CCTN Exam Study Guide Questions and Answers
Verified 100% Correct
HLA (Human leukocyte antigen)
detects protein markers (antigens) on surface of most cells, including WBC. Used to predict
likelihood of organ rejection
PRA (Panel Reactive Antibody)
from 0-99%, recipients sensitivity to donors antigen.
8 Pre-op Labs
ABO blood typing
PRA
HLA
Virology
Toxoplasmosis
CA screening
Osteoporosis screening
TB
Crossmatching
blood typing test for compatibility between donor and recipient blood
Positive Crossmatch
Signifies organ recipient has HLA antibody directed against donor tissue. Can cause early graft
rejection
Crossmatch for RENAL
prior to txp
Crossmatch for Liver
, post txp
Crossmatch for Heart, Lung, and Pancreas
usually done post txp, unless PRA is >10-15%
Paired exchange
two separate willing donors are unable to give to their intended recipients because of
incompatibility so they agree to an even exchange
Indirect exchange
living kidney donor donates to first compatible ABO on cadaver waitlist in exchange donors
original recipient gets moved to the top of the waitlist for cadaver kidney
Non-directed donation
living donor offers kidney to txp center as Good Samaritan
Autonomy
self-determination
Beneficence
putting patients safety and interest above all else
Nonmaleficence
first do no harm
Justice
treating all patients impartially
Quilty effect
a tissue lesion found on the endocardium of a heart allograft due to lymphocytic infiltration.
Has no proven clinical significance but strong association with acute rejection
Verified 100% Correct
HLA (Human leukocyte antigen)
detects protein markers (antigens) on surface of most cells, including WBC. Used to predict
likelihood of organ rejection
PRA (Panel Reactive Antibody)
from 0-99%, recipients sensitivity to donors antigen.
8 Pre-op Labs
ABO blood typing
PRA
HLA
Virology
Toxoplasmosis
CA screening
Osteoporosis screening
TB
Crossmatching
blood typing test for compatibility between donor and recipient blood
Positive Crossmatch
Signifies organ recipient has HLA antibody directed against donor tissue. Can cause early graft
rejection
Crossmatch for RENAL
prior to txp
Crossmatch for Liver
, post txp
Crossmatch for Heart, Lung, and Pancreas
usually done post txp, unless PRA is >10-15%
Paired exchange
two separate willing donors are unable to give to their intended recipients because of
incompatibility so they agree to an even exchange
Indirect exchange
living kidney donor donates to first compatible ABO on cadaver waitlist in exchange donors
original recipient gets moved to the top of the waitlist for cadaver kidney
Non-directed donation
living donor offers kidney to txp center as Good Samaritan
Autonomy
self-determination
Beneficence
putting patients safety and interest above all else
Nonmaleficence
first do no harm
Justice
treating all patients impartially
Quilty effect
a tissue lesion found on the endocardium of a heart allograft due to lymphocytic infiltration.
Has no proven clinical significance but strong association with acute rejection
