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Chapter 19: Blood

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Class notes on chapter 19 of A&P II on the contents of blood

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Blood CHAPTER 19

functions :
·




Transporting respiratory gases nutrients , ,
wastes ,
and hormones

Regulating pH fluid volume and temperature
·



, ,



Protection against blood loss by clotting and immune defenses
·




Blood Constituents
·


specialized fluid , , connective tissue
·
viscous and more dense than water

composed of cells (45%) suspended in a slightly warmer than body temp.
·




salt-water and protein solution called slightly alkaline pH (1 35 -1 45)
·
. .




plasma (55% ) 5 quarts 5L
·




~8 % body weight 5-6 (males 4-51
·


females
·


,


Hematocrit =
RBC/ out of total blood volume

male % is slightly higher than Female 47 % in males , 42% infemales
· ·




RBC by volume RBC outnumber WIC about 700 1
· ·

mass
:




Erythrocytes
disCS (shape
·

Biconcave

Gives RBC volume ratio
·

a large surface area to

Allows fast exchange of gases between the inside of the cell and plasma
·




Enables RBCs to form stacks
·




·
Allow RBCs to bend and flex
Anucleate , hardly any organelles
·




Precursor cells : Reticulocytes
·




120-day lifespan
·




ATP production : respiration
·
Anaerobic

Intracellular cytoskeletal protein called spectrin helps biconcave shape
·

maintain

create viscous blood
·




Hemoglobin (globular protein(
280 million molecules per RBC
·




globin chains (2 alpha and 2 beta chains(
·




Each embedded an iron atom (carries oxygen) bound to the heme pigment
·




in the center

oxyhemoglobin-oxygen bound to hemoglobin
·




Deoxyhemoglobin less than 4 oxygen atoms
·
-




carbaminohemoglobin CO2
· -




20% transport this way
·

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