MaryvilleNURS
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615 Pharm 1 exam
h h h h
, Nurs 615 Pharm Exam 1 - Maryville
h h h h h h
Study online at https://quizlet.com/_56ytfw
h h h
1. Howdoeshypoalbu-
h h Low albumin = more free drug (bc the drug can't bind to
h h h h h h h h h h h
minemia affect the
h h h albumin aka protein) = increased adverse effects
h h h h h h h
process of prescrib-
h h h
ing?
h
is considered a contraindication to administer that
h h h h h h
2. What is a Black Box h h h h drug.
h
Warning:
h
Half-life specifically means the amount of time it h h h h h h h
3. Whatis the drugs h h h takes for an administered drug to be halfway
h h h h h h h h
half-life?
h cleared from the system.
h h h h
4. Peak of action: h h thetimebetween drugadministrationand maxi-
h h h h h h
mum concentration of drug in the blood stream. Best
h h h h h h h h
therapeutic effect.
h h
5. Duration ofaction: h h thetime between onset of action and metabolism of
h h h h h h h h
drug below the minimum needed for an effect. The
h h h h h h h h
length of time you have the drug in your system.
h h h h h h h h h h
6. Accordingtothe WHO h h h The first step is to define the patient's problem
h h h h h h h h
what is the first
h h h h
stepintheprescribing
h h h
process?
h
7. The second step is to
h h h h specifythetherapeutic objective h h h
8. The third step is to
h h h h choose which drug ortreatment is needed. h h h h h h
9. Step 4 of the WHO ap-
h h h h h Start the treatment Educate h h h
proach:
h
10. Step 5 of the WHO ap-
h h h h h the patient Monitorthe
h h h h
proach:
h
11. Step 6 of the WHO ap-
h h h h h treatment
h
proach:
h
12. Phase 1 ofdrug devel- h h h h The drug is tested on healthy volunteers
h h h h h h
opment:
h
h h
, Nurs 615 Pharm Exam 1 - Maryville
h h h h h h
Study online at https://quizlet.com/_56ytfw
h h h
13. Phase 2 of drug devel- h h h h trials with people who have the disease for which the
h h h h h h h h h
opment:
h drug is thought to be effective
h h h h h h
14. Phase 3 of drug devel- h h h h Large numbers of patients in medical research cen-
h h h h h h h
opment:
h ters receive the drug in phase 3. This larger sam- pling
h h h h h h h h h h h
provides information about infrequent or rare adverse
h h h h h h h
effects. The FFA will approve a new drug application if
h h h h h h h h h h
phase 3 studies are satisfactory.
h h h h h
15. Phase 4 of drug devel- h h h h This phase is voluntary and involves postmarket
h h h h h h
opment:
h surveillance of the drug's therapeutic effects at the
h h h h h h h h
completion of phase 3. The pharmaceutical compa-
h h h h h h h
ny receives reports from doctors and other health care
h h h h h h h h h
professionals about the therapeutic results and
h h h h h h
adverse effects of the drug. Some medications, for
h h h h h h h h
example, have been found to be toxic and have been
h h h h h h h h h h
removed from the market after their initial release.
h h h h h h h h
much of the drug is lost in the absorption process. The
h h h h h h h h h h
16. Explain firstpassme- h h h liver metabolizes many drugs, thus reduces the
h h h h h h h
tabolism
h bioavailabilty of the drug.
h h h h
The fastest route of absorption is inhalation, and not
h h h h h h h h
17. What is the fastedh h h as mistakenly considered the IV administration.
h h h h h h
routeofabsorption:
h h h
The GI tract is lined with epithelial cells; drugs must
h h h h h h h h h
18. Why does the GI tract
h h h h permeate through these cells in order to be absorbed
h h h h h h h h h
takelongertoabsorb?
h h h h into the circulatory system.
h h h h
the cell membrane. Cell membranes are essen- tially
h h h h h h h
19. What is One particu-
h h h lipid bilayers which form a semipermeable
h h h h h h
larcellularbarrierthat
h h h h membrane. Pure lipid bilayers are generally perme-
h h h h h h h
may prevent absorp-
h h h able only to small and uncharged solutes, hence
h h h h h h h h
tion of a given drug?
h h h h h whether or not a molecule is ionized will affect its
h h h h h h h h h h
absorption, since ionic molecules are charged.
h h h h h h
20. What is solubility?
h h Solubilityfavorschargedspecies,permeabilityfa- h h h h h
vorsneutralspecies.Some molecules havespecial
h h h h h h
h h
h
615 Pharm 1 exam
h h h h
, Nurs 615 Pharm Exam 1 - Maryville
h h h h h h
Study online at https://quizlet.com/_56ytfw
h h h
1. Howdoeshypoalbu-
h h Low albumin = more free drug (bc the drug can't bind to
h h h h h h h h h h h
minemia affect the
h h h albumin aka protein) = increased adverse effects
h h h h h h h
process of prescrib-
h h h
ing?
h
is considered a contraindication to administer that
h h h h h h
2. What is a Black Box h h h h drug.
h
Warning:
h
Half-life specifically means the amount of time it h h h h h h h
3. Whatis the drugs h h h takes for an administered drug to be halfway
h h h h h h h h
half-life?
h cleared from the system.
h h h h
4. Peak of action: h h thetimebetween drugadministrationand maxi-
h h h h h h
mum concentration of drug in the blood stream. Best
h h h h h h h h
therapeutic effect.
h h
5. Duration ofaction: h h thetime between onset of action and metabolism of
h h h h h h h h
drug below the minimum needed for an effect. The
h h h h h h h h
length of time you have the drug in your system.
h h h h h h h h h h
6. Accordingtothe WHO h h h The first step is to define the patient's problem
h h h h h h h h
what is the first
h h h h
stepintheprescribing
h h h
process?
h
7. The second step is to
h h h h specifythetherapeutic objective h h h
8. The third step is to
h h h h choose which drug ortreatment is needed. h h h h h h
9. Step 4 of the WHO ap-
h h h h h Start the treatment Educate h h h
proach:
h
10. Step 5 of the WHO ap-
h h h h h the patient Monitorthe
h h h h
proach:
h
11. Step 6 of the WHO ap-
h h h h h treatment
h
proach:
h
12. Phase 1 ofdrug devel- h h h h The drug is tested on healthy volunteers
h h h h h h
opment:
h
h h
, Nurs 615 Pharm Exam 1 - Maryville
h h h h h h
Study online at https://quizlet.com/_56ytfw
h h h
13. Phase 2 of drug devel- h h h h trials with people who have the disease for which the
h h h h h h h h h
opment:
h drug is thought to be effective
h h h h h h
14. Phase 3 of drug devel- h h h h Large numbers of patients in medical research cen-
h h h h h h h
opment:
h ters receive the drug in phase 3. This larger sam- pling
h h h h h h h h h h h
provides information about infrequent or rare adverse
h h h h h h h
effects. The FFA will approve a new drug application if
h h h h h h h h h h
phase 3 studies are satisfactory.
h h h h h
15. Phase 4 of drug devel- h h h h This phase is voluntary and involves postmarket
h h h h h h
opment:
h surveillance of the drug's therapeutic effects at the
h h h h h h h h
completion of phase 3. The pharmaceutical compa-
h h h h h h h
ny receives reports from doctors and other health care
h h h h h h h h h
professionals about the therapeutic results and
h h h h h h
adverse effects of the drug. Some medications, for
h h h h h h h h
example, have been found to be toxic and have been
h h h h h h h h h h
removed from the market after their initial release.
h h h h h h h h
much of the drug is lost in the absorption process. The
h h h h h h h h h h
16. Explain firstpassme- h h h liver metabolizes many drugs, thus reduces the
h h h h h h h
tabolism
h bioavailabilty of the drug.
h h h h
The fastest route of absorption is inhalation, and not
h h h h h h h h
17. What is the fastedh h h as mistakenly considered the IV administration.
h h h h h h
routeofabsorption:
h h h
The GI tract is lined with epithelial cells; drugs must
h h h h h h h h h
18. Why does the GI tract
h h h h permeate through these cells in order to be absorbed
h h h h h h h h h
takelongertoabsorb?
h h h h into the circulatory system.
h h h h
the cell membrane. Cell membranes are essen- tially
h h h h h h h
19. What is One particu-
h h h lipid bilayers which form a semipermeable
h h h h h h
larcellularbarrierthat
h h h h membrane. Pure lipid bilayers are generally perme-
h h h h h h h
may prevent absorp-
h h h able only to small and uncharged solutes, hence
h h h h h h h h
tion of a given drug?
h h h h h whether or not a molecule is ionized will affect its
h h h h h h h h h h
absorption, since ionic molecules are charged.
h h h h h h
20. What is solubility?
h h Solubilityfavorschargedspecies,permeabilityfa- h h h h h
vorsneutralspecies.Some molecules havespecial
h h h h h h
h h
