GENERAL PATHOLOGY - FINAL EXAM
QUESTIONS WITH CORRECT ANSWERS
A 53 year old man suffers a cardiac arrest and his wife calls emergency services. The
paramedics arrive a few minutes later and begin life support measures. A regular heart
rate is established after 40 minutes of resuscitative efforts as he is being transported to
the hospital. A thrombolytic agent (tPA) is administered. Which of the following cellular
processes is most likely to occur in his myocardium immediately following administration
of the tPA? - Answer-Free radical injury
All are nuclear changes in irreversible cell injury except? - Answer-Autolysis
Hyperplasia is an increase in the size of the cells and eventually an increase in the size
of the organ. - Answer-False
Identify the cytoskeletal structure composed of actin - Answer-Microfilaments
The difference between wet and dry gangrene. - Answer-Presence of infection
The cellular response to injury depends on the following except - Answer-Cellular
adaptability
A 30 year old man goes skiing, sustains a left femoral fracture. His leg is placed in a
plaster cast. After the leg has been immobilized for several weeks the diameter of the
left calf has decreased. This would be? - Answer-Atrophy
Pathology studies all of the following except? - Answer-Clinical management
Caseous necrosis has what kind of appearance? - Answer-Gross cheesy appearance
ATP depletion results in the decline in mitochondrial permeability which - Answer-
Associated with leakage of cytochrome c from the inner membrane
Which of the following processes is most likely occurring in the endometrium just before
the onset of bleeding? - Answer-Apoptosis
Which of the following processes that occurred in the breast during pregnancy allowed
her to breastfeed the infant? - Answer-Lobular hypoplasia
A 22 year old woman has congenital anemia, that has required multiple blood
transfusions of RBC for many years. Which of the following findings would most likely
appear in a liver biopsy specimen. - Answer-Hemosiderosis and hepatocytes
, Caspases are enzymes that are activated during initiating phase of apoptosis - Answer-
False
An autopsy the heart of a 63 year old man weighs only 250 grams and has small right
and left ventricles. The myocardium is firm with a brown yellow color throughout. Which
of these substances would most likely be found in the myocardial fibers of the heart. -
Answer-Lipofuscin
A tissue preparation is experimentally subjected to a hypoxia environment. The cells in
this tissue begin to swell and chromatin begins to clump in the nucleus. Which of the
following ions released from mitochondria leads to these findings and eventual cell
death. - Answer-Calcium
A man fully expects to live long because that he has read that caloric restrictions
prolong life. In this man which of the following proteins will most likely mediate the effect
of caloric restriction and increase longevity. - Answer-Sirtuin
Types of adaptation include all of the following except - Answer-Dysplasia
A military personnel twisted his ankle and went to the clinic to take care of the injury.
The X-ray of the foot showed multiple increased densities in the tendons of the foot.
This finding can be explained as? - Answer-Dystrophic calcification
Hypoxic injury is a decrease in oxygen supply but the blood flow continues. - Answer-
True
An autopsy of an alcoholic person was performed. Which are the probable pathologic
findings found in the persons liver. - Answer-Steatosis
Atherosclerotic plaque formation includes all of the following steps except - Answer-
Antigen antibody Complex deposition
Metastatic calcification causes include all of the following except - Answer-Decreased
PTH
Dry gangrene is associated with? - Answer-Coagulative necrosis
A 2 year old presents with recurrent chest infections, which of the following most closely
characterizes the abnormality in the individual? - Answer-Periciliary function
Psammoma bodies are structures found in the tissue of patients with papillary thyroid
carcinoma. - Answer-True
Necrosis includes all of the following except: - Answer-Hyaline necrosis
A consequence of mitochondrial damage is? - Answer-Leakage of cytochrome c
QUESTIONS WITH CORRECT ANSWERS
A 53 year old man suffers a cardiac arrest and his wife calls emergency services. The
paramedics arrive a few minutes later and begin life support measures. A regular heart
rate is established after 40 minutes of resuscitative efforts as he is being transported to
the hospital. A thrombolytic agent (tPA) is administered. Which of the following cellular
processes is most likely to occur in his myocardium immediately following administration
of the tPA? - Answer-Free radical injury
All are nuclear changes in irreversible cell injury except? - Answer-Autolysis
Hyperplasia is an increase in the size of the cells and eventually an increase in the size
of the organ. - Answer-False
Identify the cytoskeletal structure composed of actin - Answer-Microfilaments
The difference between wet and dry gangrene. - Answer-Presence of infection
The cellular response to injury depends on the following except - Answer-Cellular
adaptability
A 30 year old man goes skiing, sustains a left femoral fracture. His leg is placed in a
plaster cast. After the leg has been immobilized for several weeks the diameter of the
left calf has decreased. This would be? - Answer-Atrophy
Pathology studies all of the following except? - Answer-Clinical management
Caseous necrosis has what kind of appearance? - Answer-Gross cheesy appearance
ATP depletion results in the decline in mitochondrial permeability which - Answer-
Associated with leakage of cytochrome c from the inner membrane
Which of the following processes is most likely occurring in the endometrium just before
the onset of bleeding? - Answer-Apoptosis
Which of the following processes that occurred in the breast during pregnancy allowed
her to breastfeed the infant? - Answer-Lobular hypoplasia
A 22 year old woman has congenital anemia, that has required multiple blood
transfusions of RBC for many years. Which of the following findings would most likely
appear in a liver biopsy specimen. - Answer-Hemosiderosis and hepatocytes
, Caspases are enzymes that are activated during initiating phase of apoptosis - Answer-
False
An autopsy the heart of a 63 year old man weighs only 250 grams and has small right
and left ventricles. The myocardium is firm with a brown yellow color throughout. Which
of these substances would most likely be found in the myocardial fibers of the heart. -
Answer-Lipofuscin
A tissue preparation is experimentally subjected to a hypoxia environment. The cells in
this tissue begin to swell and chromatin begins to clump in the nucleus. Which of the
following ions released from mitochondria leads to these findings and eventual cell
death. - Answer-Calcium
A man fully expects to live long because that he has read that caloric restrictions
prolong life. In this man which of the following proteins will most likely mediate the effect
of caloric restriction and increase longevity. - Answer-Sirtuin
Types of adaptation include all of the following except - Answer-Dysplasia
A military personnel twisted his ankle and went to the clinic to take care of the injury.
The X-ray of the foot showed multiple increased densities in the tendons of the foot.
This finding can be explained as? - Answer-Dystrophic calcification
Hypoxic injury is a decrease in oxygen supply but the blood flow continues. - Answer-
True
An autopsy of an alcoholic person was performed. Which are the probable pathologic
findings found in the persons liver. - Answer-Steatosis
Atherosclerotic plaque formation includes all of the following steps except - Answer-
Antigen antibody Complex deposition
Metastatic calcification causes include all of the following except - Answer-Decreased
PTH
Dry gangrene is associated with? - Answer-Coagulative necrosis
A 2 year old presents with recurrent chest infections, which of the following most closely
characterizes the abnormality in the individual? - Answer-Periciliary function
Psammoma bodies are structures found in the tissue of patients with papillary thyroid
carcinoma. - Answer-True
Necrosis includes all of the following except: - Answer-Hyaline necrosis
A consequence of mitochondrial damage is? - Answer-Leakage of cytochrome c
