EXAM 2 NSG124: 2025/2026, WITH
CORRECT/ACCURATE ANSWERS
Selective Toxicity - CORRECT ANSWERS- Ability of a drug to injure
a target cell or target organism w/o injuring other cells or
organisms that are in intimate contact with the target
Penicillins - Classification - CORRECT ANSWERS- classified by 4
major groups;
1. Narrow Spectrum - that are penicillin sensitive
2. Narrow Spectrum - that are penicillin resistant
3. Broad spectrum penicillins (aminopenicillins)
4. Extended - spectrum penicillins (Antipseudomonal penicillins)
Penicillins - Action, Use & Resistance - CORRECT ANSWERS-
Penicillins weakens cell wall, causing bacteria to take up
excessive amounts of water and rupture
as a result, Penicillins are generally bactericidal
***important; Penicillins are active only against bacteria that are
undergoing growth and division***
, Penicillins - Weaken Wall by... - CORRECT ANSWERS- 2 actions;
1. inhibition of trasnpeptidases
2. disinhibition (Activation) of autolysins
Broad Spectrum Penicillins (aminopenicillins) - CORRECT
ANSWERS- Drugs;
-Ampicillin
-Amoxicillin
Extended Spectrum Penicillins (Antipseudomonal Penicillins ) -
CORRECT ANSWERS- Drug:
- Piperacillin
Side effects and Toxicities - Penicillins - CORRECT ANSWERS-
Severe: Inadvertent intra-arterial injection can produce severe
reactions (Gangrene, necrosis, sloughing of tissue)
Mild: If allergy to Penicillins, use of cephalosporin is likely safe
Drug to drug Interaction: Amino glycosides
Penicillins - Action, effect, toxicity, allergy and interactions -
CORRECT ANSWERS- Penicillin G - least toxic of ALL antibiotics
and among the safest of all meds
CORRECT/ACCURATE ANSWERS
Selective Toxicity - CORRECT ANSWERS- Ability of a drug to injure
a target cell or target organism w/o injuring other cells or
organisms that are in intimate contact with the target
Penicillins - Classification - CORRECT ANSWERS- classified by 4
major groups;
1. Narrow Spectrum - that are penicillin sensitive
2. Narrow Spectrum - that are penicillin resistant
3. Broad spectrum penicillins (aminopenicillins)
4. Extended - spectrum penicillins (Antipseudomonal penicillins)
Penicillins - Action, Use & Resistance - CORRECT ANSWERS-
Penicillins weakens cell wall, causing bacteria to take up
excessive amounts of water and rupture
as a result, Penicillins are generally bactericidal
***important; Penicillins are active only against bacteria that are
undergoing growth and division***
, Penicillins - Weaken Wall by... - CORRECT ANSWERS- 2 actions;
1. inhibition of trasnpeptidases
2. disinhibition (Activation) of autolysins
Broad Spectrum Penicillins (aminopenicillins) - CORRECT
ANSWERS- Drugs;
-Ampicillin
-Amoxicillin
Extended Spectrum Penicillins (Antipseudomonal Penicillins ) -
CORRECT ANSWERS- Drug:
- Piperacillin
Side effects and Toxicities - Penicillins - CORRECT ANSWERS-
Severe: Inadvertent intra-arterial injection can produce severe
reactions (Gangrene, necrosis, sloughing of tissue)
Mild: If allergy to Penicillins, use of cephalosporin is likely safe
Drug to drug Interaction: Amino glycosides
Penicillins - Action, effect, toxicity, allergy and interactions -
CORRECT ANSWERS- Penicillin G - least toxic of ALL antibiotics
and among the safest of all meds
