Chapter 16: Musculoskeletal Disorders
1. Polypharmacy is a primary predictor for any undesired or unwanted consequences that can occur
because of taking medications. Which is of the following is the correct term for these undesired or
unwanted consequences?
1. Adverse drug reaction (ADR)
2. Prototype drug
3. Adverse drug event
4. Schedule II drugs - 1. Answer: 1
Page: 470
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1.
ADR is a reaction attributed to the drug. It is any undesired or unwanted consequence that occurs
because of taking medications.
2.
A prototype drug is the original drug model from which other medications in a pharmacological class
have been developed.
3.
An adverse drug event is any event that occurs during treatment and is not necessarily caused by the
drug itself. It is a side effect that was revealed after usage of the drug and is reported by the patient or
the doctor who has personal experience with the event.
4.
Schedule II drugs are drugs with abuse potential, and psychic and physical dependence liability.
2. Which of the following is related to the incidence of gastric acidity declining with age
because of decreased intestinal blood flow?
1. Drug metabolism
2. Drug distribution
3. Drug absorption
4. Drug elimination - 2. Answer: 3
Page:
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1.
Drug metabolism is affected with decreased liver size and blood flow, which can result in decreased
first-pass metabolism. Drug activity for some medications is prolonged because drugs are metabolized
, and eliminated more slowly.
2.
Drug distribution is affected by aging, particularly in individuals of smaller body size, those who have
decreased body water, and those with higher body fat.
3.
Drug absorption is affected when gastric acidity declines with age because of decreased intestinal
blood flow and fewer absorbing cells in the gastrointestinal (GI) tract. It is also affected with the
presence of food and other drugs in the stomach at the same time.
1. Polypharmacy is a primary predictor for any undesired or unwanted consequences that can occur
because of taking medications. Which is of the following is the correct term for these undesired or
unwanted consequences?
1. Adverse drug reaction (ADR)
2. Prototype drug
3. Adverse drug event
4. Schedule II drugs - 1. Answer: 1
Page: 470
Feedback
1.
ADR is a reaction attributed to the drug. It is any undesired or unwanted consequence that occurs
because of taking medications.
2.
A prototype drug is the original drug model from which other medications in a pharmacological class
have been developed.
3.
An adverse drug event is any event that occurs during treatment and is not necessarily caused by the
drug itself. It is a side effect that was revealed after usage of the drug and is reported by the patient or
the doctor who has personal experience with the event.
4.
Schedule II drugs are drugs with abuse potential, and psychic and physical dependence liability.
2. Which of the following is related to the incidence of gastric acidity declining with age
because of decreased intestinal blood flow?
1. Drug metabolism
2. Drug distribution
3. Drug absorption
4. Drug elimination - 2. Answer: 3
Page:
Feedback
1.
Drug metabolism is affected with decreased liver size and blood flow, which can result in decreased
first-pass metabolism. Drug activity for some medications is prolonged because drugs are metabolized
, and eliminated more slowly.
2.
Drug distribution is affected by aging, particularly in individuals of smaller body size, those who have
decreased body water, and those with higher body fat.
3.
Drug absorption is affected when gastric acidity declines with age because of decreased intestinal
blood flow and fewer absorbing cells in the gastrointestinal (GI) tract. It is also affected with the
presence of food and other drugs in the stomach at the same time.
