MSN 671 NEI Global Video Questions with complete solutions

MSN 671 NEI Global Video Questions with complete solutions Communication between human CNS neurons at synapses is: - Answer Chemical An example of volume neurotransmission is: - Answer Dopamine in the prefrontal cortex The direct role of transcription factors is to: - Answer Influence gene expression The term epigenetics refers to: - Answer A process determining whether a given gene is expressed or silenced Presynaptic reuptake transporters are a major method of inactivation for which of the following? - Answer Serotonin and GABA What is constitutive activity? - Answer Signal transduction when no agonist or inverse agonist is bound to the receptor. A partial agonist has what effect on neurotransmission? - Answer Net agonism when neurotransmission is deficient. Net antagonism when neurotransmission is excessive. Both of the above answers are correct Agonists cause ligand-gated ion channels to: - Answer Open more frequently Which of the following is true? - Answer Both positive and negative allosteric modulations are possible only in the presence of a neurotransmitter When voltage-sensitive sodium channels are open and activated, the flow of sodium is: - Answer Into the neuron Which of the following are involved in regulating neurotransmission via excitation-secretion coupling? - Answer Both of these which are voltage-sensitive sodium channels and voltage-sensitive calcium channels. A 21-year-old man who has just been diagnosed with schizophrenia presents with his parents. He speaks with a reserved and simple language processing style; he is able to understand and relate to simple questions but seems to get lost when the pace of the conversation between the clinician and parents accelerates. when reviewing the patient's history, what pattern of cognitive functioning prior to psychosis onset would you be most likely to find? - Answer Impaired cognitive functioning premorbidly with further decline during the prodromal phase. Dopamine (DA) receptors can be categorized as D1 like (D1 and D5 receptors) and D2 like (D2, D3, and D4 receptors). What differentiates the two groups of receptors? - Answer D1-like receptors are excitatory and D2-like receptors are inhibitory. Symptoms of schizophrenia are hypothetically attributable to malfucntioning in the: - Answer Mesocortical and mesolimbic pathways