CCTN General Exam Questions with Correct
Solutions
What test do you do to determine brain death before donation? - ANSWER Apnea test
First, need to correct:
-hypothermia/hyperthermia
-hypotension (at least SBP 90)
-hypovolemia
-hypoxia
-eucopnia (goal PaCO2 = 35 - 45)
What are the 3 indications of brain death? - ANSWER 1. irreversible coma (no motor response)
2. apnea (off vent)
3. no brain stem reflexes (pupil/ocular, facial muscle, pharyngeal)
What organisms do you risk ingesting if you don't boil well water before drinking/showering? -
ANSWER -e coli
-giardia
-legionella pneumophila
-gram negative organisms
What sx do you get if you get toxoplasmosis? - ANSWER -blindness
-brain damage
What organisms do reptiles and birds carry? - ANSWER -salmonella
-chlamydia
-cryptococcus
,Which 3 populations are at risk for hypomagnesium - ANSWER -diabetics
-pregnant women
-diuretics
#1 reason for kidney dysfunction post [any] transplant? - ANSWER immunosuppressants (CNI),
a nephrotoxic med
#1 reason for hyperlipidemia post [any] transplant? - ANSWER pre existing hyperlipidemia
other reasons:
-cyclosporins (increases cholesterol AND TG). prograf not as much
-rapamycin
statins lower cholesterol but at risk of rhabdomyolysis. Check CK value for that
Post transplant med that contribute to osteoporosis? - ANSWER -steroids
-cyclosprin
-prograf
-azathioprine
-cellcept
-sirolimus
What do you take biphosphonates for? - ANSWER -to prevent loss of bone density. take if dx
with osteoporosis. take in conjunction with calcium and Vit D.
-taken in morning with full glass of water
-30 min before food
, -sit upright for 30 min after
-don't drink for 30 min after
What post tx meds contribute to post tx diabetes? - ANSWER -steroids
-cyclosporin
-prograf
goal BG < 126
What meds do you treat PTLD with? - ANSWER a. acyclovir AND
b. gangcyclovir
c. radiation therapy OR
d. surgical excision of lymph node
e. decrease immunosuppressive therapy
What does MELD consist of? - ANSWER -dialysis twice in the past week?
-creatinine
-bilirubin
-INR
-sodium
Causes of impotence in men pre transplant? What post transplant meds add to impotence post
transplant? - ANSWER -diabetes
-CAD
-HTN
Solutions
What test do you do to determine brain death before donation? - ANSWER Apnea test
First, need to correct:
-hypothermia/hyperthermia
-hypotension (at least SBP 90)
-hypovolemia
-hypoxia
-eucopnia (goal PaCO2 = 35 - 45)
What are the 3 indications of brain death? - ANSWER 1. irreversible coma (no motor response)
2. apnea (off vent)
3. no brain stem reflexes (pupil/ocular, facial muscle, pharyngeal)
What organisms do you risk ingesting if you don't boil well water before drinking/showering? -
ANSWER -e coli
-giardia
-legionella pneumophila
-gram negative organisms
What sx do you get if you get toxoplasmosis? - ANSWER -blindness
-brain damage
What organisms do reptiles and birds carry? - ANSWER -salmonella
-chlamydia
-cryptococcus
,Which 3 populations are at risk for hypomagnesium - ANSWER -diabetics
-pregnant women
-diuretics
#1 reason for kidney dysfunction post [any] transplant? - ANSWER immunosuppressants (CNI),
a nephrotoxic med
#1 reason for hyperlipidemia post [any] transplant? - ANSWER pre existing hyperlipidemia
other reasons:
-cyclosporins (increases cholesterol AND TG). prograf not as much
-rapamycin
statins lower cholesterol but at risk of rhabdomyolysis. Check CK value for that
Post transplant med that contribute to osteoporosis? - ANSWER -steroids
-cyclosprin
-prograf
-azathioprine
-cellcept
-sirolimus
What do you take biphosphonates for? - ANSWER -to prevent loss of bone density. take if dx
with osteoporosis. take in conjunction with calcium and Vit D.
-taken in morning with full glass of water
-30 min before food
, -sit upright for 30 min after
-don't drink for 30 min after
What post tx meds contribute to post tx diabetes? - ANSWER -steroids
-cyclosporin
-prograf
goal BG < 126
What meds do you treat PTLD with? - ANSWER a. acyclovir AND
b. gangcyclovir
c. radiation therapy OR
d. surgical excision of lymph node
e. decrease immunosuppressive therapy
What does MELD consist of? - ANSWER -dialysis twice in the past week?
-creatinine
-bilirubin
-INR
-sodium
Causes of impotence in men pre transplant? What post transplant meds add to impotence post
transplant? - ANSWER -diabetes
-CAD
-HTN
