Test Bank for Clayton’s Basic Pharmacology for Nurses 19th Edition by Michelle J. Willihnganz || Samuel L. Gurevitz || Bruce Clayton Complete Update 2025

Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
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Chapter 01: Drug Definitions, Standards, and Information Sources
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Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
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MULTIPLE CHOICE e




1. Which name identifies a drug listed by the US Food and
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Drug Administration (FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C e


The official name is the name under which a drug is listed
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by the FDA. The brand name, or trademark, is the name
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given to a drug by its manufacturer. The nonproprietary, or
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generic, name is provided by the United States Adopted
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Names Council.
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DIF: Cognitive Level: Knowledge REF: p. 9 e e e e


OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care
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Environment TOP: Nursing Process Step: Assessment
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Patient Education
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2. Which source contains information specific to nutritional supplements?
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a. USP Dictionary of USAN & International Drug Names
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b. Natural Medicines Comprehensive Database e e e


c. United States Pharmacopoeia/National Formulary (USP NF)
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d. Drug Interaction Facts e e




ANS: C e


United States Pharmacopoeia/National Formulary contains information specific to nutritional
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supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug
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names, pronunciation guide, and possible future FDA approved drugs; it does not include
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nutritional supplements. Natural Medicines Comprehensive Database contains
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evidence-based information on herbal medicines and herbal combination products; it does not
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include information specific to nutritional supplements. Drug Interaction Facts contains
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comprehensive information on drug interaction facts; it does not include nutritional
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supplements.
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DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3 e e e e e


NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
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3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
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a. Drug Facts and Comparisons e e e




Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
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,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
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b. Drug Interaction Facts e e


c. Handbook on Injectable Drugs e e e


d. Martindale—The Complete Drug Reference e e e




ANS: A e


Drug Facts and Comparisons contains drug monographs that describe all drugs in a
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therapeutic class. Monographs are formatted as tables to allow comparison of similar
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products, brand names, manufacturers, cost indices, and available dosage forms
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Online version is available.
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DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 e e e e e e


OBJ: 3 e NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
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4. Which drug reference contains monographs about virtually every single-entity drug available
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in the United States and describes therapeutic uses of drugs, including approved and
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unapproved uses?
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a. Martindale: The Complete Drug Reference e e e e


b. AHFS Drug Information e e


c. Drug Reference e


d. Drug Facts and Comparisons e e e




ANS: B e


AHFS Drug Information contains monographs about virtually every single-entity drug
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available in the United States and describes therapeutic uses of drugs, including approved and
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unapproved uses.
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DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 e e e e e e


OBJ: 3 e NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Planning
e CON: Safety | Patient Education | Clinical Judgment
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5. Which online drug reference makes available to healthcare providers and the public a
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estandard, comprehensive, up-to-date look up and downloadable resource about medicines?
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a. American Drug Index e e


b. American Hospital Formulary e e


c. DailyMed
d. Drug Reference e




ANS: C e


DailyMed makes available to healthcare providers and the public a standard, comprehensive,
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up-to-date look up and downloadable resource about medicines. The American Drug Index is
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not appropriate for patient use. The American Hospital Formulary is not appropriate for
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patient use. The drug reference is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 e e e e e e e OBJ: 3 e


NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Implementation
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CON: Safety | Patient Education | Clinical Judgment
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6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
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a. Federal Food, Drug, and Cosmetic Act (1938) e e e e e e


b. Durham Humphrey Amendment (1952) e e e




Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
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,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
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c. Controlled Substances Act (1970) e e e


d. Kefauver Harris Drug Amendment (1962) e e e e




ANS: A e


The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
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safety of all drugs before marketing. Later amendments and acts helped tighten FDA control
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and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that
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cannot be used safely without medical supervision and restricts their sale to prescription by a
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licensed practitioner. The Controlled Substances Act addresses only controlled substances and
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their categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater
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drug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their
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products before marketing them.
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DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 e e e e e e


OBJ: 5 eNAT: NCLEX Client Needs Category: Physiological Integrity e e e e e e


TOP: Nursing Process Step: Assessment
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CON: Safety | Patient Education | Evidence | Health Care Law
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7. Which classification does meperidine (Demerol) fall under?
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a. I
b. II
c. III
d. IV
ANS: B e


Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to
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severe psychological and physical dependence. Schedule I drugs have high potential for abuse
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and no recognized medical use. Schedule III drugs have some potential for abuse. Use may
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lead to low to moderate physical dependence or high psychological dependence. Schedule IV
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drugs have low potential for abuse. Use may lead to limited physical or psychological
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dependence.
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DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2 e e e e e


NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
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TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
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8. Which action would the FDA take to expedite drug development and approval for an outbreak
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of smallpox?
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a. List smallpox as a health orphan disease.
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b. Omit the preclinical research phase. e e e e


c. Extend the clinical research phase. e e e e


d. Fast track the investigational drug.e e e e




ANS: D e


Once the Investigational New Drug Application has been approved, the drug can receive
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highest priority within the agency, which is called fast tracking. A smallpox outbreak would
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become a priority concern in the world. Orphan diseases are not researched in a priority
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manner. Preclinical research is not omitted. Extending any phase of the research would mean
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a longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical and
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clinical research phase have been completed in a safe manner.
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DIF: Cognitive Level: Knowledge e e REF: p. 7 e e e OBJ: 5 e




Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
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NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
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TOP: Nursing Process Step: Assessment
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CON: Health Care Law | Health Care Policy | Infection | Care Coordination
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9. Which statement is true about over-the-counter (OTC) drugs?
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a. They are not listed in the USP NF. e e e e e e e


b. A prescription from a healthcare provider is needed.
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c. They are sold without a prescription.e e e e e


d. They are known only by their brand names.
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ANS: C e


OTC medications do not require a prescription. A variety of names, both generic and trade,
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can be used for individual drugs sold OTC. OTC drugs are listed in the USP NF. Prescription
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drugs require an order by a health professional who is licensed to prescribe, such as a
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physician, nurse practitioner, physician assistant, or dentist.
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DIF: Cognitive Level: Comprehension REF: p. 2 OBJ: 2 e e e e e


NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Planning
e CON: Patient Education e e e e e




10. Which is the most authoritative reference for medications that are injected?
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a. Martindale: The Complete e e


b. Handbook on Injectable Drugs e e e


c. DailyMed
d. Handbook of Nonprescription Drugs e e e




ANS: B e


The Handbook on Injectable Drugs is the most comprehensive reference available on the
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topic of compatibility of injectable drugs. It is a collection of monographs for more than 300
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injectable drugs that are listed alphabetically by generic name.
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DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3 e e e e e


NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety
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11. Which statement is true about Lomotil?
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a. Abuse potential for this drug is low. e e e e e e


b. Psychological dependency is likely. e e e


c. There is a high potential for abuse. e e e e e e


d. This drug is not a controlled substance.
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ANS: A e


Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological
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dependence liability compared with drugs in Schedule IV. Because abuse potential is low with
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a Schedule V drug, a prescription may not be required. Psychological dependency is not likely
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with a Schedule V drug. Schedule V drugs are classified as controlled substances.
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DIF: Cognitive Level: Knowledge REF: p. 5 Box 1.1 OBJ: 2 e e e e e e e


NAT: NCLEX Client Needs Category: Physiological Integrity
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TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety | Patient Education
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