TEST BANK FOR CLAYTON’S BASIC PHARMACOLOGY FOR
h h h h h h
NURSES 19TH EDITIONBY MICHELLE J. WILLIHNGANZ,
h h h h h h h
SAMUEL L. GUREVITZ, BRUCE CLAYTON COMPLETE
h h h h h h
Reach me out through
, Chapter 01: Drug Definitions, Standards, and Information Sources
h h h h h h h
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
h h h h h h h h
MULTIPLE CHOICE h
1. Which name identifies a drug listed by the US Food
h h h h h h h h h
andDrug Administration (FDA)?
h h h h
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C h
The official name is the name under which a drug is listed
h h h h h h h h h h h
by the FDA. The brand name, or trademark, is the name
h h h h h h h h h h h
given to a drug by its manufacturer. The nonproprietary, or
h h h h h h h h h h
generic, name is provided by the United States Adopted
h h h h h h h h h
Names Council.
h h
DIF: Cognitive Level: Knowledge REF: p. 9 h h h h
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective
h h h h h h h
CareEnvironment TOP: Nursing Process Step: Assessment
h h CON: h h h h h
Patient Education
h h
2. Which source contains information specific to nutritional supplements?
h h h h h h h
a. USP Dictionary of USAN &International Drug Names
h h h h h h h
b. Natural Medicines Comprehensive Database h h h
c. United States Pharmacopoeia/National Formulary (USP NF)
h h h h h
d. Drug Interaction Facts h h
ANS: C h
United States Pharmacopoeia/National Formulary contains information specific to
h h h h h h h
nutritionalsupplements. USP Dictionary of USAN & International Drug Names is a
h h h h h h h h h h h h
compilation of drugnames, pronunciation guide, and possible future FDA approved drugs; it
h h h h h h h h h h h h h
does not include nutritional supplements. Natural Medicines Comprehensive Database
h h h h h h h h h
contains
h
evidence-based information on herbal medicines and herbal combination products; it does
h h h h h h h h h h
notinclude information specific to nutritional supplements. Drug Interaction Facts contains
h h h h h h h h h h h
comprehensive information on drug interaction facts; it does not include nutritional
h h h h h h h h h h h
supplements.
h
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: h h h h
3NAT: NCLEX Client Needs Category: Physiological Integrity
h h h h h h h h
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
h h h h h h h h
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
h h h h h h h h h h h h h
a. Drug Facts and Comparisons h h h
Reach me out through
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
h h h h h h h h 3
Edition
h
b. Drug Interaction Facts h h
c. Handbook on Injectable Drugs h h h
d. Martindale—The Complete Drug Reference h h h
ANS: A h
Drug Facts and Comparisons contains drug monographs that describe all drugs in
h h h h h h h h h h h
atherapeutic class. Monographs are formatted as tables to allow comparison of
h h h h h h h h h h h h
similarproducts, brand names, manufacturers, cost indices, and available dosage
h h h h h h h h h h
forms Online version is available.
h h h h h
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 h h h h h h
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
hh h h h h h h h
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
h h h h h h h h h h h
4. Which drug reference contains monographs about virtually every single-entity drug
h h h h h h h h h
availablein the United States and describes therapeutic uses of drugs, including approved
h h h h h h h h h h h h h
and unapproved uses?
h h h
a. Martindale: The Complete Drug Reference h h h h
b. AHFS Drug Information h h
c. Drug Reference h
d. Drug Facts and Comparisons h h h
ANS: B h
AHFS Drug Information contains monographs about virtually every single-entity drug
h h h h h h h h h
available in the United States and describes therapeutic uses of drugs, including approved
h h h h h h h h h h h h h
andunapproved uses.
h h h
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 h h h h h h
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
hh h h h h h h h
TOP: Nursing Process Step: Planning
h CON: Safety | Patient Education | Clinical Judgment
h h h h h h h h h h
5. Which online drug reference makes available to healthcare providers and the public a
h h h h h h h h h h h h
standard, comprehensive, up-to-date look up and downloadable resource about medicines?
h h h h h h h h h h
a. American Drug Index h h
b. American Hospital Formulary h h
c. DailyMed
d. Drug Reference h
ANS: C h
DailyMed makes available to healthcare providers and the public a standard,
h h h h h h h h h h
comprehensive,up-to-date look up and downloadable resource about medicines. The
h h h h h h h h h h
American Drug Index isnot appropriate for patient use. The American Hospital Formulary is
h h h h h h h h h h h h h h
not appropriate for patient use. The drug reference is not appropriate for patient use.
h h h h h h h h h h h h h h
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: h h h h h h h
3NAT: NCLEX Client Needs Category: Physiological Integrity
h h h h h h h h
TOP: Nursing Process Step: Implementation
h h h h
CON: Safety | Patient Education | Clinical Judgment
h h h h h h h
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
h h h h h h h h h h h h h h
a. Federal Food, Drug, and Cosmetic Act (1938) h h h h h h
b. Durham Humphrey Amendment (1952) h h h
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
h h h h h h h h 4
Edition
h
c. Controlled Substances Act (1970) h h h
d. Kefauver Harris Drug Amendment (1962) h h h h
ANS: A h
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
h h h h h h h h h h h h h h
safety of all drugs before marketing. Later amendments and acts helped tighten FDA control
h h h h h h h h h h h h h h
and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that
h h h h h h h h h h h h h h
cannot be used safely without medical supervision and restricts their sale to prescription by a
h h h h h h h h h h h h h h h
licensed practitioner. The Controlled Substances Act addresses only controlled substances
h h h h h h h h h h
andtheir categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and
h h h h h h h h h h h h
greaterdrug safety. Drug manufacturers are required to prove to the FDA the effectiveness of
h h h h h h h h h h h h h h h
their products before marketing them.
h h h h h
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 h h h h h h
OBJ: 5 hNAT: NCLEX Client Needs Category: Physiological h h h h h
IntegrityTOP: Nursing Process Step: Assessment
h h h h h h
CON: Safety | Patient Education | Evidence | Health Care Law
h h h h h h h h h h
7. Which classification does meperidine (Demerol) fall under?
h h h h h h
a. I
b. II
c. III
d. IV
ANS: B h
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead
h h h h h h h h h h h h h h h h
tosevere psychological and physical dependence. Schedule I drugs have high potential for
h h h h h h h h h h h h h
abuseand no recognized medical use. Schedule III drugs have some potential for abuse. Use
h h h h h h h h h h h h h h h
may lead to low to moderate physical dependence or high psychological dependence.
h h h h h h h h h h h h
Schedule IVdrugs have low potential for abuse. Use may lead to limited physical or
h h h h h h h h h h h h h h h
psychological dependence.
h h
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: h h h h
2NAT: NCLEX Client Needs Category: Safe, Effective Care
h h h h h h h h h
Environment
h
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
h h h h h h h h h h
8. Which action would the FDA take to expedite drug development and approval for an
h h h h h h h h h h h h h
outbreakof smallpox?
h h h
a. List smallpox as a health orphan disease.
h h h h h h
b. Omit the preclinical research phase. h h h h
c. Extend the clinical research phase. h h h h
d. Fast track the investigational drug.
h h h h
ANS: D h
Once the Investigational New Drug Application has been approved, the drug can receive
h h h h h h h h h h h h
highest priority within the agency, which is called fast tracking. A smallpox outbreak would
h h h h h h h h h h h h h h
become a priority concern in the world. Orphan diseases are not researched in a priority
h h h h h h h h h h h h h h h
manner. Preclinical research is not omitted. Extending any phase of the research would
h h h h h h h h h h h h h
meana longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical
h h h h h h h h h h h h h h h h h h
andclinical research phase have been completed in a safe manner.
h h h h h h h h h h h
DIF: Cognitive Level: Knowledge h h REF: p. 7 hhh h OBJ: 5 h
h h h h h h
NURSES 19TH EDITIONBY MICHELLE J. WILLIHNGANZ,
h h h h h h h
SAMUEL L. GUREVITZ, BRUCE CLAYTON COMPLETE
h h h h h h
Reach me out through
, Chapter 01: Drug Definitions, Standards, and Information Sources
h h h h h h h
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
h h h h h h h h
MULTIPLE CHOICE h
1. Which name identifies a drug listed by the US Food
h h h h h h h h h
andDrug Administration (FDA)?
h h h h
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C h
The official name is the name under which a drug is listed
h h h h h h h h h h h
by the FDA. The brand name, or trademark, is the name
h h h h h h h h h h h
given to a drug by its manufacturer. The nonproprietary, or
h h h h h h h h h h
generic, name is provided by the United States Adopted
h h h h h h h h h
Names Council.
h h
DIF: Cognitive Level: Knowledge REF: p. 9 h h h h
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective
h h h h h h h
CareEnvironment TOP: Nursing Process Step: Assessment
h h CON: h h h h h
Patient Education
h h
2. Which source contains information specific to nutritional supplements?
h h h h h h h
a. USP Dictionary of USAN &International Drug Names
h h h h h h h
b. Natural Medicines Comprehensive Database h h h
c. United States Pharmacopoeia/National Formulary (USP NF)
h h h h h
d. Drug Interaction Facts h h
ANS: C h
United States Pharmacopoeia/National Formulary contains information specific to
h h h h h h h
nutritionalsupplements. USP Dictionary of USAN & International Drug Names is a
h h h h h h h h h h h h
compilation of drugnames, pronunciation guide, and possible future FDA approved drugs; it
h h h h h h h h h h h h h
does not include nutritional supplements. Natural Medicines Comprehensive Database
h h h h h h h h h
contains
h
evidence-based information on herbal medicines and herbal combination products; it does
h h h h h h h h h h
notinclude information specific to nutritional supplements. Drug Interaction Facts contains
h h h h h h h h h h h
comprehensive information on drug interaction facts; it does not include nutritional
h h h h h h h h h h h
supplements.
h
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: h h h h
3NAT: NCLEX Client Needs Category: Physiological Integrity
h h h h h h h h
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
h h h h h h h h
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
h h h h h h h h h h h h h
a. Drug Facts and Comparisons h h h
Reach me out through
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
h h h h h h h h 3
Edition
h
b. Drug Interaction Facts h h
c. Handbook on Injectable Drugs h h h
d. Martindale—The Complete Drug Reference h h h
ANS: A h
Drug Facts and Comparisons contains drug monographs that describe all drugs in
h h h h h h h h h h h
atherapeutic class. Monographs are formatted as tables to allow comparison of
h h h h h h h h h h h h
similarproducts, brand names, manufacturers, cost indices, and available dosage
h h h h h h h h h h
forms Online version is available.
h h h h h
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 h h h h h h
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
hh h h h h h h h
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
h h h h h h h h h h h
4. Which drug reference contains monographs about virtually every single-entity drug
h h h h h h h h h
availablein the United States and describes therapeutic uses of drugs, including approved
h h h h h h h h h h h h h
and unapproved uses?
h h h
a. Martindale: The Complete Drug Reference h h h h
b. AHFS Drug Information h h
c. Drug Reference h
d. Drug Facts and Comparisons h h h
ANS: B h
AHFS Drug Information contains monographs about virtually every single-entity drug
h h h h h h h h h
available in the United States and describes therapeutic uses of drugs, including approved
h h h h h h h h h h h h h
andunapproved uses.
h h h
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 h h h h h h
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
hh h h h h h h h
TOP: Nursing Process Step: Planning
h CON: Safety | Patient Education | Clinical Judgment
h h h h h h h h h h
5. Which online drug reference makes available to healthcare providers and the public a
h h h h h h h h h h h h
standard, comprehensive, up-to-date look up and downloadable resource about medicines?
h h h h h h h h h h
a. American Drug Index h h
b. American Hospital Formulary h h
c. DailyMed
d. Drug Reference h
ANS: C h
DailyMed makes available to healthcare providers and the public a standard,
h h h h h h h h h h
comprehensive,up-to-date look up and downloadable resource about medicines. The
h h h h h h h h h h
American Drug Index isnot appropriate for patient use. The American Hospital Formulary is
h h h h h h h h h h h h h h
not appropriate for patient use. The drug reference is not appropriate for patient use.
h h h h h h h h h h h h h h
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: h h h h h h h
3NAT: NCLEX Client Needs Category: Physiological Integrity
h h h h h h h h
TOP: Nursing Process Step: Implementation
h h h h
CON: Safety | Patient Education | Clinical Judgment
h h h h h h h
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
h h h h h h h h h h h h h h
a. Federal Food, Drug, and Cosmetic Act (1938) h h h h h h
b. Durham Humphrey Amendment (1952) h h h
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
h h h h h h h h 4
Edition
h
c. Controlled Substances Act (1970) h h h
d. Kefauver Harris Drug Amendment (1962) h h h h
ANS: A h
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
h h h h h h h h h h h h h h
safety of all drugs before marketing. Later amendments and acts helped tighten FDA control
h h h h h h h h h h h h h h
and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that
h h h h h h h h h h h h h h
cannot be used safely without medical supervision and restricts their sale to prescription by a
h h h h h h h h h h h h h h h
licensed practitioner. The Controlled Substances Act addresses only controlled substances
h h h h h h h h h h
andtheir categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and
h h h h h h h h h h h h
greaterdrug safety. Drug manufacturers are required to prove to the FDA the effectiveness of
h h h h h h h h h h h h h h h
their products before marketing them.
h h h h h
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 h h h h h h
OBJ: 5 hNAT: NCLEX Client Needs Category: Physiological h h h h h
IntegrityTOP: Nursing Process Step: Assessment
h h h h h h
CON: Safety | Patient Education | Evidence | Health Care Law
h h h h h h h h h h
7. Which classification does meperidine (Demerol) fall under?
h h h h h h
a. I
b. II
c. III
d. IV
ANS: B h
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead
h h h h h h h h h h h h h h h h
tosevere psychological and physical dependence. Schedule I drugs have high potential for
h h h h h h h h h h h h h
abuseand no recognized medical use. Schedule III drugs have some potential for abuse. Use
h h h h h h h h h h h h h h h
may lead to low to moderate physical dependence or high psychological dependence.
h h h h h h h h h h h h
Schedule IVdrugs have low potential for abuse. Use may lead to limited physical or
h h h h h h h h h h h h h h h
psychological dependence.
h h
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: h h h h
2NAT: NCLEX Client Needs Category: Safe, Effective Care
h h h h h h h h h
Environment
h
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
h h h h h h h h h h
8. Which action would the FDA take to expedite drug development and approval for an
h h h h h h h h h h h h h
outbreakof smallpox?
h h h
a. List smallpox as a health orphan disease.
h h h h h h
b. Omit the preclinical research phase. h h h h
c. Extend the clinical research phase. h h h h
d. Fast track the investigational drug.
h h h h
ANS: D h
Once the Investigational New Drug Application has been approved, the drug can receive
h h h h h h h h h h h h
highest priority within the agency, which is called fast tracking. A smallpox outbreak would
h h h h h h h h h h h h h h
become a priority concern in the world. Orphan diseases are not researched in a priority
h h h h h h h h h h h h h h h
manner. Preclinical research is not omitted. Extending any phase of the research would
h h h h h h h h h h h h h
meana longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical
h h h h h h h h h h h h h h h h h h
andclinical research phase have been completed in a safe manner.
h h h h h h h h h h h
DIF: Cognitive Level: Knowledge h h REF: p. 7 hhh h OBJ: 5 h
