Pharmacology NU587-807--Unit 3 questions with
answers
Furosemide (Lasix) Adverse Effects - CORRECT ANSWERS ✔✔-Hyponatremia-
Hypochloremi-Dehydration-Hypotension
Hypokalemia-Ototoxicity-Hyperglycemia-Hyperurecemia
Furesemide (Lasix) and Thiazide Drug Interactions - CORRECT ANSWERS
✔✔Digoxin drug ,Ototoxic drugs,Potassium-Sparing Diuretics,Lithium,
Antihypertensives, NSAIDS
Loop Diuretics - CORRECT ANSWERS ✔✔Ethacrynic Acid (Edecrin)
Torsemide (Demadex)-
Bumetanide (Burinex)
Torsemide - CORRECT ANSWERS ✔✔Is approved for HTN the other Diuretics are
not
Loop Diuretic Uses - CORRECT ANSWERS ✔✔Pulm. Edema with CHF-Edema of
hepatic, cardiac, or renal origin
Loop Diuretic Actions - CORRECT ANSWERS ✔✔Blocks reabsorption of sodium
and chloride in the thick segment of the ascending loop of Henle
-Prevents passive reabsorption of water
,Thiazide Diuretic Uses - CORRECT ANSWERS ✔✔Essential HTN
-Edema-Assoc. with mild to mod. Heart failure, hepatic, and renal disease
-Diabetes Insipidus-reduces excessive production by 30-50%
-Postmenopausal Osteoporosis- promotes tubular reabsorption of calcium, and may
decrese risk of osteoporosis in post-menopausal women
Thiazide Actions - CORRECT ANSWERS ✔✔Promotes urine production by blocking
the reabsorption of Na+ and Cl- in the early segment of the distal convoluted tubule
-Retention of Na+ and Cl- causes water to be retained as well producing increased
flow of urine
Thiazide Adverse Reactions - CORRECT ANSWERS ✔✔Hyponatremia--
Hypochloremia-Dehydration-Thrombosis and embolism-Hypotension--
Hypokalemia-Hyperglycemia
Hyperurecemia--High risk for pregnancy Cx
Thiazide Diuretics - CORRECT ANSWERS ✔✔Chlorothiazide (Diuril),
Hydrochlorothiazide (HydroDIURIL), Methyclothiazide (Enduron)
Thiazide-Like Diruetics - CORRECT ANSWERS ✔✔Chlorthilidone (Thalitone),
Indapamide (Lozide), Metolazone (Zaroxolyn)
Thiazide Drugs - CORRECT ANSWERS ✔✔Drug is ineffective when GFR is less
than 15-20mL/ min
Potsssium Sparing Diuretics - CORRECT ANSWERS ✔✔Sprironolactone
(Aldactone), Triamterene( Dyrenium), Amiloride (Midamor)
, Potassium Sparing Uses - CORRECT ANSWERS ✔✔HTN
-Edema/ Severe Heart Failure—
Potassium sparing adverse effects - CORRECT ANSWERS ✔✔Hyperkalemia-
gynecomastia, menstrual irregularities, impotence, hirsutism, and deepening of the
voice.
-Benign and Malignant tumors
Potassium sparing drug interactions - CORRECT ANSWERS ✔✔Thiazide and Loop
Diuretics,Agents that raise K+ levels:
-K+ supplements-salt substitutes--other K+-sparing diuretics-ACE inhibitors-
Angiotensin receptor blockers
-direct renin inhibitors
Triamterene (Dyrenium) - CORRECT ANSWERS ✔✔direct inhibitor of the exchange
mechanism itself
-produces a decrease in Na+ reabsorption and reduction in K+ secretion.
Mannitol uses - CORRECT ANSWERS ✔✔Prophylaxis of renal failure-Reduction of
Intracranial Pressure--Reduction of Intraocular Pressure
Mannito Adverse Effects - CORRECT ANSWERS ✔✔Edema-Headache-N/V-Fluid
and electrolyte imbalances
Mannitol - CORRECT ANSWERS ✔✔SHOULD BE USED IN EXTREME CAUTION
WITH HEART DISEASE—MAY CAUSE CHF AND PULMONARY EDEMA**
answers
Furosemide (Lasix) Adverse Effects - CORRECT ANSWERS ✔✔-Hyponatremia-
Hypochloremi-Dehydration-Hypotension
Hypokalemia-Ototoxicity-Hyperglycemia-Hyperurecemia
Furesemide (Lasix) and Thiazide Drug Interactions - CORRECT ANSWERS
✔✔Digoxin drug ,Ototoxic drugs,Potassium-Sparing Diuretics,Lithium,
Antihypertensives, NSAIDS
Loop Diuretics - CORRECT ANSWERS ✔✔Ethacrynic Acid (Edecrin)
Torsemide (Demadex)-
Bumetanide (Burinex)
Torsemide - CORRECT ANSWERS ✔✔Is approved for HTN the other Diuretics are
not
Loop Diuretic Uses - CORRECT ANSWERS ✔✔Pulm. Edema with CHF-Edema of
hepatic, cardiac, or renal origin
Loop Diuretic Actions - CORRECT ANSWERS ✔✔Blocks reabsorption of sodium
and chloride in the thick segment of the ascending loop of Henle
-Prevents passive reabsorption of water
,Thiazide Diuretic Uses - CORRECT ANSWERS ✔✔Essential HTN
-Edema-Assoc. with mild to mod. Heart failure, hepatic, and renal disease
-Diabetes Insipidus-reduces excessive production by 30-50%
-Postmenopausal Osteoporosis- promotes tubular reabsorption of calcium, and may
decrese risk of osteoporosis in post-menopausal women
Thiazide Actions - CORRECT ANSWERS ✔✔Promotes urine production by blocking
the reabsorption of Na+ and Cl- in the early segment of the distal convoluted tubule
-Retention of Na+ and Cl- causes water to be retained as well producing increased
flow of urine
Thiazide Adverse Reactions - CORRECT ANSWERS ✔✔Hyponatremia--
Hypochloremia-Dehydration-Thrombosis and embolism-Hypotension--
Hypokalemia-Hyperglycemia
Hyperurecemia--High risk for pregnancy Cx
Thiazide Diuretics - CORRECT ANSWERS ✔✔Chlorothiazide (Diuril),
Hydrochlorothiazide (HydroDIURIL), Methyclothiazide (Enduron)
Thiazide-Like Diruetics - CORRECT ANSWERS ✔✔Chlorthilidone (Thalitone),
Indapamide (Lozide), Metolazone (Zaroxolyn)
Thiazide Drugs - CORRECT ANSWERS ✔✔Drug is ineffective when GFR is less
than 15-20mL/ min
Potsssium Sparing Diuretics - CORRECT ANSWERS ✔✔Sprironolactone
(Aldactone), Triamterene( Dyrenium), Amiloride (Midamor)
, Potassium Sparing Uses - CORRECT ANSWERS ✔✔HTN
-Edema/ Severe Heart Failure—
Potassium sparing adverse effects - CORRECT ANSWERS ✔✔Hyperkalemia-
gynecomastia, menstrual irregularities, impotence, hirsutism, and deepening of the
voice.
-Benign and Malignant tumors
Potassium sparing drug interactions - CORRECT ANSWERS ✔✔Thiazide and Loop
Diuretics,Agents that raise K+ levels:
-K+ supplements-salt substitutes--other K+-sparing diuretics-ACE inhibitors-
Angiotensin receptor blockers
-direct renin inhibitors
Triamterene (Dyrenium) - CORRECT ANSWERS ✔✔direct inhibitor of the exchange
mechanism itself
-produces a decrease in Na+ reabsorption and reduction in K+ secretion.
Mannitol uses - CORRECT ANSWERS ✔✔Prophylaxis of renal failure-Reduction of
Intracranial Pressure--Reduction of Intraocular Pressure
Mannito Adverse Effects - CORRECT ANSWERS ✔✔Edema-Headache-N/V-Fluid
and electrolyte imbalances
Mannitol - CORRECT ANSWERS ✔✔SHOULD BE USED IN EXTREME CAUTION
WITH HEART DISEASE—MAY CAUSE CHF AND PULMONARY EDEMA**
