1
NBME 31
NBME 31 TEST 3 (2025/2026 UPDATE)
QUESTIONS & ANSWERS |GRADE A|100%
CORRECT (VERIFIED SOLUTION)
1. What are the other types of glycogen storage disease?: Vice
Presidents Can Take Money
Von Gierke [G-6-Phosphotase] - impaired gluconeogenesis and
glycolysis | Increased Glycogen in liver | increase uric acid (gout) |
increase lactate | inc. triglycerides
Pompe [a-1,4 glucoside, acid maltase, lysosomal] - increase glycogen
accumulate in lysosome |
hypotonia, severe cardiomyopathy, enlarged tongue, impaired exercise
[Pompe trashes the pump]
ABCD --
Cori [Debranching, a-1,6 glucosidase]-
NBME 31
, 2
NBME 31
~ VG, normal lactate, limit-dextrin accumulate in cytosol | Ketototic
hypoglycemia *gluconeogenesis intact*
Anderson [Branching Enzyme] - impaired glycogen synthesis | FTT
and hepatosplenomegaly
McArdle [myophosphorylase | glycogen phosphorylase] - Muscle|
impaired glycogenolysis | normal lactate levels during excercise,
increased ammonia
2. fever, chills, sob, exposure to hay on farm, resolved:
Hypersensitivity pneumonitis (following an exposure) - Farmer's Lung
or Bird's Fancier
CXR may be normal or show interstitial infiltrates
3. asthma, eosinophilia, bronchietasis, low grade fever,
hemoptysis: Allergic Bronchopulmonary Asperillgus
Transient infiltrates on imaging
4. cotton mill, textile workers, sob,: Byssinosis (Injury pathology)
Desquamative Interstitial pneumonia and diffuse alveolar damage
NBME 31
, 3
NBME 31
Histology:
- alveolar septa are thickened by infiltration of macrophages
5. progressive onset of dyspnea, increased sputum production,
alveolar space filled with proteinaceous material due to defect
surfactant deficiency and macrophage clearance: Pulmonary
Alveolar Proteinouses
6. Different levels of medical interventions: Clinical: in the clinic,
at the individual level
Community: targets at the community level
Primary: Prevention
Secondary: Screening: identify disease early in the course
Tertiary: Treatment, to slow or ameloriate the progression of disease
7. low back pain that radiates to thigh, muscle strength 5/5,
sensation to pink prick decreased over later aspect of left foot,
what else could be not functioning?: S1- Lateral foot (sensory),
gastroneumius, achilles tendon (muscle) Radiculopathy follows
dermatome and myotome distribution
NBME 31
, 4
NBME 31
Follows LMNs + sensory issues
LMNS:
- hyporeflexia
- fasiculations
- atrophy (only chronic)
8. Abdominal pain, diaphoresis, weakness, wheezing, salivating,
spilled chemical on self, tx with Atropine and pralidoxemine, dx?:
AChesterase poisoning
Drugs:
Parathion, fenthion, methionine
Carbaryl [TRANSIET]
9. Nicotinic vs Muscuranic Receptors:
10. nonproductive cough, joint pain w/ prednisone, small painless
nodules on extensor surface of both arms, ulnar deviation, an
swan neck deformities, bilateral adhesion, diffuse fibronodular
NBME 31
NBME 31
NBME 31 TEST 3 (2025/2026 UPDATE)
QUESTIONS & ANSWERS |GRADE A|100%
CORRECT (VERIFIED SOLUTION)
1. What are the other types of glycogen storage disease?: Vice
Presidents Can Take Money
Von Gierke [G-6-Phosphotase] - impaired gluconeogenesis and
glycolysis | Increased Glycogen in liver | increase uric acid (gout) |
increase lactate | inc. triglycerides
Pompe [a-1,4 glucoside, acid maltase, lysosomal] - increase glycogen
accumulate in lysosome |
hypotonia, severe cardiomyopathy, enlarged tongue, impaired exercise
[Pompe trashes the pump]
ABCD --
Cori [Debranching, a-1,6 glucosidase]-
NBME 31
, 2
NBME 31
~ VG, normal lactate, limit-dextrin accumulate in cytosol | Ketototic
hypoglycemia *gluconeogenesis intact*
Anderson [Branching Enzyme] - impaired glycogen synthesis | FTT
and hepatosplenomegaly
McArdle [myophosphorylase | glycogen phosphorylase] - Muscle|
impaired glycogenolysis | normal lactate levels during excercise,
increased ammonia
2. fever, chills, sob, exposure to hay on farm, resolved:
Hypersensitivity pneumonitis (following an exposure) - Farmer's Lung
or Bird's Fancier
CXR may be normal or show interstitial infiltrates
3. asthma, eosinophilia, bronchietasis, low grade fever,
hemoptysis: Allergic Bronchopulmonary Asperillgus
Transient infiltrates on imaging
4. cotton mill, textile workers, sob,: Byssinosis (Injury pathology)
Desquamative Interstitial pneumonia and diffuse alveolar damage
NBME 31
, 3
NBME 31
Histology:
- alveolar septa are thickened by infiltration of macrophages
5. progressive onset of dyspnea, increased sputum production,
alveolar space filled with proteinaceous material due to defect
surfactant deficiency and macrophage clearance: Pulmonary
Alveolar Proteinouses
6. Different levels of medical interventions: Clinical: in the clinic,
at the individual level
Community: targets at the community level
Primary: Prevention
Secondary: Screening: identify disease early in the course
Tertiary: Treatment, to slow or ameloriate the progression of disease
7. low back pain that radiates to thigh, muscle strength 5/5,
sensation to pink prick decreased over later aspect of left foot,
what else could be not functioning?: S1- Lateral foot (sensory),
gastroneumius, achilles tendon (muscle) Radiculopathy follows
dermatome and myotome distribution
NBME 31
, 4
NBME 31
Follows LMNs + sensory issues
LMNS:
- hyporeflexia
- fasiculations
- atrophy (only chronic)
8. Abdominal pain, diaphoresis, weakness, wheezing, salivating,
spilled chemical on self, tx with Atropine and pralidoxemine, dx?:
AChesterase poisoning
Drugs:
Parathion, fenthion, methionine
Carbaryl [TRANSIET]
9. Nicotinic vs Muscuranic Receptors:
10. nonproductive cough, joint pain w/ prednisone, small painless
nodules on extensor surface of both arms, ulnar deviation, an
swan neck deformities, bilateral adhesion, diffuse fibronodular
NBME 31
