NAPLEX Review
What is the equation for corrected phenytoin? - Answer-CP= measured serum phenytoin/(0.2*albumin)
+0.1
What is the principle intracellular cation? - Answer-potassium
Principle extracellular is Sodium
How many mL in a teaspoon? - Answer-5 mL
how many mL in a tablespoon - Answer-15 mL
how many mL in a cup? - Answer-240 mL
how many mL in an ounce? - Answer-29.6 mL
how many mL in a pint? - Answer-473 mL
how many mL in a gallon? - Answer-3785 mL
,How do we calculate mols or mmols of a substance? - Answer-mol= g/MW
mmol= mg/MW
How many mg are in one grain? - Answer-65 mg/grain
How many lbs in a kg? - Answer-2.2lbs/kg
What is the conversion of aminophylline to theophylline? - Answer-we multiply the aminophylline by 0.8
to get the equivalent theophylline
What is the conversion of theophylline to aminophylline? - Answer-divide the amount of theophylline by
0.8 to get the equivalent aminophylline
How do we get the ratio strength from the percent strength? - Answer-ratio strength= 100/% strength
How do we get the percent strength from the ratio strength? - Answer-% strength= 100/ratio strength
How do we convert PPM to percent strength? - Answer--PPM to % strength, move decimal left 4 places
-% strength to PPM, move decimal place right 4 places
specific gravity - Answer-SG= grams of substance/mL
mEq - Answer-mEq= mg x valence/MW
Which chemicals have 2 valences? - Answer-Calcium carbonate
Calcium chloride
,Ferrous sulfate
Magnesium sulfate
mOsmol/L - Answer-mOsmol/L= [wt of substance (g/L)/MW (g/mole)] x number of particles x 1000
Equation for anion gap` - Answer-Na - (Cl + Bicarbonate)
How much elemental calcium is found in calcium carbonate and calcium citrate? - Answer-40% in
carbonate
20% in citrate
How much elemental Iron is in ferrous fumarate, ferrous sulfate, and ferrous gluconate? - Answer-
fumarate: 108 mg
sulfate: 65 mg of 325mg (20%)
gluconate 35 mg
How is absolute neutrophil count calculated? - Answer-ANC= WBC x [(%segs + %bands)/100]
What is the formula to determine a patient's total energy expenditure? - Answer-TEE= BEE x activity
factor X stress factor
What is the equation to find pH of a weak acid? - Answer-pH = pKa + log(salt/acid)
What is the equation to find pH of a weak base? - Answer-pH = (pKw - pKb) + log(base/salt)
what can we tell about ionization of acids from the pH and the pKa? - Answer-pH > pKa more acid is
ionized
, pH = pKa ionized and unionized are equal
pH < pKa more acid is unionized
An ionized drug is more soluble but cannot easily cross lipid membranes and vice versa
How are the ABG measurements written out on the exam? - Answer-pH/pCO2/pO2/HCO3/O2
What are the normal values for pH, HCO3, and pCO2? - Answer-pH = 7.35-7.45
HCO3 = 38-42
pCO2 = 22-28
When adding calcium and phosphate to TPN what should be considered? - Answer--Use calcium
gluconate over calcium chloride because it is less reactive and a lower rate of precipitation.
-Add phosphate first then add calcium at the end of the prep
-when added together don't exceed 45 mEq/L
BMI - Answer-weight in kg/height in meter^2
BSA - Answer-BSA = SQR [weight(kg) x height (cm)/3600]
How many kcals are in 10%, 20%, and 30% intravenous fat emulsions? How much fat is needed for TPN?
- Answer-10% = 1.1 kcal/mL
20% = 2 kcal/mL
30% = 3 kcal/mL
Fat for TPN = 9 kcal/gram
What is the equation for corrected phenytoin? - Answer-CP= measured serum phenytoin/(0.2*albumin)
+0.1
What is the principle intracellular cation? - Answer-potassium
Principle extracellular is Sodium
How many mL in a teaspoon? - Answer-5 mL
how many mL in a tablespoon - Answer-15 mL
how many mL in a cup? - Answer-240 mL
how many mL in an ounce? - Answer-29.6 mL
how many mL in a pint? - Answer-473 mL
how many mL in a gallon? - Answer-3785 mL
,How do we calculate mols or mmols of a substance? - Answer-mol= g/MW
mmol= mg/MW
How many mg are in one grain? - Answer-65 mg/grain
How many lbs in a kg? - Answer-2.2lbs/kg
What is the conversion of aminophylline to theophylline? - Answer-we multiply the aminophylline by 0.8
to get the equivalent theophylline
What is the conversion of theophylline to aminophylline? - Answer-divide the amount of theophylline by
0.8 to get the equivalent aminophylline
How do we get the ratio strength from the percent strength? - Answer-ratio strength= 100/% strength
How do we get the percent strength from the ratio strength? - Answer-% strength= 100/ratio strength
How do we convert PPM to percent strength? - Answer--PPM to % strength, move decimal left 4 places
-% strength to PPM, move decimal place right 4 places
specific gravity - Answer-SG= grams of substance/mL
mEq - Answer-mEq= mg x valence/MW
Which chemicals have 2 valences? - Answer-Calcium carbonate
Calcium chloride
,Ferrous sulfate
Magnesium sulfate
mOsmol/L - Answer-mOsmol/L= [wt of substance (g/L)/MW (g/mole)] x number of particles x 1000
Equation for anion gap` - Answer-Na - (Cl + Bicarbonate)
How much elemental calcium is found in calcium carbonate and calcium citrate? - Answer-40% in
carbonate
20% in citrate
How much elemental Iron is in ferrous fumarate, ferrous sulfate, and ferrous gluconate? - Answer-
fumarate: 108 mg
sulfate: 65 mg of 325mg (20%)
gluconate 35 mg
How is absolute neutrophil count calculated? - Answer-ANC= WBC x [(%segs + %bands)/100]
What is the formula to determine a patient's total energy expenditure? - Answer-TEE= BEE x activity
factor X stress factor
What is the equation to find pH of a weak acid? - Answer-pH = pKa + log(salt/acid)
What is the equation to find pH of a weak base? - Answer-pH = (pKw - pKb) + log(base/salt)
what can we tell about ionization of acids from the pH and the pKa? - Answer-pH > pKa more acid is
ionized
, pH = pKa ionized and unionized are equal
pH < pKa more acid is unionized
An ionized drug is more soluble but cannot easily cross lipid membranes and vice versa
How are the ABG measurements written out on the exam? - Answer-pH/pCO2/pO2/HCO3/O2
What are the normal values for pH, HCO3, and pCO2? - Answer-pH = 7.35-7.45
HCO3 = 38-42
pCO2 = 22-28
When adding calcium and phosphate to TPN what should be considered? - Answer--Use calcium
gluconate over calcium chloride because it is less reactive and a lower rate of precipitation.
-Add phosphate first then add calcium at the end of the prep
-when added together don't exceed 45 mEq/L
BMI - Answer-weight in kg/height in meter^2
BSA - Answer-BSA = SQR [weight(kg) x height (cm)/3600]
How many kcals are in 10%, 20%, and 30% intravenous fat emulsions? How much fat is needed for TPN?
- Answer-10% = 1.1 kcal/mL
20% = 2 kcal/mL
30% = 3 kcal/mL
Fat for TPN = 9 kcal/gram
