Summary PHYSIO 1 Lecture EXAM IV Study Guide Part 4

LECTURE EXAM IV STUDY GUIDE Part 4
Review how hormones regulate the male reproductive system.
o Endocrine Regulation
 FSH stimulates Sertoli cells of seminiferous tubules
 Enhances spermatogenesis
 Sertoli cells secrete inhibin
o Reduces FSH secretion
 LH stimulates Leydig cells
 Secrete testosterone
 Negative feedback on anterior pituitary and hypothalamus





- Describe spermatogenesis.
o Spermatogenesis
 Spermatogenesis
 Stimulated by testosterone, enhanced by FSH
o Also stimulated by estrogen
 At puberty, males have 1-2K spermatogonia (germ cells)
 Spermatogonium undergoes mitosis to make primary spermatocyte
o Prevents exhaustion of spermatogonia
 Primary spermatocyte (Spermatogenesis) undergoes meiosis I to
produce 2 secondary spermatocytes
 Each secondary spermatocyte undergoes meiosis II to produce
 Conversion of spermatids to spermatozoa (sperm) (Spermiogenesis)
o Develop acrosome
 Contains digestive enzymes
o Grows midpiece
 Filled with mitochondria
o Develop flagellum (axoneme)
o Sertoli cells remove cytoplasm
o DNA compacts
 Spermatozoa are released into lumen of seminiferous tubules

, o Non-motile and immature




o
- Describe spermiogenesis.
o Spermiogenesis
 Spermatogenesis
 Stimulated by testosterone, enhanced by FSH
o Also stimulated by estrogen
 At puberty, males have 1-2K spermatogonia (germ cells)
 Spermatogonium undergoes mitosis to make primary spermatocyte
o Prevents exhaustion of spermatogonia
 Primary spermatocyte (Spermatogenesis) undergoes meiosis I to
produce 2 secondary spermatocytes
 Each secondary spermatocyte undergoes meiosis II to produce
 Conversion of spermatids to spermatozoa (sperm) (Spermiogenesis)
o Develop acrosome
 Contains digestive enzymes
o Grows midpiece
 Filled with mitochondria
o Develop flagellum (axoneme)
o Sertoli cells remove cytoplasm
o DNA compacts