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Nu 578 / Nu578 Controlled Substances Unit 1 Exam. Questions With 100% Correct Answers. 100%

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What body parts/locations does the stimulation of the muscarinic receptor subtype affect? (8) What are the effects of simulation of dopamine receptors? What are cholinesterase inhibitors? What is selectivity vs non-selectivity? What are adverse effects of alpha blockers? (5) Sodium retention and increased blood volume (d/t decreased BP, body tries to compensate by retaining sodium & water to raise BP - usually diuretic is given as well in this case) What is the difference between first generation, second generation, and third generation beta blockers? What are adverse effects of beta2 blockers? (2)

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NU 578 UNIT 1 EXAM
What are the effects of a1 agonists? (5)
— DAVE doesn't pee —
Dilation of eyes
Arterioles constrict (mucous membranes, skin, viscera)
Veins constrict
Ejaculation
Contraction of prostatic capsule & contraction of trigone and sphincter (person can't
pee)




What are the effects of a1 antagonists?
-Dilation of arterioles & veins (lower BP, improve blood flow and decrease pain in
Raynaud's disease)
-Dilation of prostatic capsule (helps men with BPH)
-Prevent excess release of catecholamines (epi & nori; helps with
pheochromocytoma - a tumor that releases excess catecholamines; can be given
preop before this tumor type is removed)




What are the effects of a2 antagonists?
Allow continual release of acetylcholine (normally agonists will block the release)

, What are effects of B1 antagonists? (2)
Decreased HR, force of contraction, AV node conduction speed
No release of renin (so no increase in BP)




What are effects of B2 antagonists?
No fight or flight symptoms
(No increased HR, no dilation of vessels)




What are the effects of a2 agonists? (1)
Inhibition of neurotransmitter (epi or nori release)




What are effects of B1 agonists? (2)
Increased HR, force of contraction, AV conduction speed
Release of renin to increase BP




What two conditions are resistant to drug therapy and why?
Abscesses
Tumors

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