Final Exam: NR566 / NR 566 (Latest Update 2025 /
2026) Advanced Pharmacology for Care of the Family
| Exam Questions & Answers | 100% Correct | Grade A
- Chamberlain
___________________________________________________________________
Mechanism of action of estrogen and progestin
Diffuses into cells to bind to their receptors in the cell nucleus. A hormone-
receptor complex is formed, which then binds to the target gene to alter the rate
of gene transcription
Estrogen and progestin baseline
HR
BP
Weight
Pregnancy test
Screen for breast cancer
Screen for cardiovascular disease
(estrogen-only) - TSH, triglycerides
Estrogen/progestin contraindications
Abnormal vaginal bleeding
Estrogen-dependent cancers
,Breast cancer
Hx thrombus (DVT, PE, MI, CVA) - estrogen only
Abnormal liver function
Estrogen adverse effects
- Nausea
- Breast tenderness
- Bloating/Weight gain
- Increased BP
- Thrombosis
Why should estrogen be taken with progestin in menopausal women?
If they take estrogen alone, there is an increased risk of endometrial cancer
Role of progesterone in menstrual cycle
Secreted in 2nd half of menstrual cycle. If there is no pregnancy, the levels will
decrease
Role of progesterone in pregnancy
Helps maintain pregnancy by preventing uterine contraction
Decreases GI muscle contraction (causes constipation)
Promotes breast milk production
Increases pH and suppresses pCO2
,Suppresses maternal immune system (prevents attack on fetus)
Therapeutic use of progestin
Counteracts endometrial hyperplasia caused by estrogen alone
Manages dysfunctional uterine bleeding, amenorrhea and endometriosis
Supports in vitro and pregnancy in those with corpus luteum deficiency
Progestin adverse effects
breakthrough bleeding, spotting and amenorrhea
patients should report abnormal or prolonged bleeding
What is menopause?
Loss of estrogen that occurs around age 50
Menstrual cycle becomes irregular and then ovulation eventually stops
What are the symptoms of menopause?
Hot flashes/night sweats
Atrophy of urethra (causes frequency and urgency)
Atrophy of vagina (causes dryness and pain w/ intercourse)
, Decreased libido/arousal
Memory loss and anxiety
Osteoporosis
Altered lipid metabolism (increases LDL, decreases HDL)
What is doxazosin used for?
nonselective alpha 1 blocker
treatment for benign prostatic hyperplasia (BPH)
Side effects of doxazosin
orthostatic hypotension
Beers criteria - doxazosin and terazosin
can cause hypotension, fainting and dizziness (nonselective alpha blockers)
better to give older adults tamsulosin or dutasteride
When should someone take Viagra before intercourse?
1 hour before
Nausea is common when first starting____
estrogen therapies (improves over time)
What type of drug is dutasteride?
2026) Advanced Pharmacology for Care of the Family
| Exam Questions & Answers | 100% Correct | Grade A
- Chamberlain
___________________________________________________________________
Mechanism of action of estrogen and progestin
Diffuses into cells to bind to their receptors in the cell nucleus. A hormone-
receptor complex is formed, which then binds to the target gene to alter the rate
of gene transcription
Estrogen and progestin baseline
HR
BP
Weight
Pregnancy test
Screen for breast cancer
Screen for cardiovascular disease
(estrogen-only) - TSH, triglycerides
Estrogen/progestin contraindications
Abnormal vaginal bleeding
Estrogen-dependent cancers
,Breast cancer
Hx thrombus (DVT, PE, MI, CVA) - estrogen only
Abnormal liver function
Estrogen adverse effects
- Nausea
- Breast tenderness
- Bloating/Weight gain
- Increased BP
- Thrombosis
Why should estrogen be taken with progestin in menopausal women?
If they take estrogen alone, there is an increased risk of endometrial cancer
Role of progesterone in menstrual cycle
Secreted in 2nd half of menstrual cycle. If there is no pregnancy, the levels will
decrease
Role of progesterone in pregnancy
Helps maintain pregnancy by preventing uterine contraction
Decreases GI muscle contraction (causes constipation)
Promotes breast milk production
Increases pH and suppresses pCO2
,Suppresses maternal immune system (prevents attack on fetus)
Therapeutic use of progestin
Counteracts endometrial hyperplasia caused by estrogen alone
Manages dysfunctional uterine bleeding, amenorrhea and endometriosis
Supports in vitro and pregnancy in those with corpus luteum deficiency
Progestin adverse effects
breakthrough bleeding, spotting and amenorrhea
patients should report abnormal or prolonged bleeding
What is menopause?
Loss of estrogen that occurs around age 50
Menstrual cycle becomes irregular and then ovulation eventually stops
What are the symptoms of menopause?
Hot flashes/night sweats
Atrophy of urethra (causes frequency and urgency)
Atrophy of vagina (causes dryness and pain w/ intercourse)
, Decreased libido/arousal
Memory loss and anxiety
Osteoporosis
Altered lipid metabolism (increases LDL, decreases HDL)
What is doxazosin used for?
nonselective alpha 1 blocker
treatment for benign prostatic hyperplasia (BPH)
Side effects of doxazosin
orthostatic hypotension
Beers criteria - doxazosin and terazosin
can cause hypotension, fainting and dizziness (nonselective alpha blockers)
better to give older adults tamsulosin or dutasteride
When should someone take Viagra before intercourse?
1 hour before
Nausea is common when first starting____
estrogen therapies (improves over time)
What type of drug is dutasteride?
