Test Bank Lehne's Pharmacology
guaranteed pass for Nursing
Care, 11th Edition by Jacqueline
Burchum, Laura Rosenthal Chapter
1-112|Complete Guide A+
Chapter 1: Orientation to Pharmacology Test
Bank
1. A patient has been receiving intravenous penicillin for pneumonia for several days and begins
to complain of generalized itching. The nurse auscultates bilateral wheezing and notes a
temperature of 38.5° C (101° F). Which is the correct action by the nurse?
a. Administer the next dose and continue to evaluate the patient’s symptoms.
b. Ask the prescriber if an antihistamine can be given to relieve the itching.
c. Contact the prescriber to request an order for a chest radiograph.
d. Hold the next dose and notify the prescriber of the symptoms.
ANS: D
Pruritus and wheezing are signs of a possible allergic reaction, which can be fatal; therefore,
, the medication should not be given and the prescriber should be notified. When patients are
having a potentially serious reaction to a medication, the nurse should not continue giving the
medication. Antihistamines may help the symptoms of an allergic reaction, but the first
priority is to stop the medication. Obtaining a chest radiograph is not helpful.
DIF: Cognitive Level: Application
REF: Evolution of Nursing Responsibilities Regarding Drugs | Application of Pharmacology in Patient
Care: Identifying High-Risk Patients TOP: Nursing Process: Evaluation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
MULTIPLE RESPONSE
1. A nurse is reviewing a patient’s medical record before administering a medication. Which
factor(s) can alter the patient’s physiologic response to the drug? (Select all that apply.)
a. Ability to swallow pills
b. Age
c. Genetic factors
d. Gender
e. Height
ANS: B, C, D
Age, genetic factors, and gender all influence an individual patient’s ability to absorb,
metabolize, and excrete drugs; therefore, these factors must be assessed before a medication
is administered. A patient’s ability to swallow pills, although it may determine the way a drug
is administered, does not affect the physiologic response. Height does not affect response;
weight and the distribution of adipose tissue can affect the distribution of drugs.
DIF: Cognitive Level: Analysis
REF: Evolution of Nursing Responsibilities Regarding Drugs | Application of Pharmacology in Patient
Care: Preadministration Assessment
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
Chapter 3: Drug Regulation, Development, Names, and Information Test
Bank
MULTIPLE CHOICE
1. A nurse educator is conducting a continuing education class on pharmacology. To evaluate
the learning of the nurses in the class, the nurse educator asks, “Which drug name is a generic
drug name?” Which is the correct response?
a. Acetaminophen
b. Tylenol
c. Cipro
d. Motrin
ANS: A
Acetaminophen is the generic name. Tylenol, Cipro, and Motrin are all trade names.
DIF: Cognitive Level: Comprehension REF: Table 3-3: The Three Types of Drug Names
, TOP: Nursing Process: Diagnosis
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
2. The FDA Amendments Act (FDAAA) was passed in 2007 to address which aspect of drug
safety?
a. Allowing pharmaceutical companies to identify off-label uses of medications
approved for other uses
b. Evaluating drug safety information that emerges after a drug has been
approved and is in use
c. Expediting the approval process of the U.S. Food and Drug Administration (FDA) so
that needed drugs can get to market more quickly
d. Requiring manufacturers to notify patients before removing a drug from the market
ANS: B
The FDAAA was passed to enable the Food and Drug Administration to continue oversight of a
drug after granting it approval so that changes in labeling could be made as necessary and
postmarketing risks could be tracked and identified. A provision of the FDA Modernization Act
(FDAMA), passed in 1997, allows drug companies to promote their products for off-label uses
as long as they promise to conduct studies to support their claims. Regulations to permit
accelerated approval of drugs for life-threatening diseases were adopted in 1992 by the FDA.
The requirement that drug companies notify patients 6 months before removing a drug from
the market is a provision of the FDAMA.
DIF: Cognitive Level: Comprehension REF: Landmark Drug Legislation
TOP: Nursing Process: Evaluation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
3. A nursing student asks a nurse about pharmaceutical research and wants to know the
purpose of randomization in drug trials. The nurse explains that randomization is used to:
a. ensure that differences in outcomes are the result of treatment and not
differences in subjects.
b. compare the outcome caused by the treatment to the outcome caused by
no treatment.
c. make sure that researchers are unaware of which subjects are in which group.
d. prevent subjects from knowing which group they are in and prevent
preconception bias.
ANS: A
Randomization helps prevent allocation bias, which can occur when researchers place subjects
with desired characteristics in the study group and other subjects in the control group so that
differences in outcome are actually the result of differences in subjects and not treatment.
Comparing treatment outcome to no treatment outcome is the definition of a controlled
study. The last two options describe the use of blinding in studies; blinding ensures that
researchers or subjects (or both) are unaware of which subjects are in which group so that
preconceptions about benefits and risks cannot bias the results.
DIF: Cognitive Level: Comprehension REF: The Randomized Drug Trial
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
, 4. Someone asks a nurse about a new drug that is in preclinical testing and wants to know why it
cannot be used to treat a friend’s illness. Which statement by the nurse is correct?
a. “A drug at this stage of development can be used only in patients with serious
disease.”
b. “At this stage of drug development, the safety and usefulness of the medication
is unknown.”
c. “Clinical trials must be completed to make sure the drug is safe to use in humans.”
d. “Until postmarketing surveillance data are available, the drug cannot be used.”
ANS: B
Preclinical testing must be completed before drugs can be tested in humans. In this stage,
drugs are evaluated for toxicities, pharmacokinetic properties, and potentially useful effects.
Some drugs can be used in patients before completion of Phase III studies, but this is after
preclinical testing is complete. Clinical trials proceed in stages, and each stage has guidelines
defining how a new drug may be used and which patients may receive it. Postmarketing
surveillance takes place after a drug is in general use.
DIF: Cognitive Level: Comprehension
REF: Landmark Drug Legislation | Stages of Drug Development TOP:
Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
5. A patient asks a nurse why drugs that have been approved by the FDA still have unknown
side effects. The nurse tell the patient that:
a. testing for all side effects of a medication would be prohibitively expensive.
b. patients in drug trials often are biased by their preconceptions of a drug’s benefits.
c. researchers tend to conduct studies that will prove the benefits of their new drugs.
d. subjects in drug trials do not always represent the full spectrum of possible
patients.
ANS: D
All drug trials are limited by a relatively small group of subjects who may not have all the
characteristics of people who will be using the drug; therefore, some side effects go
undetected until the drug is in use. Although drug trials are very expensive, this is only an
indirect reason they do not detect all side effects before approval. In theory, well-designed
drug trials, using blinded studies, minimize or eliminate subject bias. Designing studies to
prove desired results is unethical.
DIF: Cognitive Level: Analysis REF: Failure to Detect All Adverse Effects
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
6. A nurse is teaching nursing students about the use of nonproprietary names for drugs.
The nurse tells them which fact about nonproprietary names?
a. They are approved by the FDA and are easy to remember.
b. They are assigned by the U.S. Adopted Names Council.
c. They clearly identify the drug’s pharmacological classification.
d. They imply the efficacy of the drug and are less complex.
guaranteed pass for Nursing
Care, 11th Edition by Jacqueline
Burchum, Laura Rosenthal Chapter
1-112|Complete Guide A+
Chapter 1: Orientation to Pharmacology Test
Bank
1. A patient has been receiving intravenous penicillin for pneumonia for several days and begins
to complain of generalized itching. The nurse auscultates bilateral wheezing and notes a
temperature of 38.5° C (101° F). Which is the correct action by the nurse?
a. Administer the next dose and continue to evaluate the patient’s symptoms.
b. Ask the prescriber if an antihistamine can be given to relieve the itching.
c. Contact the prescriber to request an order for a chest radiograph.
d. Hold the next dose and notify the prescriber of the symptoms.
ANS: D
Pruritus and wheezing are signs of a possible allergic reaction, which can be fatal; therefore,
, the medication should not be given and the prescriber should be notified. When patients are
having a potentially serious reaction to a medication, the nurse should not continue giving the
medication. Antihistamines may help the symptoms of an allergic reaction, but the first
priority is to stop the medication. Obtaining a chest radiograph is not helpful.
DIF: Cognitive Level: Application
REF: Evolution of Nursing Responsibilities Regarding Drugs | Application of Pharmacology in Patient
Care: Identifying High-Risk Patients TOP: Nursing Process: Evaluation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
MULTIPLE RESPONSE
1. A nurse is reviewing a patient’s medical record before administering a medication. Which
factor(s) can alter the patient’s physiologic response to the drug? (Select all that apply.)
a. Ability to swallow pills
b. Age
c. Genetic factors
d. Gender
e. Height
ANS: B, C, D
Age, genetic factors, and gender all influence an individual patient’s ability to absorb,
metabolize, and excrete drugs; therefore, these factors must be assessed before a medication
is administered. A patient’s ability to swallow pills, although it may determine the way a drug
is administered, does not affect the physiologic response. Height does not affect response;
weight and the distribution of adipose tissue can affect the distribution of drugs.
DIF: Cognitive Level: Analysis
REF: Evolution of Nursing Responsibilities Regarding Drugs | Application of Pharmacology in Patient
Care: Preadministration Assessment
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
Chapter 3: Drug Regulation, Development, Names, and Information Test
Bank
MULTIPLE CHOICE
1. A nurse educator is conducting a continuing education class on pharmacology. To evaluate
the learning of the nurses in the class, the nurse educator asks, “Which drug name is a generic
drug name?” Which is the correct response?
a. Acetaminophen
b. Tylenol
c. Cipro
d. Motrin
ANS: A
Acetaminophen is the generic name. Tylenol, Cipro, and Motrin are all trade names.
DIF: Cognitive Level: Comprehension REF: Table 3-3: The Three Types of Drug Names
, TOP: Nursing Process: Diagnosis
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
2. The FDA Amendments Act (FDAAA) was passed in 2007 to address which aspect of drug
safety?
a. Allowing pharmaceutical companies to identify off-label uses of medications
approved for other uses
b. Evaluating drug safety information that emerges after a drug has been
approved and is in use
c. Expediting the approval process of the U.S. Food and Drug Administration (FDA) so
that needed drugs can get to market more quickly
d. Requiring manufacturers to notify patients before removing a drug from the market
ANS: B
The FDAAA was passed to enable the Food and Drug Administration to continue oversight of a
drug after granting it approval so that changes in labeling could be made as necessary and
postmarketing risks could be tracked and identified. A provision of the FDA Modernization Act
(FDAMA), passed in 1997, allows drug companies to promote their products for off-label uses
as long as they promise to conduct studies to support their claims. Regulations to permit
accelerated approval of drugs for life-threatening diseases were adopted in 1992 by the FDA.
The requirement that drug companies notify patients 6 months before removing a drug from
the market is a provision of the FDAMA.
DIF: Cognitive Level: Comprehension REF: Landmark Drug Legislation
TOP: Nursing Process: Evaluation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
3. A nursing student asks a nurse about pharmaceutical research and wants to know the
purpose of randomization in drug trials. The nurse explains that randomization is used to:
a. ensure that differences in outcomes are the result of treatment and not
differences in subjects.
b. compare the outcome caused by the treatment to the outcome caused by
no treatment.
c. make sure that researchers are unaware of which subjects are in which group.
d. prevent subjects from knowing which group they are in and prevent
preconception bias.
ANS: A
Randomization helps prevent allocation bias, which can occur when researchers place subjects
with desired characteristics in the study group and other subjects in the control group so that
differences in outcome are actually the result of differences in subjects and not treatment.
Comparing treatment outcome to no treatment outcome is the definition of a controlled
study. The last two options describe the use of blinding in studies; blinding ensures that
researchers or subjects (or both) are unaware of which subjects are in which group so that
preconceptions about benefits and risks cannot bias the results.
DIF: Cognitive Level: Comprehension REF: The Randomized Drug Trial
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
, 4. Someone asks a nurse about a new drug that is in preclinical testing and wants to know why it
cannot be used to treat a friend’s illness. Which statement by the nurse is correct?
a. “A drug at this stage of development can be used only in patients with serious
disease.”
b. “At this stage of drug development, the safety and usefulness of the medication
is unknown.”
c. “Clinical trials must be completed to make sure the drug is safe to use in humans.”
d. “Until postmarketing surveillance data are available, the drug cannot be used.”
ANS: B
Preclinical testing must be completed before drugs can be tested in humans. In this stage,
drugs are evaluated for toxicities, pharmacokinetic properties, and potentially useful effects.
Some drugs can be used in patients before completion of Phase III studies, but this is after
preclinical testing is complete. Clinical trials proceed in stages, and each stage has guidelines
defining how a new drug may be used and which patients may receive it. Postmarketing
surveillance takes place after a drug is in general use.
DIF: Cognitive Level: Comprehension
REF: Landmark Drug Legislation | Stages of Drug Development TOP:
Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Reduction of Risk Potential
5. A patient asks a nurse why drugs that have been approved by the FDA still have unknown
side effects. The nurse tell the patient that:
a. testing for all side effects of a medication would be prohibitively expensive.
b. patients in drug trials often are biased by their preconceptions of a drug’s benefits.
c. researchers tend to conduct studies that will prove the benefits of their new drugs.
d. subjects in drug trials do not always represent the full spectrum of possible
patients.
ANS: D
All drug trials are limited by a relatively small group of subjects who may not have all the
characteristics of people who will be using the drug; therefore, some side effects go
undetected until the drug is in use. Although drug trials are very expensive, this is only an
indirect reason they do not detect all side effects before approval. In theory, well-designed
drug trials, using blinded studies, minimize or eliminate subject bias. Designing studies to
prove desired results is unethical.
DIF: Cognitive Level: Analysis REF: Failure to Detect All Adverse Effects
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
6. A nurse is teaching nursing students about the use of nonproprietary names for drugs.
The nurse tells them which fact about nonproprietary names?
a. They are approved by the FDA and are easy to remember.
b. They are assigned by the U.S. Adopted Names Council.
c. They clearly identify the drug’s pharmacological classification.
d. They imply the efficacy of the drug and are less complex.
