NUR 431 EXAM 2 DRUGS QUESTIONS
AND ANSWERS
Anticholinergics/Cholinergics - Answer-MYASTHENIA GRAVIS
cholinergics: neostigmide (can see/pee spit/shit) bradycardia, bronchial constriction
anticholinergics: atropine (can't see/pee spit/shit)tachycardia, bronchodilation
Avonex (Interferon beta 1a/b) - Answer-MULTIPLE SCLEROSIS
injectible-interferon beta
-naturally occurring substance that inhibits pro-inflammatory WBCs from crossing BBB
(blocking pro-inflammatory t-cells decreases inflammation)
-can decrease MS relapse rate by up to 30%
-AE: flu-like reactions, liver toxicity, bone marrow suppression, depression, drug
interactions
Copaxone (Glatiramer acetate) - Answer-MULTIPLE SCLEROSIS
injectible- glatiramir acetate
-increased production of anti-inflammatory t-cells which cross the BBB and suppress
inflammation
-similar efficacy
AE: injection site reactions, post-injection reactions (flushing, palpitations, chest pain,
rash, laryngeal constriction) lasts 15 to 20 mins after injection---no treatment necessary
Ropinirole - Answer-PARKINSON'S DISEASE
-Dopamine receptor agonist for idiopathic PD
-MOA is unknown (in animals-- increases nerve impulses within the substantia nigra)
-adverse effects are similar to other drugs... long term use puts pt at increased risk of
DM and acromegaly
Neostigmine - Answer-MYASTHENIA GRAVIS
-cholinesterase inhibitor
-enhances cholinergic action by facilitating transmission of impulses across
neuromuscular junctions
-in therapeutic doses, this frug affects both muscarinic and nicotinic receptors
-enhanses gi motility: also given for constipation
-increase secretions, gi motility, urinary urgency, bradycardia, bronchial constriction,
miosis
therapeutic dose = increased muscle contraction
toxic dose = reduced contraction--- CHOLINERGIC CRISIS*
Fingolimod - Answer-MULTIPLE SCLEROSIS
(oral disease process modifier)
AND ANSWERS
Anticholinergics/Cholinergics - Answer-MYASTHENIA GRAVIS
cholinergics: neostigmide (can see/pee spit/shit) bradycardia, bronchial constriction
anticholinergics: atropine (can't see/pee spit/shit)tachycardia, bronchodilation
Avonex (Interferon beta 1a/b) - Answer-MULTIPLE SCLEROSIS
injectible-interferon beta
-naturally occurring substance that inhibits pro-inflammatory WBCs from crossing BBB
(blocking pro-inflammatory t-cells decreases inflammation)
-can decrease MS relapse rate by up to 30%
-AE: flu-like reactions, liver toxicity, bone marrow suppression, depression, drug
interactions
Copaxone (Glatiramer acetate) - Answer-MULTIPLE SCLEROSIS
injectible- glatiramir acetate
-increased production of anti-inflammatory t-cells which cross the BBB and suppress
inflammation
-similar efficacy
AE: injection site reactions, post-injection reactions (flushing, palpitations, chest pain,
rash, laryngeal constriction) lasts 15 to 20 mins after injection---no treatment necessary
Ropinirole - Answer-PARKINSON'S DISEASE
-Dopamine receptor agonist for idiopathic PD
-MOA is unknown (in animals-- increases nerve impulses within the substantia nigra)
-adverse effects are similar to other drugs... long term use puts pt at increased risk of
DM and acromegaly
Neostigmine - Answer-MYASTHENIA GRAVIS
-cholinesterase inhibitor
-enhances cholinergic action by facilitating transmission of impulses across
neuromuscular junctions
-in therapeutic doses, this frug affects both muscarinic and nicotinic receptors
-enhanses gi motility: also given for constipation
-increase secretions, gi motility, urinary urgency, bradycardia, bronchial constriction,
miosis
therapeutic dose = increased muscle contraction
toxic dose = reduced contraction--- CHOLINERGIC CRISIS*
Fingolimod - Answer-MULTIPLE SCLEROSIS
(oral disease process modifier)
