Test Bank - for Understanding Pharmacology Essentials for Medication Safety, 3rd Edition by M. Linda Workman & LaCharity, All Chapters 1-32

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Chapterg01:gDruggRegulation,gActions,gandgResponses
Workmang&gLaCharity:gUnderstandinggPharmacology:gEssentialsgforgMedicationgSafety,g2ndgEdit
ion

MULTIPLEgCHOICEgB

ASICgCONCEPTS

1. Whichghealthgcaregprofessionalghasgthegmajorgresponsibilitygforgdispensinggprescribedgd
rugsgundergthegdirectiongofgagpharmacist?
a. Physician
b Nursegpractitioner
.
c. Licensedgnurse
d Pharmacygtechnician
.


ANS:g D
Thegphysiciangandgnursegpractitionerghavegthegmajorgresponsibilitygforgprescribinggdrugs,gnotgdisp
ensinggthem.gTheglicensedgnurseghasgthegprimarygresponsibilitygforgadministeringgdrugs,galthoughg
undergsomegcircumstancesgaglicensedgnursegmaygdispensegprescribedgdrugsgbutgthisgisgnotghisgorgherg
majorgresponsibilitygingdruggtherapy.gThegpharmacygtechnicianghasgthegmajorgresponsibilitygofgdis
pensinggprescribedgdrugsgundergthegdirectiongofgaglicensedgpharmacist.

DIF: CognitivegLevel:gRemembering REF: p.g3

2. Whichgtermgdescribesgthegeffectgofgagdruggthatgimprovesgbodygfunction?
a. Sidegeffect
b Intendedgaction
.
c. Adversegreaction
d Idiosyncraticgresponse
.


ANS:g B
Thegpurposegofgdruggtherapygisgtogtakegagdruggtogprevent,greduce,gorgcorrectgaghealthgproblem.gT
hisgresponsegisganygdrug’sgintendedgactiongalsogknowngasgagtherapeuticgresponse.

DIF: CognitivegLevel:gRemembering REF: p.g3

3. Whichgtypegofgdruggnamegisg“owned”gbygthegcompanygthatgmanufacturesgit?
a. Genericgname
b Chemicalgname

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.
c. Categorygname
d Tradegname
.


ANS:g D
Thegchemicalgnamegisgagdrug’sgexactgchemicalgcomposition.gTheggenericgnamegisgthegnamegassigne
dgtogthegdruggbygthegU.S.gAdoptedgNamesgCouncilgandgisgnotgownedgbyganyone.gThegcategorygnam
egrefersgtogthegtypegofgdrugg(whatgitgdoesgorgwhatgitgisgusedgfor)gandgisgnotgangactualgdruggname.gThegt
radegnameg(brandgname)gisgthegnamegprovidedgandgownedgbygagspecificgdrug’sgmanufacturer.

DIF: CognitivegLevel:gRemembering REF: p.g4

4. Whichgdruggorgdruggclassgisgag“highgalert”gdrug?
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.


ANS:g B
Aghighgalertgdruggisgonegingwhichgharmgisglikelygtogresultgifggivengatgthegwronggdose,gtogthegwronggpa
tient,gorgnotggivengtogthegcorrectgpatient.gDrugsgclassifiedgasghighgalertgdrugsgincludegpotassium,gnar
coticsg(opioids),ginsulin,gcancergchemotherapygdrugs,gandgheparing(organygdruggthatgstronglygaffects
gbloodgclotting).gPenicillin,gNSAIDs,gandgcalciumgaregnotgconsideredghighgalertgdrugs.




DIF: CognitivegLevel:gRemembering REF: p.g4

5. Whatgisgthegtermgforgagdruggthatghasgthegsamegactiongasgagnaturallygoccurringgbodygh
ormonegorgenzyme?
a. Agonist
b Blockinggagent
.
c. Chemical
d Duplicator
.


ANS:g A
Agdruggagonistgisgangextrinsicgdruggthatgactivatesgthegreceptorgsitesgofgagcellgandgmimicsgthega
ctionsgofgnaturallygoccurringgbodygsubstancesg(intrinsicgdrugs).gAgblockinggagentgisgagdrug

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antagonist.gAgchemicalgwouldgnotgnecessarilygbegagdruggatgall.gAgduplicatorgisgnotgagpharmacologicgte
rm.

DIF: CognitivegLevel:gRemembering REF: pp.g6-7

6. Whichgtermgdescribesghowgthegbodygaffectsgdruggactivity?
a. Druggpotency
b Pharmacodynamics
.
c. Therapeuticgeffect
d Pharmacokinetics
.


ANS:g D
Thegtermgpharmacokineticsgrefersgtogdruggmetabolismgandghowgthegbodygchangesgagdrug.gPharmaco
dynamicsgrefersgtoghowgagdruggworksgtogchangegbodygfunction.gDruggpotencygrefersgtoghowgstronglyg
orgtogwhatgdegreegagdruggexertsgitsgeffects.gThegtherapeuticgeffectgisgclosergtogpharmacodynamics,gme
aningghowgagdruggworksgtogchangegbodygfunction.

DIF: CognitivegLevel:gRemembering REF: p.g10

7. IngthegUnitedgStates,gwhichggroupgisgresponsiblegforgenforcinggestablishedgstandardsgforgd
ruggmanufacturing?
a. U.S.gPharmacopeia
b NationalgInstitutesgofgHealth
.
c. FoodgandgDruggAdministration
d AssociationgofgPharmaceuticalgManufacturers
.


ANS:g C
ThegstandardsgforgdruggmanufacturegaregestablishedgbygthegU.S.gPharmacopeia.gThesegstandardsgar
egenforcedgbygthegFoodgandgDruggAdministration.gNeithergthegNationalgInstitutesgofgHealthgnorgtheg
AssociationgofgPharmaceuticalgManufacturersghasganygauthoritygtogenforcegdruggstandards.

DIF: CognitivegLevel:gRemembering REF: p.g5

8. Whichgfactorgisgagmajorgdisadvantagegofgthegtransdermalgdruggdeliverygroute?
a. Onlygagprescribergcangadministergdrugsgbygthegtransdermalgroute.
b Transdermalgdrugsgmustgbegsterilegrathergthangclean.
.
c. Firstgpassgdrugglossgbygthisgroutegisgthegmostgextensive.
d Druggabsorptiongisgdependentgongadequategcirculation.

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.


ANS:g D
Oncegagtransdermalgdruggmovesgthroughgthegskin,gitgmustgentergthegbloodstreamgtogreachgitsgtargetgti
ssue.gIfgcirculationgisgpoorgtogthegareagwheregthegtransdermalgdruggisgapplied,gveryglittle,gifgany,gofgt
hegdruggwillgreachgitsgtargetgtissue.

DIF: CognitivegLevel:gRemembering REF: p.g12

9. Howgaregintrinsicgdrugsgdifferentgfromgextrinsicgdrugs?
a.Intrinsicgdrugsgaregmadegbygthegbody,gwhereasgextrinsicgdrugsgaregmadegoutsidegthegbody.
b Intrinsicgdrugsgaregadministeredgbygthegparenteralgroute,gwhereasgextrinsicgdrugsgare
. administeredgbygthegoralgroute.
c.Extrinsicgdrugsgcangonlygbegappliedgtogthegskingorgmucousgmembranes,gwhereasgintrinsicgd
rugsgaregtakenginternally.
d Extrinsicgdrugsgrequiregagprescriptiongforgadministration,gwhereasgintrinsicgdrugsgare
. availablegover-the-counter.


ANS:g A
Intrinsicgdrugsgaregtheghormones,genzymes,gandgothergchemicalsgmadegbygthegbodygthatgchangegcel
lgactivity.gExtrinsicgdrugsgaregmanufacturedgfromgchemical,ganimal,gorgplantgsourcesgandgmustghaveg
agmeansgofgenteringgthegbodygingordergtogchangegcellgactivity.

DIF: CognitivegLevel:gUnderstanding REF: p.g3

10. Agpatientgasksgwhyghisgdruggtogcontrolghighgbloodgpressureghasgonlygoneggenericgnamegandgt
wogdifferentgtradegnames.gWhatgisgyourgbestgresponse?
a. “Mostgdrugsghavegdifferentgtradegnamesgthatgindicategdifferentgdosages.”
b “Thegtwogdifferentgtradegnamesgindicategthatgonegisgagmoregpuregandgsafergdruggthangthegother.”
.
c. “Theggenericgnamegisgthegactualgofficialgdruggnamegandgthegtradegnamegisgagbrandgownedgby
agspecificgmanufacturer.”
d “Ifgyoughaveginsurance,gyougcanggetgthegtradegnamegdrug,gwhichgisgusuallygmoregexpensivegthang
. theggenericgnamedgdrug.”


ANS:g C
TheggenericgnamegisgthegnamegassignedgtogthegdruggbygthegU.S.gAdoptedgNamesgCouncilgandgisgnotg
ownedgbyganyone.gThegtradegnameg(brandgname)gisgthegnamegprovidedgandgownedgbygagspecificgdru
g’sgmanufacturer.gMoregthangonegmanufacturergcangmakegandgsellgthegsamegdruggatgthegsamegtimegun
dergagdifferentgtradegname.gRegardlessgofgtradegname,gallgdrugsgthatghavegthegsameggenericgnamegm
ustgbegalikegingtheirgchemicalgcompositiongandgstrength.

DIF: CognitivegLevel:gApplyinggorgHigher REF: pp.g3-4