta cells of the pancreas? (Pre Lab 1) - ANSWER Insulin
What is the name of the peptide that is released from the pancreatic beta cells when insulin is
released?(Pre Lab 1) - ANSWER C-peptide
The endocrine portion of the pancreas is made up of alpha cells and beta cells. What hormone is
produced and released by the alpha cells of the pancreas? (Pre Lab 1) - ANSWER Glucagon
Match the following types of Diabetes mellitus to the pathological problem at the cellular level. (Pre Lab
1) - ANSWER Diabetes mellitus type 1- loss of pancreatic beta cells resulting in an inability to make and
secrete insulin
Diabetes mellitus type 2- target cells have less sensitive or resistant insulin receptors
Put the following steps involved in blood glucose regulation in order starting with ingesting a sugar-
containing meal. (Post Lab 1) - ANSWER Step 1: glucose is absorbed from the intestine to the blood
Step 2: Blood glucose levels increase
Step 3: Pancreatic alpha and beta cells sense increased blood glucose
Step 4: Insulin and C-peptides are released from pancreatic beta cells into the blood
Step 5: Insulin binds to insulin receptors on target cells: Liver, muscle, and fat cells
Step 6: glucose transporters allow glucose to move into muscle cells
,MPP Final Exam Correct Complete
Solutions GRADED A+.
Step 7: blood glucose levels return back to normal
Put the following steps involved in blood glucose regulation in order starting at least 6 hours after a
meal. (Post Lab 1) - ANSWER Step 1: Blood glucose levels decrease
Step 2: Pancreatic alpha and beta cells sense decreased blood glucose
Step 3: Pancreatic alpha cells release glucagon to the blood
Step 4: Glucagon signals liver and skeletal muscle to break down glycogen
Step 5: Liver cells release glucose to the blood
Step 6: Blood glucose levels return to normal
Select all the correct statements regarding glucose regulation: (Post Lab 1) - ANSWER -pancreatic alpha
and beta cells sense blood glucose levels
-Breakdown of liver glycogen is dependent on glucagon
-Uptake of glucose into resting skeletal muscles is dependent on insulin
NOT
-liver cells sense blood glucose levels
-Skeletal muscle senses blood glucose levels
Select the correct statement regarding diabetes mellitus type 1: (Post Lab 1) - ANSWER The beta cells
have been destroyed so insulin is not released in response to increased blood glucose levels
NOT
-The insulin receptors on skeletal muscle cells are not as responsive to insulin
-The alpha cells will secrete more glucagon
-The alpha cells have been destroyed so insulin is not released in response to increased blood glucose
levels
,MPP Final Exam Correct Complete
Solutions GRADED A+.
GLUT4 transports glucose from the blood into liver cells. (Pre Lab 2) - ANSWER False, GLUT4 transports
glucose from the blood to skeletal muscle and fat cells
Glucagon is secreted by pancreatic ____ cells when blood glucose levels ______ . (Pre Lab 2) - ANSWER
Alpha cells; decrease
During a glucose challenge, would a patient with type I diabetes secrete more or less insulin compared
to normal? (Pre Lab 2) - ANSWER Less
If a type I diabetic gave them self an insulin injection just after a meal, what will their blood levels of C-
peptide be? (Pre Lab 2) - ANSWER Low
The drug SU causes pancreatic beta cells to secrete more insulin into the blood than normal as a way to
combat insulin receptor insensitivity in type II diabetics. True or false: you would expect a patient's
blood C-peptide levels to be higher than normal if they are taking SU? (Pre Lab 2) - ANSWER True
Where are SGLT co-transporters found? (Pre Lab 2) - ANSWER Kidney tubule - SGLT2 co-transporters are
also found in the intestine to move glucose from the intestinal lumen into the epithelial cells.
What 2 molecules do the SGLTs transport? (Pre Lab 2) - ANSWER Glucose, Sodium
NOT
-insulin
-ATP
-glycogen
When blood glucose levels increase, more glucose molecules get filtered to the kidney? (Pre Lab 2) -
ANSWER True
When will glucose show up in the urine? (Pre Lab 2) - ANSWER only when blood glucose levels get very
high and saturate the SGLTs
, MPP Final Exam Correct Complete
Solutions GRADED A+.
Select the false statement about GLUT4 transporters. (Pre Lab 2) - ANSWER FALSE: They are found at the
membrane of skeletal muscle all the time
TRUE:
-In the absence of insulin, GLUT4s are found inside resting muscle cells
-GLUT4s are the glucose transports in fat cells
-Insulin binding to insulin receptors allows GLUT4s to transport glucose into muscle cells
-GLUT4s are important to take up excess glucose from the blood to fat and muscle cells
The SGLT2 transporters function via (Post Lab 2) - ANSWER Secondary active transport
Select the answer that is False regarding the regulation of blood glucose in a healthy person. - ANSWER
FALSE: the SGLT2s become saturated after a meal
TRUE:
-Glucagon signals the target cells to breakdown glycogen
-Glut4 transporters only allow glucose to move down its concentration gradient
-Glut 2 transporters only allow glucose to move down its concentration gradient
-All the glucose that gets filtered at the kidney glomerulus gets reabsorbed through the SGLT
transporters in the kidney tubule
-The urine threshold for glucose occurs when the SGLTs become saturated
Select all that are true when Glucose appears in the urine. - ANSWER TRUE:
-The SGLT2s have become saturated
-Not all the glucose that is being filtered is being reabsorbed
-Blood glucose levels are quite elevated
FALSE:
-Blood glucose regulation is normal
-The person is hypoglycemic
Solutions GRADED A+.
MPP Final Exam Correct Complete
Solutions GRADED A+.
What is the name of the glucose transporters found on skeletal muscle and fat cells? (Pre Lab 1) -
ANSWER GLUT4
What is the name of the polymer which is the stored form of glucose? (Pre Lab 1) - ANSWER glycogen
The endocrine portion of the pancreas is made up of alpha cells and beta cells. What hormone is
produced and released by the beta cells of the pancreas? (Pre Lab 1) - ANSWER Insulin
What is the name of the peptide that is released from the pancreatic beta cells when insulin is
released?(Pre Lab 1) - ANSWER C-peptide
The endocrine portion of the pancreas is made up of alpha cells and beta cells. What hormone is
produced and released by the alpha cells of the pancreas? (Pre Lab 1) - ANSWER Glucagon
Match the following types of Diabetes mellitus to the pathological problem at the cellular level. (Pre Lab
1) - ANSWER Diabetes mellitus type 1- loss of pancreatic beta cells resulting in an inability to make and
secrete insulin
Diabetes mellitus type 2- target cells have less sensitive or resistant insulin receptors
Put the following steps involved in blood glucose regulation in order starting with ingesting a sugar-
containing meal. (Post Lab 1) - ANSWER Step 1: glucose is absorbed from the intestine to the blood
Step 2: Blood glucose levels increase
Step 3: Pancreatic alpha and beta cells sense increased blood glucose
Step 4: Insulin and C-peptides are released from pancreatic beta cells into the blood
Step 5: Insulin binds to insulin receptors on target cells: Liver, muscle, and fat cells
Step 6: glucose transporters allow glucose to move into muscle cells
,MPP Final Exam Correct Complete
Solutions GRADED A+.
Step 7: blood glucose levels return back to normal
Put the following steps involved in blood glucose regulation in order starting at least 6 hours after a
meal. (Post Lab 1) - ANSWER Step 1: Blood glucose levels decrease
Step 2: Pancreatic alpha and beta cells sense decreased blood glucose
Step 3: Pancreatic alpha cells release glucagon to the blood
Step 4: Glucagon signals liver and skeletal muscle to break down glycogen
Step 5: Liver cells release glucose to the blood
Step 6: Blood glucose levels return to normal
Select all the correct statements regarding glucose regulation: (Post Lab 1) - ANSWER -pancreatic alpha
and beta cells sense blood glucose levels
-Breakdown of liver glycogen is dependent on glucagon
-Uptake of glucose into resting skeletal muscles is dependent on insulin
NOT
-liver cells sense blood glucose levels
-Skeletal muscle senses blood glucose levels
Select the correct statement regarding diabetes mellitus type 1: (Post Lab 1) - ANSWER The beta cells
have been destroyed so insulin is not released in response to increased blood glucose levels
NOT
-The insulin receptors on skeletal muscle cells are not as responsive to insulin
-The alpha cells will secrete more glucagon
-The alpha cells have been destroyed so insulin is not released in response to increased blood glucose
levels
,MPP Final Exam Correct Complete
Solutions GRADED A+.
GLUT4 transports glucose from the blood into liver cells. (Pre Lab 2) - ANSWER False, GLUT4 transports
glucose from the blood to skeletal muscle and fat cells
Glucagon is secreted by pancreatic ____ cells when blood glucose levels ______ . (Pre Lab 2) - ANSWER
Alpha cells; decrease
During a glucose challenge, would a patient with type I diabetes secrete more or less insulin compared
to normal? (Pre Lab 2) - ANSWER Less
If a type I diabetic gave them self an insulin injection just after a meal, what will their blood levels of C-
peptide be? (Pre Lab 2) - ANSWER Low
The drug SU causes pancreatic beta cells to secrete more insulin into the blood than normal as a way to
combat insulin receptor insensitivity in type II diabetics. True or false: you would expect a patient's
blood C-peptide levels to be higher than normal if they are taking SU? (Pre Lab 2) - ANSWER True
Where are SGLT co-transporters found? (Pre Lab 2) - ANSWER Kidney tubule - SGLT2 co-transporters are
also found in the intestine to move glucose from the intestinal lumen into the epithelial cells.
What 2 molecules do the SGLTs transport? (Pre Lab 2) - ANSWER Glucose, Sodium
NOT
-insulin
-ATP
-glycogen
When blood glucose levels increase, more glucose molecules get filtered to the kidney? (Pre Lab 2) -
ANSWER True
When will glucose show up in the urine? (Pre Lab 2) - ANSWER only when blood glucose levels get very
high and saturate the SGLTs
, MPP Final Exam Correct Complete
Solutions GRADED A+.
Select the false statement about GLUT4 transporters. (Pre Lab 2) - ANSWER FALSE: They are found at the
membrane of skeletal muscle all the time
TRUE:
-In the absence of insulin, GLUT4s are found inside resting muscle cells
-GLUT4s are the glucose transports in fat cells
-Insulin binding to insulin receptors allows GLUT4s to transport glucose into muscle cells
-GLUT4s are important to take up excess glucose from the blood to fat and muscle cells
The SGLT2 transporters function via (Post Lab 2) - ANSWER Secondary active transport
Select the answer that is False regarding the regulation of blood glucose in a healthy person. - ANSWER
FALSE: the SGLT2s become saturated after a meal
TRUE:
-Glucagon signals the target cells to breakdown glycogen
-Glut4 transporters only allow glucose to move down its concentration gradient
-Glut 2 transporters only allow glucose to move down its concentration gradient
-All the glucose that gets filtered at the kidney glomerulus gets reabsorbed through the SGLT
transporters in the kidney tubule
-The urine threshold for glucose occurs when the SGLTs become saturated
Select all that are true when Glucose appears in the urine. - ANSWER TRUE:
-The SGLT2s have become saturated
-Not all the glucose that is being filtered is being reabsorbed
-Blood glucose levels are quite elevated
FALSE:
-Blood glucose regulation is normal
-The person is hypoglycemic
