SYSTEMS PATHOLOGY EXAM REVIEW
QUESTIONS WITH COMPLETE
SOLUTIONS
A disorder of coagulation that is caused by a loss of collagen in the skin and hence the
production of increased blood vessel fragility? - Answer-Senile Purpura?
Malignant hypertension causes which change in the microvasculature of the kidney? -
Answer-Hyperplastic arteriosclerosis
Which of the following are factors that are involved in the etiology of acute bacterial
endocarditis? - Answer-Staphylococcus aureus bacteremia
Aschoff bodies are seen histologically in which one of the following diseases? - Answer-
Acute Rheumatic Fever
Which is the Most common congenital cardiac anomaly? - Answer-Ventricular Septal
Defect
If the myocardium ruptures following a myocardial infection, what abnormal process
occurred to cause the rupture? - Answer-Liquefactive Necrosis?
The disease of coagulation that is inherited in a sex-linked recessive manner and
causes a deficiency of Factor 9? - Answer-Hemophilia B
The MOST common cause of acute cor pulmonale is? - Answer-Pulmonary Embolism
(acute)
A 45 year old woman who works as a bank teller notices at the end of her 8 hour shift
that her lower legs and feet are swollen, although there was no swelling at the
beginning of the day. There is no pain or erythema associated with this swelling. The
woman is otherwise healthy and takes no medications; laboratory testing reveals normal
liver and renal function. Which of the following mechanisms best explains this
phenomenon? - Answer-Increase hydrostatic pressure
Which one of the following conditions is associated with Kawasaki's syndrome? -
Answer-Coronary Artery aneurysm
A harsh, waxing and waning, machinery-like murmur is auscultated in the upper chest of
a 2 year old child with a history of infective endocarditis. Angiography reveals mild
pulmonary hypertension. Echocardiography shows all valves to be normal in
configuration. Which of the following lesions did the angiogram most likely show? -
Answer-Patent Ductus Arteriosus (PDA)
, The finding of a nutmeg patter to the cut surface of the liver suggests which one of the
following conditions? - Answer-Chronic Right Heart Failure
50% of myocardial infarctions are due to disease of which blood vessels? - Answer-Left
Anterior Interventricular
The type of leukemia that has been most often associated with specific abnormal
chromosome known as the Philadelphia Chromosome? - Answer-Chronic Myelocytic
(myeloid) Leukemia
A probably autoimmune condition of platelets that is seen in young children following a
viral infection and that causes hemorrhage due to destruction of platelets by the spleen?
- Answer-Acute Idiopathic Thrombocytopenic Purpura
Kaposi's sarcoma, a vascular neoplasm, is MOST likely to be found in association with
which one of the following diseases? - Answer-Acquired immunodeficiency syndrome
Wernicke's Korsakoff syndrome, which usually includes amnesia, confabulation, and
general mental deterioration, is typically caused by a deficiency of? - Answer-Vitamin
B1
The human neoplasm demonstrating extremely mitotic rate, "starry sky" microscopic
patter and jaw bone or abdominal region location is? - Answer-Burkitt Lymphoma
A dissecting aneurysm of the aorta arises in association with which of the following
diseases? - Answer-Marfan's Syndrome
A disorder of coagulation that is caused by a loss of collagen in the skin and hence the
production of increase blood vessel fragility? - Answer-Senile Purpura
Primary hemodynamic features of heart failure include decreased cardiac output and? -
Answer-Elevated systemic and pulmonary venous pressure
In chronic rheumatic heart disease the valve MOST frequently affected are? - Answer-
Mitral
A patient with acute MI suddenly develops acute mitral insufficiency on the seventh day
after the infarction. The BEST explanation for this is? - Answer-Papillary Muscle
Rupture
Which one of the following disease is associated with Marfan's Syndrome? - Answer-
Cystic Medial Necrosis
At autopsy, the thoracic aorta of a 73 year old male has a dilated root and arch, giving
the intimal surface a "tree bark" appearance. Microscopically, the aorta shows an
QUESTIONS WITH COMPLETE
SOLUTIONS
A disorder of coagulation that is caused by a loss of collagen in the skin and hence the
production of increased blood vessel fragility? - Answer-Senile Purpura?
Malignant hypertension causes which change in the microvasculature of the kidney? -
Answer-Hyperplastic arteriosclerosis
Which of the following are factors that are involved in the etiology of acute bacterial
endocarditis? - Answer-Staphylococcus aureus bacteremia
Aschoff bodies are seen histologically in which one of the following diseases? - Answer-
Acute Rheumatic Fever
Which is the Most common congenital cardiac anomaly? - Answer-Ventricular Septal
Defect
If the myocardium ruptures following a myocardial infection, what abnormal process
occurred to cause the rupture? - Answer-Liquefactive Necrosis?
The disease of coagulation that is inherited in a sex-linked recessive manner and
causes a deficiency of Factor 9? - Answer-Hemophilia B
The MOST common cause of acute cor pulmonale is? - Answer-Pulmonary Embolism
(acute)
A 45 year old woman who works as a bank teller notices at the end of her 8 hour shift
that her lower legs and feet are swollen, although there was no swelling at the
beginning of the day. There is no pain or erythema associated with this swelling. The
woman is otherwise healthy and takes no medications; laboratory testing reveals normal
liver and renal function. Which of the following mechanisms best explains this
phenomenon? - Answer-Increase hydrostatic pressure
Which one of the following conditions is associated with Kawasaki's syndrome? -
Answer-Coronary Artery aneurysm
A harsh, waxing and waning, machinery-like murmur is auscultated in the upper chest of
a 2 year old child with a history of infective endocarditis. Angiography reveals mild
pulmonary hypertension. Echocardiography shows all valves to be normal in
configuration. Which of the following lesions did the angiogram most likely show? -
Answer-Patent Ductus Arteriosus (PDA)
, The finding of a nutmeg patter to the cut surface of the liver suggests which one of the
following conditions? - Answer-Chronic Right Heart Failure
50% of myocardial infarctions are due to disease of which blood vessels? - Answer-Left
Anterior Interventricular
The type of leukemia that has been most often associated with specific abnormal
chromosome known as the Philadelphia Chromosome? - Answer-Chronic Myelocytic
(myeloid) Leukemia
A probably autoimmune condition of platelets that is seen in young children following a
viral infection and that causes hemorrhage due to destruction of platelets by the spleen?
- Answer-Acute Idiopathic Thrombocytopenic Purpura
Kaposi's sarcoma, a vascular neoplasm, is MOST likely to be found in association with
which one of the following diseases? - Answer-Acquired immunodeficiency syndrome
Wernicke's Korsakoff syndrome, which usually includes amnesia, confabulation, and
general mental deterioration, is typically caused by a deficiency of? - Answer-Vitamin
B1
The human neoplasm demonstrating extremely mitotic rate, "starry sky" microscopic
patter and jaw bone or abdominal region location is? - Answer-Burkitt Lymphoma
A dissecting aneurysm of the aorta arises in association with which of the following
diseases? - Answer-Marfan's Syndrome
A disorder of coagulation that is caused by a loss of collagen in the skin and hence the
production of increase blood vessel fragility? - Answer-Senile Purpura
Primary hemodynamic features of heart failure include decreased cardiac output and? -
Answer-Elevated systemic and pulmonary venous pressure
In chronic rheumatic heart disease the valve MOST frequently affected are? - Answer-
Mitral
A patient with acute MI suddenly develops acute mitral insufficiency on the seventh day
after the infarction. The BEST explanation for this is? - Answer-Papillary Muscle
Rupture
Which one of the following disease is associated with Marfan's Syndrome? - Answer-
Cystic Medial Necrosis
At autopsy, the thoracic aorta of a 73 year old male has a dilated root and arch, giving
the intimal surface a "tree bark" appearance. Microscopically, the aorta shows an
