1|Page
NURS 8024 PHARM EXAM 3 (ANTIMICROBIAL PART
2) 2025| BRAND NEW ACTUAL EXAM WITH 100%
VERIFIED QUESTIONS AND CORRECT SOLUTIONS|
GUARANTEED VALUE PACK| ACE YOUR GRADES.
Bacterial protein synthesis inhibitors - (answers)Clindamycin
Clindamycin - (answers)Time dependent killing
Inhibits protein synthesis
Bacteriostatic
90% bioavailability
Clindamycin mechanism of resistance - (answers)Altered target sites
Active efflux (pushes drug out of the cell)
Clindamycin ADE - (answers)GI upset
Skin rash
Neutropenia
Superinfections such a c diff pseudomembranous
- don't use if patient has history of c diff
Clindamycin indications - (answers)Gram positive
Prophylaxis of endocarditis in valve patients with PCN allergy
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Oxazolidinones - (answers)New class of bacterial protein synthesis inhibitors
Time dependent killing
Prevents formation of ribosome complex
Bacteriostatic & Bactericidal against strep
Linezolid - (answers)Protein synthesis inhibitor
100% bioavailability orally
30% CSF penetration
Linezolid ADE - (answers)Hematologic
Increased thrombocytopenia risk
Anemia, neutropenia, neuropathy
Optic & peripheral neuropathy
Serotonin syndrome with SSRIs
Linezolid Indications - (answers)Gram positive resistant
VRE, HCAP, CAP
Complicated skin & tissue infections
Off label use for TB
No resistance currently
NURS 8024 PHARM EXAM 3 (ANTIMICROBIAL PART
2) 2025| BRAND NEW ACTUAL EXAM WITH 100%
VERIFIED QUESTIONS AND CORRECT SOLUTIONS|
GUARANTEED VALUE PACK| ACE YOUR GRADES.
Bacterial protein synthesis inhibitors - (answers)Clindamycin
Clindamycin - (answers)Time dependent killing
Inhibits protein synthesis
Bacteriostatic
90% bioavailability
Clindamycin mechanism of resistance - (answers)Altered target sites
Active efflux (pushes drug out of the cell)
Clindamycin ADE - (answers)GI upset
Skin rash
Neutropenia
Superinfections such a c diff pseudomembranous
- don't use if patient has history of c diff
Clindamycin indications - (answers)Gram positive
Prophylaxis of endocarditis in valve patients with PCN allergy
, 2|Page
Oxazolidinones - (answers)New class of bacterial protein synthesis inhibitors
Time dependent killing
Prevents formation of ribosome complex
Bacteriostatic & Bactericidal against strep
Linezolid - (answers)Protein synthesis inhibitor
100% bioavailability orally
30% CSF penetration
Linezolid ADE - (answers)Hematologic
Increased thrombocytopenia risk
Anemia, neutropenia, neuropathy
Optic & peripheral neuropathy
Serotonin syndrome with SSRIs
Linezolid Indications - (answers)Gram positive resistant
VRE, HCAP, CAP
Complicated skin & tissue infections
Off label use for TB
No resistance currently