1|Page
CHEMO CERTIFICATION TEST LATEST 2025 EXAM
QUESTIONS AND CORRECT ANSWERS (VERIFIED
ANSWERS) |AGRADE
What drug classification is Ixabepilone (Ixempra)?
A. Antimetabolities
B. Misc.
C. Plant Alkaloids - (ANSWER)B
What is a normal hgb? - (ANSWER)14-18 for men
12-16 for women
Where are the most common areas of metastasis? - (ANSWER)Bone, liver, lung,
brain
What is maturation/differentiation? - (ANSWER)How well the tumor cell match
the original cells
What is proliferation/division? - (ANSWER)How quickly the cells is dividing
,2|Page
What are the pros and cons to rapid proliferation? - (ANSWER)Pros: you can hit
this Ca. hard with the treat meant and it will respond well
Con: It can divide to fast for treatment to work
What are the pros and cons of slow proliferation? - (ANSWER)Pro: You can watch
and wait because you don't need treatment right away
Cons: Can swing to fast proliferation easily and you don't start treatment right
away
Tell me about
Grade 1 differentiation - (ANSWER)Well differentiated
Confined to organ of origin
Looks like the original cell that it comes from
70-90% survival rate
Tell me about
Grade 2 Differentiation - (ANSWER)Moderately differentiated
Local spread with close nodal involvement
45-55% survival rate
Tell me about
,3|Page
Grade 3 differentiation - (ANSWER)tumor fixed with extensive nodal involvement
25% survival rate
Tell me about
Grade 4 Differentiation - (ANSWER)Mets to other organs and tissues
cannot tell where the cell originated from
<5% survival rate
The Vinca Alkaloids have which dose-limiting toxicity? - (ANSWER)Neuro-toxicity
What are some examples of how you assess for neurotoxicity? -
(ANSWER)Sensation
Ability to button a shirt
Any tingling
Eye droop
Fine motor movements
Tingling
Balance
Attention span
Concentration
, 4|Page
Etoposide (VP-16) has this known side effect with rapid transfusion -
(ANSWER)Hypotension
When administering taxanes, what is the total bilirubin requirement? -
(ANSWER)<1.2
Capecitabine (Xeloda) should not be taken with what medication and why? -
(ANSWER)Warfarin and coumadin
It increases the chance of have toxic levels of these drugs
What dose-limiting toxicity does Capecitabine (Xeloda) have? - (ANSWER)Palmar-
Plantar erythrodysesthesia (PPE)
When administering Fluorouracil (5FU) which toxicity is noted most in...
IVP
IV Infusion - (ANSWER)IVP-Myelosupression
IV Infusion- GI symptoms
CHEMO CERTIFICATION TEST LATEST 2025 EXAM
QUESTIONS AND CORRECT ANSWERS (VERIFIED
ANSWERS) |AGRADE
What drug classification is Ixabepilone (Ixempra)?
A. Antimetabolities
B. Misc.
C. Plant Alkaloids - (ANSWER)B
What is a normal hgb? - (ANSWER)14-18 for men
12-16 for women
Where are the most common areas of metastasis? - (ANSWER)Bone, liver, lung,
brain
What is maturation/differentiation? - (ANSWER)How well the tumor cell match
the original cells
What is proliferation/division? - (ANSWER)How quickly the cells is dividing
,2|Page
What are the pros and cons to rapid proliferation? - (ANSWER)Pros: you can hit
this Ca. hard with the treat meant and it will respond well
Con: It can divide to fast for treatment to work
What are the pros and cons of slow proliferation? - (ANSWER)Pro: You can watch
and wait because you don't need treatment right away
Cons: Can swing to fast proliferation easily and you don't start treatment right
away
Tell me about
Grade 1 differentiation - (ANSWER)Well differentiated
Confined to organ of origin
Looks like the original cell that it comes from
70-90% survival rate
Tell me about
Grade 2 Differentiation - (ANSWER)Moderately differentiated
Local spread with close nodal involvement
45-55% survival rate
Tell me about
,3|Page
Grade 3 differentiation - (ANSWER)tumor fixed with extensive nodal involvement
25% survival rate
Tell me about
Grade 4 Differentiation - (ANSWER)Mets to other organs and tissues
cannot tell where the cell originated from
<5% survival rate
The Vinca Alkaloids have which dose-limiting toxicity? - (ANSWER)Neuro-toxicity
What are some examples of how you assess for neurotoxicity? -
(ANSWER)Sensation
Ability to button a shirt
Any tingling
Eye droop
Fine motor movements
Tingling
Balance
Attention span
Concentration
, 4|Page
Etoposide (VP-16) has this known side effect with rapid transfusion -
(ANSWER)Hypotension
When administering taxanes, what is the total bilirubin requirement? -
(ANSWER)<1.2
Capecitabine (Xeloda) should not be taken with what medication and why? -
(ANSWER)Warfarin and coumadin
It increases the chance of have toxic levels of these drugs
What dose-limiting toxicity does Capecitabine (Xeloda) have? - (ANSWER)Palmar-
Plantar erythrodysesthesia (PPE)
When administering Fluorouracil (5FU) which toxicity is noted most in...
IVP
IV Infusion - (ANSWER)IVP-Myelosupression
IV Infusion- GI symptoms
