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NR507/ NR 507 MIDTERM EXAM (LATEST 2024/ 2025) ADVANCED PATHOPHYSIOLOGY COMPLETE GUIDE WITH QUESTIONS AND VERIFIED ANSWERS 100% CORRECT GRADE A+

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1. Which of the following are considered the "first responders" of the innate immune system? Neutrophi

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NR507/ NR 507 MIDTERM
EXAM (LATEST 2024/ 2025)
ADVANCED
PATHOPHYSIOLOGY
COMPLETE GUIDE WITH
QUESTIONS AND VERIFIED
ANSWERS 100% CORRECT
GRADE A+ CHAMBERLAIN
[Document subtitle]




[DATE]
[COMPANY NAME]
[Company address]

,Section 1: Immune System and Hypersensitivity

1. Which of the following are considered the "first responders" of the innate
immune system?
Neutrophils

2. Allergic contact dermatitis is an example of hypersensitivity reaction
Type 4

3. Hives (urticaria) are an example of a:
Type 1 hypersensitivity reaction

4. Which of the assessment findings would be expected with urticaria?
Eosinophilia

5. Underlying pathology for hay fever?
Mast cell degranulation

6. Chronic granulomatous disease of Childhood includes:
DiGeorge Syndrome, Job Syndrome, Common Variable Immunodeficiency,
Familial Mediterranean fever, Primary Immunodeficiencies

7. HIV can lead to complications such as:
Pneumocystis Carinii Pneumonia, Sinus Infection, Lung Cancer, Secondary
Immunodeficiencies

8. Which CD4 count should be prescribed in HIV treatment regimen?
Under 500

9. Before any invasive procedure, what should be administered to immune-
compromised individuals?
Prophylactic antimicrobial drugs

10. Immunodeficiency puts individuals most at risk for which 2 conditions?
Cancer and Opportunistic infections

11. Treatment option for HIV?
Highly active antiretroviral therapy (HAART)

12. Which of the following assessment findings support a diagnosis of
Rheumatoid Arthritis?
Swollen metacarpophalangeal joints

13. True or False: T-cells, B-cells, and autoantibodies can be involved in
autoimmune diseases.
True

, 14. Best describes the symptoms of Systemic Lupus Erythematosus (SLE):
Tissue inflammation, vasculitis, rash, tissue inflammation

15. The process where a normal cell becomes a cancer cell:
Cell transformation

16. A common event during cellular reproduction resulting in the constant
occurrence of isolated cancer cells:
Cell transformation

17. An immature, undifferentiated (generic) cell that is capable of infinite
cellular division when stimulated:
Stem cell

18. The process whereby the stem cell undergoes the process of cell division
(24-hour cycle) average:
Cell cycle

19. Anaphylaxis is what type of hypersensitivity reaction?
Type 1

20. Type 2 (Cytotoxic) hypersensitivity reactions are mediated by:
IgG or IgM

21. Damage occurs with ABO incompatibility because:
Complement damages RBC membrane causing cell lysis

22. The diagnosis for an individual who presents to the office with sudden
swollen lips and eyes, shortness of breath and throat tightness after a bee
sting is:
Anaphylaxis

23. An example of a primary immunodeficiency is:
Chronic Granulomatous Disease

24. A predominant cause of secondary immune deficiencies worldwide:
Malnutrition

25. Which of the following is an autoimmune disease?
Systemic Lupus Erythematosus (SLE)

26. An example of a secondary immunodeficiency is:
Pneumocystis Carinii

27. True or False: Primary immunodeficiency is less common and occurs due to
a defect on the development of the immune system.
True

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