EXAM 2 NSG124: 2025/2026, WITH CORRECT/ACCURATE ANSWERS

EXAM 2 NSG124: 2025/2026, WITH
CORRECT/ACCURATE ANSWERS
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Selective Toxicity - CORRECT ANSWERS- Ability of a drug to injure
a target cell or target organism w/o injuring other cells or
organisms that are in intimate contact with the target



Penicillins - Classification - CORRECT ANSWERS- classified by 4
major groups;

1. Narrow Spectrum - that are penicillin sensitive

2. Narrow Spectrum - that are penicillin resistant

3. Broad spectrum penicillins (aminopenicillins)

4. Extended - spectrum penicillins (Antipseudomonal penicillins)



Penicillins - Action, Use & Resistance - CORRECT ANSWERS-
Penicillins weakens cell wall, causing bacteria to take up
excessive amounts of water and rupture



as a result, Penicillins are generally bactericidal



***important; Penicillins are active only against bacteria that are
undergoing growth and division***

, Penicillins - Weaken Wall by... - CORRECT ANSWERS- 2 actions;



1. inhibition of trasnpeptidases

2. disinhibition (Activation) of autolysins



Broad Spectrum Penicillins (aminopenicillins) - CORRECT
ANSWERS- Drugs;

-Ampicillin

-Amoxicillin



Extended Spectrum Penicillins (Antipseudomonal Penicillins ) -
CORRECT ANSWERS- Drug:

- Piperacillin



Side effects and Toxicities - Penicillins - CORRECT ANSWERS-
Severe: Inadvertent intra-arterial injection can produce severe
reactions (Gangrene, necrosis, sloughing of tissue)



Mild: If allergy to Penicillins, use of cephalosporin is likely safe



Drug to drug Interaction: Amino glycosides



Penicillins - Action, effect, toxicity, allergy and interactions -
CORRECT ANSWERS- Penicillin G - least toxic of ALL antibiotics
and among the safest of all meds