Walden NURS 6630 Psychopharmacology Study Guide Questions with Detailed Verified Answers (100% Correct Answers) /Already Graded A+

classic synaptic neurotransmission Ans: stimulation of a presynaptic neuron (e.g., by neurotransmitters, light, drugs, hormones, nerve impulses) causes electrical impulses to be sent to its axon terminal. These electrical impulses are then converted into chemical messengers and released to stimulate the receptors of a postsynaptic neuron. The synaptic cleft Ans: is the gap between the presynaptic neuron and the postsynaptic neuron; it contains proteins and scaffolding and molecular forms of "synaptic glue" to reinforce the connection between the neurons. Receptors are present on both sides of this cleft and are key elements of chemical neurotransmission. the soma Ans: is the command center of the nerve and contains the nucleus of the cell axon Ans: Neurons send information via an ____ that forms presynaptic terminals as the ____ passes by (en passant) or as the ____ ends axodendritic Ans: synaptic connections between the axon and dendrites of two neurons axosomatic Ans: synaptic connections between the axon and the soma axoaxonic Ans: synaptic connections between axons of the two neurons 2 Exampromax - Stuvia US2025/2026 Approved By: Exampromax - Stuvia US The chemical basis of neurotransmission Ans: is how chemical signals are coded, decoded, transduced, and sent along the way. The anatomical basis of neurotransmission Ans: is neurons and the connections between them, called synapses, sometimes also called the anatomically addressed nervous system, a complex of "hard-wired" synaptic connections between neurons, not unlike millions of telephone wires within thousands upon thousands of cables The cytochrome P450 (CYP) enzyme system Ans: mediates how the body metabolizes many drugs, including antipsychotics. The CYP enzyme Ans: in the gut wall or liver converts the drug into a biotransformed product in the bloodstream. After passing through the gut wall and liver, the drug will exist partly as unchanged drug and partly as biotransformed drug. agonist Ans: produces a conformational change in the G-protein-linked receptor that turns on the synthesis of second messenger to the greatest extent possible full agonist Ans: is generally represented by the naturally occurring neurotransmitter itself, although some drugs can also act in as full a manner as the natural neurotransmitter Constitutive activity Ans: in the absence of agonist, the receptor's conformation is such that it leads to a low level of activity