What is the definition of chemoprophylaxis/chemoprevention? - Answers Use of drugs, nutritional and
mineral supplements, or other natural substances by *asymptomatic* persons to prevent future
disease.
What are the 4 different chemoprophylaxis agents? - Answers Iron
Fluoride
Folic Acid
Multivitamins
What are the 2 different risk factors for developing breast cancer? - Answers Increasing age
Family history
What are the 2 medications - Answers Tamoxifen
Raloxifene
What are the risks for taking these 2 cancer drugs? - Answers Increase chance of VTE, Pumlonary
embolism, DVT, or stroke
For women who are at an *increased risk* for breast cancer and *low risk for adverse medication*
effect, should they be given risk-reducing medications? - Answers YES (toxin and tamoxifen)
When would they recommend against giving the medications? - Answers Asymptomatic women aged
≥35 years without a prior diagnosis of breast cancer who are at increased risk for the disease
What are the risk factors for breast cancer? - Answers Patient age, race/ethnicity, age at menarche, age
at first live childbirth, personal history of ductal or lobular carcinoma in situ, number of first-degree
relatives with breast cancer, personal history of breast biopsy, body mass index, menopause status or
age, breast density, estrogen and progestin use, smoking, alcohol use, physical activity, and diet
Who does the USPSTF recommend aspirin to reduce MI? - Answers Men ages 45 to 79 years
Who is recommended to take aspirin to reduce ischemic stroke? - Answers Women age 55-79 years old
What are the risk factors for men developing heart disease? - Answers age, diabetes, total cholesterol
level, HDL level, blood pressure, and smoking.
What are the risk factors for women having an ischemic stroke? - Answers age, high blood pressure,
diabetes, smoking, history of CVD, atrial fibrillation, and left ventricular hypertrophy
Should aspirin prophylaxis every be given in pregnancy? - Answers NO. Never!
,*DO NOT GIVE ASA OR NSAIDS TO PREGNANT WOMEN!!!!*
What is recommended for estrogen as a chemoprophylaxis? - Answers Esrtogen is currently approved
for relief of hot flashes, vulvar or vaginal atrophy
Lowest dose for shortest duration needed
Combined estrogen and progestin therapy decreases the risk for what? - Answers fractures in
postmenopausal women
What are the risks associated with taking estrogen therapy? - Answers stroke, invasive breast cancer,
dementia, gallbladder disease, deep venous thrombosis, and pulmonary embolism.
HRT contrindications? - Answers Prior or current breast cancer
Pregnant
Trombophlebitis
Endometrial cancer
Unevaluated abnormal vaginal bleeding
Who is screening for osteoporosis recommended for? - Answers women aged 65 years or older
younger women whose fracture risk is equal to or greater than that of a 65-year-old white woman who
has no additional risk factors
What do you do to diagnose osteoporosis? - Answers DEXA scan (dual-energy x-ray absorptiometry)
What are 3 causes of inadequate immunization? - Answers 1. systems barrier (immunizations available
and able to pay)
2. Clinician barriers (inadequate clinician knowledge)
3. Parent-patient barriers (fear of immunizations)
How are injections given? What part of the body for infants? Older children/adults? - Answers IM
injections
, anterior lateral aspect of the thigh for infants
Deltoid muscle in older children and adults
Treatment for pertussis and not up to date on immunizations? - Answers erythromycin, clarithromycin,
or azithromycin
How does Corynebacterium diphtheria present? - Answers Grayish membrane over tonsils on the back
of the tongue or the uvula
*Td* schedule for pregnant women? - Answers 27 through 36 weeks gestation.
What is the leading cause of bacterial meningitis in U.S. - Answers Streptococcus pneumoniae
What are the two major clinical syndromes of invasive pneumococcal disease? - Answers bacteremia
and meningitis
What are the Contraindications to PPSV and PCV? - Answers Allergies
Illness
Pregnant
(same for meningococcal)
What are the risk factors for developing Nisseria Meningitis? - Answers Age
Community setting
Certain medical conditions
Travel
Travelers to the meningitis belt in sub-Saharan Africa may be at risk particularly during the dry season.
What bug is meningococcal disease caused by? - Answers Neisseria meningitidis
What populations are at increased risk for meningococcal disease? - Answers college freshmen living in
dormitories
microbiologists who are routinely exposed to isolates of N. meningitdis