Karch's Focus on Pharmacology 8th Ed.
| Chapter 57
A client arrives at the walk-in clinic reporting vomiting and a burning sensation in the
mid-epigastric region. The nurse suspects that the client has peptic ulcer disease. Which is a
potential cause of peptic ulcer disease? - ANS-Infection with H. pylori
\A female client has GERD and is taking ranitidine (Zantac). She continues to have gastric
discomfort and asks whether she can take an antacid. Which is an appropriate response by
the nurse? - ANS-"Yes, but be sure to wait at least 2 hours to take the antacid after you take
the ranitidine."
Rationale:
If both ranitidine and antacids are prescribed, give them at least 2 hours apart to prevent
decreased absorption of ranitidine. The nurse should advise the patient to wait at least 2
hours between doses and to take the antacid after the ranitidine. The other three statements
are not true.
\A female client presents to the health care provider's office with increasing stomach acidity.
She self-administers calcium antacids. She notes that she seems to be having more issues
with stomach acid, so she has been taking the calcium antacids more frequently. The nurse
suspects that this may have caused what to occur in this client? - ANS-Rebound acidity
\A nurse is providing education to a 23-year-old female client who has been prescribed
misoprostol. What instruction should the nurse include in the teaching? - ANS-Use effective
contraceptive measures.
\A nurse is reviewing information about proton pump inhibitors. The nurse recognizes that
which of the following is available as an over-the-counter agent? - ANS-Omeprazole
(Prilosec)
Rationale:
Omeprazole is available over the counter; lansoprazole, rabeprazole, and esomeprazole are
prescription medications.
\Client teaching should include what instruction about antacids? - ANS-Take antacid 1 hour
before other medications.
\Ranitidine and cimetidine are both H2RAs used in the treatment of peptic ulcer disease. Of
the two, ranitidine is preferred in critically ill clients because it is less likely to: - ANS-interfere
with the metabolism of other drugs.
\The client has a magnesium-based antacid prescribed for administration before meals. The
nurse knows to withhold the medication if the client exhibits what? - ANS-Renal dysfunction
\The nursing instructor is discussing the use of histamine2 receptor antagonists in the
treatment of peptic ulcer disease. According to the instructor, which is a typical dosing
schedule of famotidine during the first few weeks of treatment for gastric ulcer in patients
with normal renal function? - ANS-20 mg bid
Rationale:
| Chapter 57
A client arrives at the walk-in clinic reporting vomiting and a burning sensation in the
mid-epigastric region. The nurse suspects that the client has peptic ulcer disease. Which is a
potential cause of peptic ulcer disease? - ANS-Infection with H. pylori
\A female client has GERD and is taking ranitidine (Zantac). She continues to have gastric
discomfort and asks whether she can take an antacid. Which is an appropriate response by
the nurse? - ANS-"Yes, but be sure to wait at least 2 hours to take the antacid after you take
the ranitidine."
Rationale:
If both ranitidine and antacids are prescribed, give them at least 2 hours apart to prevent
decreased absorption of ranitidine. The nurse should advise the patient to wait at least 2
hours between doses and to take the antacid after the ranitidine. The other three statements
are not true.
\A female client presents to the health care provider's office with increasing stomach acidity.
She self-administers calcium antacids. She notes that she seems to be having more issues
with stomach acid, so she has been taking the calcium antacids more frequently. The nurse
suspects that this may have caused what to occur in this client? - ANS-Rebound acidity
\A nurse is providing education to a 23-year-old female client who has been prescribed
misoprostol. What instruction should the nurse include in the teaching? - ANS-Use effective
contraceptive measures.
\A nurse is reviewing information about proton pump inhibitors. The nurse recognizes that
which of the following is available as an over-the-counter agent? - ANS-Omeprazole
(Prilosec)
Rationale:
Omeprazole is available over the counter; lansoprazole, rabeprazole, and esomeprazole are
prescription medications.
\Client teaching should include what instruction about antacids? - ANS-Take antacid 1 hour
before other medications.
\Ranitidine and cimetidine are both H2RAs used in the treatment of peptic ulcer disease. Of
the two, ranitidine is preferred in critically ill clients because it is less likely to: - ANS-interfere
with the metabolism of other drugs.
\The client has a magnesium-based antacid prescribed for administration before meals. The
nurse knows to withhold the medication if the client exhibits what? - ANS-Renal dysfunction
\The nursing instructor is discussing the use of histamine2 receptor antagonists in the
treatment of peptic ulcer disease. According to the instructor, which is a typical dosing
schedule of famotidine during the first few weeks of treatment for gastric ulcer in patients
with normal renal function? - ANS-20 mg bid
Rationale:
