ANSWERS
Which respiratory disorder can worsen heart failure - Answer-Sleep apnea
Why is induction therapy given for pancreas recipients - Answer-Sometimes given to
avoid use of steroids as steroid can cause hyperglycemia
Basiliximab, campath, thymoglobulin
What to do if ATN is expected - Answer-give thymoglobulin or other induction therapy
so CNIs can be delayed as they are nephrotoxic and can increase risk of ATN
kidney functions - Answer-Excretion of metabolic end products
Control fluid balance
Produce renin to control BP
Produce erythropoietin
Maintain acid base balance
Activate vitamin D
ATN treatment - Answer-there is no treatment, wait it out it can last days to weeks
Monitor for electrolyte abnormalities or major fluid overload
Enteric drainage vs bladder drainage - Answer-enteric has less risk for fluid/electrolyte
changes post transplant
Bladder is easier to detect rejection by measuring urine amylase
Bladder: risk for dehydration, UTI, cystitis, metabolic acidosis; hematuria
Hyperglycemia post pancreas transplant - Answer-Immediately post op can indicate
thrombosis
Sometimes on insulin drip for first 24-48hr post op
Monitoring amylase levels - Answer-Drain amylase- can indicate anastomosis leak
Urine amylase- low levels in bladder trained = rejection
Daily 8 hr urine tests sent each AM
Reflux pancreatitis - Answer-In bladder drained pts, urinary retention can cause
enzymes and urine to back flow to the pancreas and cause inflammation
Sign of rejection in bladder drained pancreas - Answer-Decreased urine amylase
Increased serum amylase