EVOLVE PHARM HESI PRACTICE EXAM/EVOLVE HESI
PHARM PRACTICE EXAM 2025-2026 REAL EXAM
QUESTIONS AND CORRECT DETAILED ANSWERS (100%
CORRECT VERIFIED ANSWERS) ALREADY GRADED A+
The healthcare provider prescribes digitalis (Digoxin) for a client diagnosed with
heart failure. Which intervention should the nurse implement prior to
administering the digoxin?
A. observe the respiratory rate and depth
B. assess the serum potassium level
C. obtain the client blood pressure
D. monitor serum glucose level - ANSWER-B. Assess the serum potassium level
Rationale:
Hypokalemia (decreased serum potassium) will precipitate digitalis toxicity in
persons receiving digoxin. The nurse should monitor the client's serum potassium
levels. Blood pressure and respiratory rate will not inform the nurse about
potential safety issues with digitalis.
,Which medications should the nurse caution the client about taking while
receiving an opioid analgesic?
A. antiacids
B. benzodiazepines
C. antihypertensives
D. oral antidiabetics - ANSWER-B. benzodiazepines
Rationale
Respiratory depression increases with the concurrent use of opioid analgesics and
other central nervous system depressant agents, such as alcohol, barbiturates,
and benzodiazepines. Antacids and antidiabetic agents do not interact with
opiates to produce adverse effects. Antihypertensives may cause morphine-
induced hypotension, but should not be withheld without notifying the healthcare
provider.
The nurse is assessing the effectiveness of high dose aspirin therapy for an 88-
year-old client with arthritis. The client reports that she can't hear the nurse's
questions because her ears are ringing. What action should the nurse implement?
A. Refer the client to an audiologist for evaluation of her hearing.
B. Advise the client that this is a common side effect of aspirin therapy.
C. Notify the healthcare provider of this finding immediately.
D. Ask the client to turn off her hearing aid during the exam - ANSWER-C. notify
the healthcare provider of this finding immediately
Rationale
Tinnitus is an early sign of salicylate toxicity. The healthcare provider should be
notified immediately, and the medication discontinued
,A client asks the nurse if glipizide (Glucotrol) is an oral insulin. Which response
should the nurse provide?
A. "Yes, it is an oral insulin and has the same actions and properties as
intermediate insulin."
B. "Yes, it is an oral insulin and is distributed, metabolized, and excreted in the
same manner as insulin."
C. "No, it is not an oral insulin and can be used only when some beta cell function
is present."
D. "No, it is not an oral insulin, but it is effective for those who are resistant to
injectable insulins." - ANSWER-C. "No, it is not an oral insulin and can be used only
when some beta cell function is present."
Rationale
An effective oral form of insulin has not yet been developed because when insulin
is taken orally, it is destroyed by digestive enzymes. Glipizide (Glucotrol) is an oral
hypoglycemic agent that enhances pancreatic production of insulin
In evaluating the effects of lactulose (Cephalic), which outcome would indicate
that the drug is performing as intended?
A. An increase in urine output.
B. Two or three soft stools per day.
C. Watery, diarrhea stools.
D. Increased serum bilirubin. - ANSWER-B. Two or three soft stools per day
Rationale
, The medication lactulose can be administered for either chronic constipation or
for portal-systemic encephalopathy in clients with hepatic disease. Two to three
stools a day indicate that lactulose is performing as intended for chronic
constipation. This would also indicate it should be effective for the clients with
encephalopathy because the lactulose's action prevents absorption of ammonia in
the colon as it increases water absorption and softens the stool. The efficacy of
the use for ammonia absorption would have to be verified by a serum ammonia
level and observation of clearing of the client's mental status
An antacid (Maalox) is prescribed for a client with peptic ulcer disease. The nurse
knows that the purpose of this medication is to
A. decrease production of gastric secretions.
B. produce an adherent barrier over the ulcer.
C. maintain a gastric pH of 3.5 or above.
D. decrease gastric motor activity - ANSWER-C. maintain a gastric pH of 3.5 or
above.
Rationale
The objective of antacids is to neutralize gastric acids and keep pH of 3.5 or above
which is necessary for pepsinogen inactivity
A client is admitted to the hospital for diagnostic testing for possible myasthenia
gravis. The nurse prepares for intravenous administration of edrophonium
chloride (Tension). What is the expected outcome for this client following
administration of this pharmacologic agent?
A. Progressive difficulty with swallowing.
PHARM PRACTICE EXAM 2025-2026 REAL EXAM
QUESTIONS AND CORRECT DETAILED ANSWERS (100%
CORRECT VERIFIED ANSWERS) ALREADY GRADED A+
The healthcare provider prescribes digitalis (Digoxin) for a client diagnosed with
heart failure. Which intervention should the nurse implement prior to
administering the digoxin?
A. observe the respiratory rate and depth
B. assess the serum potassium level
C. obtain the client blood pressure
D. monitor serum glucose level - ANSWER-B. Assess the serum potassium level
Rationale:
Hypokalemia (decreased serum potassium) will precipitate digitalis toxicity in
persons receiving digoxin. The nurse should monitor the client's serum potassium
levels. Blood pressure and respiratory rate will not inform the nurse about
potential safety issues with digitalis.
,Which medications should the nurse caution the client about taking while
receiving an opioid analgesic?
A. antiacids
B. benzodiazepines
C. antihypertensives
D. oral antidiabetics - ANSWER-B. benzodiazepines
Rationale
Respiratory depression increases with the concurrent use of opioid analgesics and
other central nervous system depressant agents, such as alcohol, barbiturates,
and benzodiazepines. Antacids and antidiabetic agents do not interact with
opiates to produce adverse effects. Antihypertensives may cause morphine-
induced hypotension, but should not be withheld without notifying the healthcare
provider.
The nurse is assessing the effectiveness of high dose aspirin therapy for an 88-
year-old client with arthritis. The client reports that she can't hear the nurse's
questions because her ears are ringing. What action should the nurse implement?
A. Refer the client to an audiologist for evaluation of her hearing.
B. Advise the client that this is a common side effect of aspirin therapy.
C. Notify the healthcare provider of this finding immediately.
D. Ask the client to turn off her hearing aid during the exam - ANSWER-C. notify
the healthcare provider of this finding immediately
Rationale
Tinnitus is an early sign of salicylate toxicity. The healthcare provider should be
notified immediately, and the medication discontinued
,A client asks the nurse if glipizide (Glucotrol) is an oral insulin. Which response
should the nurse provide?
A. "Yes, it is an oral insulin and has the same actions and properties as
intermediate insulin."
B. "Yes, it is an oral insulin and is distributed, metabolized, and excreted in the
same manner as insulin."
C. "No, it is not an oral insulin and can be used only when some beta cell function
is present."
D. "No, it is not an oral insulin, but it is effective for those who are resistant to
injectable insulins." - ANSWER-C. "No, it is not an oral insulin and can be used only
when some beta cell function is present."
Rationale
An effective oral form of insulin has not yet been developed because when insulin
is taken orally, it is destroyed by digestive enzymes. Glipizide (Glucotrol) is an oral
hypoglycemic agent that enhances pancreatic production of insulin
In evaluating the effects of lactulose (Cephalic), which outcome would indicate
that the drug is performing as intended?
A. An increase in urine output.
B. Two or three soft stools per day.
C. Watery, diarrhea stools.
D. Increased serum bilirubin. - ANSWER-B. Two or three soft stools per day
Rationale
, The medication lactulose can be administered for either chronic constipation or
for portal-systemic encephalopathy in clients with hepatic disease. Two to three
stools a day indicate that lactulose is performing as intended for chronic
constipation. This would also indicate it should be effective for the clients with
encephalopathy because the lactulose's action prevents absorption of ammonia in
the colon as it increases water absorption and softens the stool. The efficacy of
the use for ammonia absorption would have to be verified by a serum ammonia
level and observation of clearing of the client's mental status
An antacid (Maalox) is prescribed for a client with peptic ulcer disease. The nurse
knows that the purpose of this medication is to
A. decrease production of gastric secretions.
B. produce an adherent barrier over the ulcer.
C. maintain a gastric pH of 3.5 or above.
D. decrease gastric motor activity - ANSWER-C. maintain a gastric pH of 3.5 or
above.
Rationale
The objective of antacids is to neutralize gastric acids and keep pH of 3.5 or above
which is necessary for pepsinogen inactivity
A client is admitted to the hospital for diagnostic testing for possible myasthenia
gravis. The nurse prepares for intravenous administration of edrophonium
chloride (Tension). What is the expected outcome for this client following
administration of this pharmacologic agent?
A. Progressive difficulty with swallowing.
