CCTN: organ, post and immunosuppress.
Exam Questions And Answers 2025 Update.
Most common diseases that require a pancreas or liver transplant - Answer✔pancreas=Type 1
diabetes. Liver= alcohol with liver changes. Cholestasis. Chronic hepatitis. Genetic diseases.
Hepatocellular carcinoma <5cm accompanied by cirrhosis. Metabolic disease.
most common diseases that require a kidney transplant - Answer✔polycstic kidney disease,
primary glomerulonephritis, HIV assoc nephropathy; glomerulonephritis; hypertension;
systemic lupus; systemic and genetic diseases
most common diseases that require a intestine transplant - Answer✔colon excretes mainly
water and can be replacedwith colostomy bag. May replace small bowel if functional failure like
unable to absorb nutrients from TPN or related to motility. Structural disease such as crohn's,
necrotizing enterocolitis; mesenteric thrombosis or stenosis.
most common diseases that require a heart transplant - Answer✔congentital heart conditions.
CHF with class 3-4 symtoms or severe o2 dependence. End-stage heart disease. Heart valve
disease. Myocarditis. Myxomas (heart tumor). Restrictive, dilated or ischemic cardiomyopathy.
Life-threatening arrhythmias.
main cause for transplant organ rejection - Answer✔from white blood cells which unable to
attack the organ as a whole attack individual cells that comprise the organ tissue which causes
tissue necrosis or newly transplanted organ. Proper HLA matching can help avoid this.
Define hyperacute, acute and chronic rejection with transplanted organs. List common
immunosuppresive drugs. - Answer✔hyperacute= wrong ABO Rh ad recipients blood clots.
Must be immediately remove to prevent death from shock. Acute=days to months after organ
transplant as a result of T-cells responding to foreign proteins from donor organ.
Immunosuppressive meds help prevent acute rejection. 60% of kidney and liver recipients
develop acute rejection. chronic rejection usually aoccurs over years and immunosuppresive
therapy is usually of no help once it has developed.
most frequent causes of post-transplant occult fever - Answer✔occult fever is elevated
temperature but cause is unknown. Month1 is usually due to complication from surgery itself
such as urinary cath infection or could be allograft rejection . Months2-6=viral infections such
1