1. Which of the following is a critical aspect of maintaining
sterility during sterile compounding?
A. Avoiding direct contact between the drug and the air
B. Wearing non-sterile gloves during preparation
C. Using alcohol-free solutions for disinfecting surfaces
D. Keeping all equipment in open trays
Answer: A) Avoiding direct contact between the drug and the air
Rationale: To maintain sterility, it is critical to avoid exposing the
drug to air, which can introduce microorganisms and particles,
compromising the preparation's sterility.
2. How should a pharmacist address a situation where a
compounded sterile preparation (CSP) has an incorrect label or is
missing necessary information?
A. Ignore the issue and dispense the preparation
B. Discard the preparation and prepare a new one with correct
labeling
C. Ask the patient to fill out the missing information
D. Submit the preparation to testing
Answer: B) Discard the preparation and prepare a new one with
correct labeling
,Rationale: Proper labeling is essential for patient safety, and any
CSP with incorrect or missing labeling should be discarded and
re-prepared with the correct information.
3. What is the purpose of performing an initial certification of the
compounding area?
A. To verify that equipment is working properly
B. To assess air quality, temperature, and other environmental
factors
C. To ensure that compounding personnel are following proper
hand hygiene protocols
D. To check that all supplies are in stock
Answer: B) To assess air quality, temperature, and other
environmental factors
Rationale: Initial certification is performed to ensure that the
compounding area meets all required environmental standards,
such as air quality and temperature control, before compounding
begins.
4. When should a compounding pharmacy use a Class II Biological
Safety Cabinet (BSC)?
A. For preparing non-sterile preparations
B. For preparing sterile preparations with risk of exposure to
hazardous drugs
, C. Only for testing new products
D. For packaging non-sterile compounds
Answer: B) For preparing sterile preparations with risk of
exposure to hazardous drugs
Rationale: A Class II BSC is used for compounding sterile
preparations that involve hazardous drugs, as it provides both
containment and sterility assurance.
5. Which of the following factors is critical in ensuring the
sterility of compounded intravenous (IV) solutions?
A. The sterility of the IV bag only
B. The sterility of the compounding equipment and ingredients
C. The time spent mixing the solution
D. The color of the IV solution
Answer: B) The sterility of the compounding equipment and
ingredients
Rationale: The sterility of the IV solution depends on the
cleanliness of both the compounding equipment and the
ingredients, which must be maintained during preparation to
prevent contamination.
6. According to USP <797>, how often should the surface of a
laminar airflow workbench (LAFW) be cleaned during
compounding?
sterility during sterile compounding?
A. Avoiding direct contact between the drug and the air
B. Wearing non-sterile gloves during preparation
C. Using alcohol-free solutions for disinfecting surfaces
D. Keeping all equipment in open trays
Answer: A) Avoiding direct contact between the drug and the air
Rationale: To maintain sterility, it is critical to avoid exposing the
drug to air, which can introduce microorganisms and particles,
compromising the preparation's sterility.
2. How should a pharmacist address a situation where a
compounded sterile preparation (CSP) has an incorrect label or is
missing necessary information?
A. Ignore the issue and dispense the preparation
B. Discard the preparation and prepare a new one with correct
labeling
C. Ask the patient to fill out the missing information
D. Submit the preparation to testing
Answer: B) Discard the preparation and prepare a new one with
correct labeling
,Rationale: Proper labeling is essential for patient safety, and any
CSP with incorrect or missing labeling should be discarded and
re-prepared with the correct information.
3. What is the purpose of performing an initial certification of the
compounding area?
A. To verify that equipment is working properly
B. To assess air quality, temperature, and other environmental
factors
C. To ensure that compounding personnel are following proper
hand hygiene protocols
D. To check that all supplies are in stock
Answer: B) To assess air quality, temperature, and other
environmental factors
Rationale: Initial certification is performed to ensure that the
compounding area meets all required environmental standards,
such as air quality and temperature control, before compounding
begins.
4. When should a compounding pharmacy use a Class II Biological
Safety Cabinet (BSC)?
A. For preparing non-sterile preparations
B. For preparing sterile preparations with risk of exposure to
hazardous drugs
, C. Only for testing new products
D. For packaging non-sterile compounds
Answer: B) For preparing sterile preparations with risk of
exposure to hazardous drugs
Rationale: A Class II BSC is used for compounding sterile
preparations that involve hazardous drugs, as it provides both
containment and sterility assurance.
5. Which of the following factors is critical in ensuring the
sterility of compounded intravenous (IV) solutions?
A. The sterility of the IV bag only
B. The sterility of the compounding equipment and ingredients
C. The time spent mixing the solution
D. The color of the IV solution
Answer: B) The sterility of the compounding equipment and
ingredients
Rationale: The sterility of the IV solution depends on the
cleanliness of both the compounding equipment and the
ingredients, which must be maintained during preparation to
prevent contamination.
6. According to USP <797>, how often should the surface of a
laminar airflow workbench (LAFW) be cleaned during
compounding?
