©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11PM.
CCTN Exam Questions And Answers 2025
Update.
Most common diseases requiring pancreas transplant - Answer✔Type 1 DM without signs of
advanced diabetic nephropathy
Most common diseases requiring liver transplant - Answer✔Alcoholism
Cholestatis
Chronic Hepatitis
Genetic Diseases
Metabolic Diseases
Cholestasis - Answer✔Bile cannot flow from liver to duodenum
Causes of ESRD - Answer✔HTN
DM
glomerulonephritis
PKD
HIV
lupus
Reasons for Intestinal Transplant - Answer✔Chron's disease
Small Bowel Stenosis
Necrotizing entercolitis
Trauma
Vascular Accidents
Mesenteric thrombosis, atresia, or stenosis
1
,©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11PM.
Hirschsprung disease - Answer✔congenital megacolon with improper peristalsis resulting in
intestinal obstruction, pediatric need for transplant
Chronic intestinal pseudo-obstruction - Answer✔A rare obstructive gut motility disorder of the
muscles and nerves in the intestine, pediatric need for transplant
Pediatric indication for intestinal transplant - Answer✔Hirschsprung disease
chronic intestinal pseudo obstruction
volvulus
gastroschisis (abdominal wall herniation)
congenital atresia
necrotizing enterocolitis
trauma
short gut syndrome
Short gut syndrome - Answer✔the inability of the small intestine to adequately absorb
nutrition, fluids, and to regulate electrolytes, can be structural or functional, usually acquired
Indications for Heart Transplant - Answer✔CHF with Class 3-4 symptoms, max therapy, reduced
exercise capacity, severe O2 dependence
End stage heart disease
Myocarditis
Myxomas
Refractory angina
Restrictive, dilated, or ischemic cardiomyopathy
life-threatening V arrhythmias
Pre Transplant Diagnostic Tests - Answer✔Abdominal US
CXR
EKG
PFT
Panorex
Right heart cath (if indicated)
Pre Transplant Lab Tests - Answer✔ABO Rh
2
, ©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11PM.
Virology Screening
Panel Reactive Antibody
Human Leukocyte Antibody
Toxoplasma Screening
Cancer Screening
Osteoporosis Screening
TB Screening
Virology Screening - Answer✔determines recipients suitability for transplant and post
transplant infection risk; HIV, EBV, CMV, Hepatitis, RPR (syphilis), TB, toxoplasma, herpes
Panel Reactive Antibody (PRA) - Answer✔The percent PRA value is a measure of a patient's
level of sensitization to donor antigens. It is the percentage of cells from a panel of blood
donors against which a potential recipient's serum reacts. The PRA reflects the percentage of
the general population that a potential recipient makes antibodies (is sensitized) against. The
higher the PRA, the more sensitized a patient is to the general donor pool, and thus the more
difficult it is to find a suitable donor. A patient may become sensitized as a result of pregnancy,
a blood transfusion, or a previous transplant.
Human Leukocyte Antigen (HLA) - Answer✔Molecules found on all nucleated cells in the body
that help the immune system to recognize whether or not a cell is foreign to the body. Human
leukocyte antigens are used to predict likelihood of organ rejection, cannot test within 72 hours
of a blood transfusion, on chromosome 6
HIV patients candidate for transplant - Answer✔- CD4 cell count greater than 200cells/mm3 for
longer than 6 months
- HIV RNA are undetectable
- HIV not progressed to AIDS
- Compliance for more than 3 months
- No opportunistic infections
Absolute Contraindication to Transplant - Answer✔- Active drinker, smoker, drug user
- AIDS
- Active infection
- Cancer
- Irreversible damage to another organ
- Diverticulitis
3
CCTN Exam Questions And Answers 2025
Update.
Most common diseases requiring pancreas transplant - Answer✔Type 1 DM without signs of
advanced diabetic nephropathy
Most common diseases requiring liver transplant - Answer✔Alcoholism
Cholestatis
Chronic Hepatitis
Genetic Diseases
Metabolic Diseases
Cholestasis - Answer✔Bile cannot flow from liver to duodenum
Causes of ESRD - Answer✔HTN
DM
glomerulonephritis
PKD
HIV
lupus
Reasons for Intestinal Transplant - Answer✔Chron's disease
Small Bowel Stenosis
Necrotizing entercolitis
Trauma
Vascular Accidents
Mesenteric thrombosis, atresia, or stenosis
1
,©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11PM.
Hirschsprung disease - Answer✔congenital megacolon with improper peristalsis resulting in
intestinal obstruction, pediatric need for transplant
Chronic intestinal pseudo-obstruction - Answer✔A rare obstructive gut motility disorder of the
muscles and nerves in the intestine, pediatric need for transplant
Pediatric indication for intestinal transplant - Answer✔Hirschsprung disease
chronic intestinal pseudo obstruction
volvulus
gastroschisis (abdominal wall herniation)
congenital atresia
necrotizing enterocolitis
trauma
short gut syndrome
Short gut syndrome - Answer✔the inability of the small intestine to adequately absorb
nutrition, fluids, and to regulate electrolytes, can be structural or functional, usually acquired
Indications for Heart Transplant - Answer✔CHF with Class 3-4 symptoms, max therapy, reduced
exercise capacity, severe O2 dependence
End stage heart disease
Myocarditis
Myxomas
Refractory angina
Restrictive, dilated, or ischemic cardiomyopathy
life-threatening V arrhythmias
Pre Transplant Diagnostic Tests - Answer✔Abdominal US
CXR
EKG
PFT
Panorex
Right heart cath (if indicated)
Pre Transplant Lab Tests - Answer✔ABO Rh
2
, ©THEBRIGHT 2025 ALL RIGHTS RESERVED 11:11PM.
Virology Screening
Panel Reactive Antibody
Human Leukocyte Antibody
Toxoplasma Screening
Cancer Screening
Osteoporosis Screening
TB Screening
Virology Screening - Answer✔determines recipients suitability for transplant and post
transplant infection risk; HIV, EBV, CMV, Hepatitis, RPR (syphilis), TB, toxoplasma, herpes
Panel Reactive Antibody (PRA) - Answer✔The percent PRA value is a measure of a patient's
level of sensitization to donor antigens. It is the percentage of cells from a panel of blood
donors against which a potential recipient's serum reacts. The PRA reflects the percentage of
the general population that a potential recipient makes antibodies (is sensitized) against. The
higher the PRA, the more sensitized a patient is to the general donor pool, and thus the more
difficult it is to find a suitable donor. A patient may become sensitized as a result of pregnancy,
a blood transfusion, or a previous transplant.
Human Leukocyte Antigen (HLA) - Answer✔Molecules found on all nucleated cells in the body
that help the immune system to recognize whether or not a cell is foreign to the body. Human
leukocyte antigens are used to predict likelihood of organ rejection, cannot test within 72 hours
of a blood transfusion, on chromosome 6
HIV patients candidate for transplant - Answer✔- CD4 cell count greater than 200cells/mm3 for
longer than 6 months
- HIV RNA are undetectable
- HIV not progressed to AIDS
- Compliance for more than 3 months
- No opportunistic infections
Absolute Contraindication to Transplant - Answer✔- Active drinker, smoker, drug user
- AIDS
- Active infection
- Cancer
- Irreversible damage to another organ
- Diverticulitis
3
