Advanced Pathophysiology Exam 1
Questions With Correct Answers
A ccertain cdisease cis ccurrently cfound cin c1 cof cevery c10 cpeople cin cthe ccountry cand
c1,000 cpeople ccontract cthe cdisease cyearly. cThe cpopulation cof cthe ccountry cis
c4,500,000. cWhich cof cthe cfollowing cstatements cis ccorrect?
a. cThe cprevalence cof cthe cdisease cis c10% cand cthe cincidence cis c.02%.
b. cThe cprevalence cof cthe cdisease cis c.02% cand cthe cincidence cis c10%.
c. cNeither cis ccorrect.
d. cThere cis cinsufficient cdata c- cCORRECT cANS✔✔A
In crelation cto cdisease cdevelopment, cthe cterm c"etiology" crefers cto cwhich cof cthe
cfollowing?
a.number cof cpeople cwith cthe cdisease
b. ccause cof cthe cdisease
c. cdefinition cof cthe cdisease
d. coutcome cof cthe cdisease c- cCORRECT cANS✔✔B
Which cof cthe cfollowing cis(are) ctrue cabout c"symptoms"?
a. cobjective cand cmeasurable
b. cthe csame cas c"signs"
c. cboth cof cthe cabove
d. cneither cof cthe cabove c- cCORRECT cANS✔✔D
In c1992, cthere cwere c980 cdeaths cin ca cMidwestern ccity cwith ca cpopulation cof
c1,000,000. cAt cthe cbeginning cof cthat cyear, c900 ccases cof cAIDS cexisted cin cthis
cpopulation. cDuring cthe cyear, c250 cnew ccases cof cAIDS cwere cdiagnosed, cand c75
cpeople cdied cof cthe cdisease cin c1992.
Using cthe cdata cgiven cabove, cwhat cwas cthe cincidence crate c(per c100,000
cpopulation) cat cthe cend cof c1992 cfor cAIDS?
a. c6
b. c25
c. c88
d. c116 c- cCORRECT cANS✔✔B
What clevel cof cprevention cis ca cblood cpressure cscreening cprogram cfor chigh cschool
cstudents cwho care cpregnant?
a. cprimary
b. csecondary
,c. ctertiary c- cCORRECT cANS✔✔B
Mr. cForbes ccomplains cof c"indigestion" cand cbecomes csweaty cand cpale. cHis cwife
ctakes chim cto cthe cEmergency cDepartment cat cNorthwestern cMemorial cHospital. cA
ccardiac ccatheterization c2 cdays clater cshows cpartial cblockage cof chis cright ccoronary
cartery c(RCA).
Blockage cof cthe cright ccoronary cartery ccan clead cto cmyocardial ccell cinjury cbecause cit
cresults cin cwhich cof cthe cfollowing?
a. cbilirubin caccumulation cin cmyocardial ccells
b. calteration cin cthe cgenetic cmaterial cof cmyocardial ccells
c. creduced cenergy cproduction cin cmyocardial ccells
d. cactivation cof cthe ccomplement csystem c- cCORRECT cANS✔✔C
When cmyocardial ccells care cinjured, cthe cfunction cof cthe cNa-K cmembrane cpump
cmay cbe cimpaired. cWhich cof cthe cfollowing cmay cthen cresult?
a.intracellular csodium cwill cincrease
b. cextracellular cpotassium cwill cdecrease
c. ccell cvolume cwill cdecrease
d. call cof cthe cabove c- cCORRECT cANS✔✔A
Mr. cForbes cis cbeing cprepared cfor copen cheart csurgery cwhen che csuffers ca
cmyocardial cinfarction cin cwhich ca clarge cpart cof chis cleft cventricle chas csuffered clethal
ccell cinjury.
Mr. cForbes' cCPK-MB cand cLDH1, cenzymes cassociated cwith cmyocardial ccells, care
csignificantly celevated. cWhat cis cthe cbest cexplanation cfor cthis?
a. cIt cis ca csign cthat cnecrotic cmyocardial ccells chave creleased ctheir ccytoplasmic
ccontents cinto cthe cblood.
b. cIt cis ca csign cof creversible cfatty caccumulation cin cthe cmyocardial ccells c
c. cIt cis ca csign cthat cthe cmyocardial ccells care cundergoing chypertrophy.
d. cNone cof cthe cabove. c- cCORRECT cANS✔✔A
If ca ctissue cspecimen cof cmyocardial ccells cwere cobtained cfor cexamination cfrom cMr.
cForbes, cwhich cof cthe cfollowing cfindings cwould cindicate cirreversible ccell cinjury?
a. ccellular cswelling
b. cdecreased cATP cproduction
c. cdecreased cintracellular ccalcium
d. cdissolution cof cnuclear cmaterial c- cCORRECT cANS✔✔D
The caccumulation cof clactic cacid cthat coccurs cwith cimpaired cenergy cproduction
cresults cfrom cwhich cof cthe cfollowing?
a. cincreased cintracellular cglucose
b. cincreased canaerobic cmetabolism
c. cdecreased cmetabolic crate
d. cincreased coxidative cphosphorylation c- cCORRECT cANS✔✔B
, A cmountain cclimber cis cstranded cat c23,000 cfeet cin cthe cSwiss cAlps cand chas clost call
chis cequipment cand csupplies cin can cavalanche. cSubsequently, che csuffers ccell cinjury
cdue cto cimpaired cATP cproduction. cThe creason cfor cthe cdecrease cin cATP cis cwhich
cof cthe cfollowing?
a. cenzyme cinhibition
b. cuncoupling
c. chypoxia
d. cnone cof cthe cabove c- cCORRECT cANS✔✔C
An celderly cpatient cdevelops can cobstruction cin chis cleft cmiddle ccerebral cartery. cThe
cbrain ctissue csupplied cby cthis cartery cbecomes chypoxic. cThe cbest cexplanation cfor
cthis cis cwhich cof cthe cfollowing?
a. cthe cobstruction cresults cin cdecreased cblood cflow
b. cthe cobstruction cresults cin cdecreased chemoglobin cin cthe cblood
c. cwhile cblood cflow cstays cthe csame, cthe cobstruction creduces coxygen ccontent cin
cthe cblood
d. cnone cof cthe cabove cexplain cthe creason cfor cthe chypoxia c- cCORRECT cANS✔✔A
Increased cmobilization cand cdelivery cof cfree cfatty cacids cto cliver ccells ccan cresult cin
cfat caccumulation. cWhich cof cthe cfollowing cproblems cresults cin cincreased
cmobilization cof cfree cfatty cacids?
a. canemia
b. chepatic ctoxins
c. cstarvation
d. chypoxia c- cCORRECT cANS✔✔C
Generalized chypoxia cresults cin ca cswitch cto canaerobic cmetabolism cin ccells.
cAnaerobic cmetabolism cresults cin cwhich cof cthe cfollowing?
a. cdecreased clactic cacid cinside ccells
b. cdecreased carterial cpH
c. cmore ceffective cATP cproduction
d. cincreased cpH cinside ccells c- cCORRECT cANS✔✔B
There cis ca cdisease cof cthe cspleen, cwhich cresults cin can cexcessive cdestruction cof
cRBCs. cThis cincrease cin cRBC cdestruction ccan clead cto cwhich cof cthe cfollowing?
a. chypoxia
b. chypobilirubinemia
c. can cincrease cin cplatelets
d. call cof cthe cabove c- cCORRECT cANS✔✔A
Your cbody chas cdeveloped can cincreased cdemand cfor cthyroid chormones. cThis cwill
clead cto c____________ cof cthe cthyroid cgland.
a. catrophy
b. chypertrophy
c. cdysplasia
d. cmetaplasia c- cCORRECT cANS✔✔B
Questions With Correct Answers
A ccertain cdisease cis ccurrently cfound cin c1 cof cevery c10 cpeople cin cthe ccountry cand
c1,000 cpeople ccontract cthe cdisease cyearly. cThe cpopulation cof cthe ccountry cis
c4,500,000. cWhich cof cthe cfollowing cstatements cis ccorrect?
a. cThe cprevalence cof cthe cdisease cis c10% cand cthe cincidence cis c.02%.
b. cThe cprevalence cof cthe cdisease cis c.02% cand cthe cincidence cis c10%.
c. cNeither cis ccorrect.
d. cThere cis cinsufficient cdata c- cCORRECT cANS✔✔A
In crelation cto cdisease cdevelopment, cthe cterm c"etiology" crefers cto cwhich cof cthe
cfollowing?
a.number cof cpeople cwith cthe cdisease
b. ccause cof cthe cdisease
c. cdefinition cof cthe cdisease
d. coutcome cof cthe cdisease c- cCORRECT cANS✔✔B
Which cof cthe cfollowing cis(are) ctrue cabout c"symptoms"?
a. cobjective cand cmeasurable
b. cthe csame cas c"signs"
c. cboth cof cthe cabove
d. cneither cof cthe cabove c- cCORRECT cANS✔✔D
In c1992, cthere cwere c980 cdeaths cin ca cMidwestern ccity cwith ca cpopulation cof
c1,000,000. cAt cthe cbeginning cof cthat cyear, c900 ccases cof cAIDS cexisted cin cthis
cpopulation. cDuring cthe cyear, c250 cnew ccases cof cAIDS cwere cdiagnosed, cand c75
cpeople cdied cof cthe cdisease cin c1992.
Using cthe cdata cgiven cabove, cwhat cwas cthe cincidence crate c(per c100,000
cpopulation) cat cthe cend cof c1992 cfor cAIDS?
a. c6
b. c25
c. c88
d. c116 c- cCORRECT cANS✔✔B
What clevel cof cprevention cis ca cblood cpressure cscreening cprogram cfor chigh cschool
cstudents cwho care cpregnant?
a. cprimary
b. csecondary
,c. ctertiary c- cCORRECT cANS✔✔B
Mr. cForbes ccomplains cof c"indigestion" cand cbecomes csweaty cand cpale. cHis cwife
ctakes chim cto cthe cEmergency cDepartment cat cNorthwestern cMemorial cHospital. cA
ccardiac ccatheterization c2 cdays clater cshows cpartial cblockage cof chis cright ccoronary
cartery c(RCA).
Blockage cof cthe cright ccoronary cartery ccan clead cto cmyocardial ccell cinjury cbecause cit
cresults cin cwhich cof cthe cfollowing?
a. cbilirubin caccumulation cin cmyocardial ccells
b. calteration cin cthe cgenetic cmaterial cof cmyocardial ccells
c. creduced cenergy cproduction cin cmyocardial ccells
d. cactivation cof cthe ccomplement csystem c- cCORRECT cANS✔✔C
When cmyocardial ccells care cinjured, cthe cfunction cof cthe cNa-K cmembrane cpump
cmay cbe cimpaired. cWhich cof cthe cfollowing cmay cthen cresult?
a.intracellular csodium cwill cincrease
b. cextracellular cpotassium cwill cdecrease
c. ccell cvolume cwill cdecrease
d. call cof cthe cabove c- cCORRECT cANS✔✔A
Mr. cForbes cis cbeing cprepared cfor copen cheart csurgery cwhen che csuffers ca
cmyocardial cinfarction cin cwhich ca clarge cpart cof chis cleft cventricle chas csuffered clethal
ccell cinjury.
Mr. cForbes' cCPK-MB cand cLDH1, cenzymes cassociated cwith cmyocardial ccells, care
csignificantly celevated. cWhat cis cthe cbest cexplanation cfor cthis?
a. cIt cis ca csign cthat cnecrotic cmyocardial ccells chave creleased ctheir ccytoplasmic
ccontents cinto cthe cblood.
b. cIt cis ca csign cof creversible cfatty caccumulation cin cthe cmyocardial ccells c
c. cIt cis ca csign cthat cthe cmyocardial ccells care cundergoing chypertrophy.
d. cNone cof cthe cabove. c- cCORRECT cANS✔✔A
If ca ctissue cspecimen cof cmyocardial ccells cwere cobtained cfor cexamination cfrom cMr.
cForbes, cwhich cof cthe cfollowing cfindings cwould cindicate cirreversible ccell cinjury?
a. ccellular cswelling
b. cdecreased cATP cproduction
c. cdecreased cintracellular ccalcium
d. cdissolution cof cnuclear cmaterial c- cCORRECT cANS✔✔D
The caccumulation cof clactic cacid cthat coccurs cwith cimpaired cenergy cproduction
cresults cfrom cwhich cof cthe cfollowing?
a. cincreased cintracellular cglucose
b. cincreased canaerobic cmetabolism
c. cdecreased cmetabolic crate
d. cincreased coxidative cphosphorylation c- cCORRECT cANS✔✔B
, A cmountain cclimber cis cstranded cat c23,000 cfeet cin cthe cSwiss cAlps cand chas clost call
chis cequipment cand csupplies cin can cavalanche. cSubsequently, che csuffers ccell cinjury
cdue cto cimpaired cATP cproduction. cThe creason cfor cthe cdecrease cin cATP cis cwhich
cof cthe cfollowing?
a. cenzyme cinhibition
b. cuncoupling
c. chypoxia
d. cnone cof cthe cabove c- cCORRECT cANS✔✔C
An celderly cpatient cdevelops can cobstruction cin chis cleft cmiddle ccerebral cartery. cThe
cbrain ctissue csupplied cby cthis cartery cbecomes chypoxic. cThe cbest cexplanation cfor
cthis cis cwhich cof cthe cfollowing?
a. cthe cobstruction cresults cin cdecreased cblood cflow
b. cthe cobstruction cresults cin cdecreased chemoglobin cin cthe cblood
c. cwhile cblood cflow cstays cthe csame, cthe cobstruction creduces coxygen ccontent cin
cthe cblood
d. cnone cof cthe cabove cexplain cthe creason cfor cthe chypoxia c- cCORRECT cANS✔✔A
Increased cmobilization cand cdelivery cof cfree cfatty cacids cto cliver ccells ccan cresult cin
cfat caccumulation. cWhich cof cthe cfollowing cproblems cresults cin cincreased
cmobilization cof cfree cfatty cacids?
a. canemia
b. chepatic ctoxins
c. cstarvation
d. chypoxia c- cCORRECT cANS✔✔C
Generalized chypoxia cresults cin ca cswitch cto canaerobic cmetabolism cin ccells.
cAnaerobic cmetabolism cresults cin cwhich cof cthe cfollowing?
a. cdecreased clactic cacid cinside ccells
b. cdecreased carterial cpH
c. cmore ceffective cATP cproduction
d. cincreased cpH cinside ccells c- cCORRECT cANS✔✔B
There cis ca cdisease cof cthe cspleen, cwhich cresults cin can cexcessive cdestruction cof
cRBCs. cThis cincrease cin cRBC cdestruction ccan clead cto cwhich cof cthe cfollowing?
a. chypoxia
b. chypobilirubinemia
c. can cincrease cin cplatelets
d. call cof cthe cabove c- cCORRECT cANS✔✔A
Your cbody chas cdeveloped can cincreased cdemand cfor cthyroid chormones. cThis cwill
clead cto c____________ cof cthe cthyroid cgland.
a. catrophy
b. chypertrophy
c. cdysplasia
d. cmetaplasia c- cCORRECT cANS✔✔B
